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KCNK1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS153487

The potassium channel, subfamily K, member 1 (KCNK1), is member of the superfamily of potassium channel proteins containing two pore-forming P domains (1,2). KCNK1 is a ubiquitous human weakly inward rectifying K+ channel that is widely expressed in human… More details

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Product Overview

Online Datasheet in PDF
Product Name
KCNK1, Polyclonal Antibody
Full Product Name
KCNK1 Antibody
Product Gene Name
Product Synonym Names
Potassium channel subfamily K member 1; DPK; HOHO; K2P1; K2p1.1; KCNO1; TWIK-1; TWIK1; potassium channel, subfamily K, member 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
KCNK1 antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
KCNK1 antibody is human, mouse and rat reactive. KCNK1 antibody is predicted to not cross-react with other KCNK proteins.
Preparation and Storage
KCNK1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
Antibody/Peptide Pairs
KCNK1 peptide (MBS153950) is used for blocking the activity of KCNK1 antibody (MBS153487)
Molecular Weight
Predicted: 37 kDa

Observed: 35 kDa
OMIM
601745
3D Structure
ModBase 3D Structure for O00180
Conjugate
Unconjugated
Immunogen
KCNK1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human KCNK1.
Buffer
KCNK1 antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-KCNK1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-KCNK1 antibody
KCNK1 antibody can be used for detection of KCNK1 by Western blot at 1 - 2 mug/ml. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-KCNK1 antibody

Western blot analysis of KCNK1 in 3T3 cell lysate with KCNK1 antibody at 1 μg/ml.
Rabbit Anti-KCNK1 Polyclonal Antibody – Cat# MBS153487

Immunohistochemistry (IHC) of anti-KCNK1 antibody

Immunohistochemistry of KCNK1 in mouse brain tissue with KCNK1 antibody at 5 μg/ml.
Rabbit Anti-KCNK1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS153487

Immunofluorescence (IF) of anti-KCNK1 antibody

Immunofluorescence of KCNK1 in mouse brain tissue with KCNK1 antibody at 20 μg/ml.
Rabbit Anti-KCNK1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS153487

Other Notes

Small volumes of anti-KCNK1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KCNK1 purchase

MBS153487 is an antibody targeting KCNK1. Also known as KCNK1 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KCNK1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
potassium channel subfamily K member 1
NCBI Official Synonym Full Names
potassium channel, two pore domain subfamily K, member 1
NCBI Official Symbol
KCNK1
NCBI Official Synonym Symbols
DPK; HOHO; K2P1; KCNO1; TWIK1; K2p1.1; TWIK-1
UniProt Protein Name
Potassium channel subfamily K member 1
UniProt Synonym Protein Names
Inward rectifying potassium channel protein TWIK-1; Potassium channel KCNO1
UniProt Gene Name
KCNK1
UniProt Synonym Gene Names
HOHO1; KCNO1; TWIK1
UniProt Entry Name
KCNK1_HUMAN
NCBI Protein Information
potassium channel subfamily K member 1; potassium channel KCNO1; inward rectifying potassium channel protein TWIK-1; potassium inwardly-rectifying channel, subfamily K, member 1; tandem of P domains in a weak inward rectifying K+ channel 1

NCBI Summary for KCNK1

This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008]

UniProt Comments for KCNK1

KCNK1: Weakly inward rectifying potassium channel. Homodimer (Potential). Widely expressed with high levels in heart and brain and lower levels in placenta, lung, liver and kidney. Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q42-q43

Cellular Component: voltage-gated potassium channel complex; brush border membrane; apical plasma membrane; plasma membrane; endosome

Molecular Function: inward rectifier potassium channel activity

Biological Process: response to nicotine; synaptic transmission; potassium ion transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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