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NEUROG2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS153532

NGN2 Antibody: Neurogenin-2 (NGN2) is a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells and is expressed in neural progenitor cells within the developing central and peripheral nervous… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
NGN2 (NEUROG2), Polyclonal Antibody
Full Product Name
NGN2 Antibody
Product Gene Name
Product Synonym Names
NGN2; NGN2; Atoh4; ngn-2; Math4A; bHLHa8; ATOH4; BHLHA8; NGN2; Neurogenin-2; Class A basic helix-loop-helix protein 8; NGN-2; neurogenin 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
NGN2 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
NGN2 antibody is predicted to not cross-react with neurogenin 1.
Preparation and Storage
NGN2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
NGN2 peptide (MBS154076) is used for blocking the activity of NGN2 antibody (MBS153532)
Molecular Weight
30 kDa
OMIM
606624
3D Structure
ModBase 3D Structure for Q9H2A3
Conjugate
Unconjugated
Immunogen
Rabbit polyclonal NGN2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human NGN2.
Buffer
NGN2 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-NEUROG2 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-NEUROG2 antibody
NGN2 antibody can be used for detection of NGN2 by Western blot at 1 - 2 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-NEUROG2 antibody

Western blot analysis of NGN2 in mouse small intestine tissue lysate with NGN2 antibody at (A) 1 and (B) 2 μg/mL.
Rabbit Anti-NEUROG2 Polyclonal Antibody – Cat# MBS153532

Immunofluorescence (IF) of anti-NEUROG2 antibody

Immunofluorescence of NGN2 in human brain tissue with NGN2 antibody at 20 μg/mL.
Rabbit Anti-NEUROG2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS153532

Other Notes

Small volumes of anti-NEUROG2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NEUROG2 purchase

MBS153532 is an antibody targeting NEUROG2. Also known as NGN2 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NEUROG2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
neurogenin-2
NCBI Official Synonym Full Names
neurogenin 2
NCBI Official Symbol
NEUROG2
NCBI Official Synonym Symbols
NGN2; Atoh4; ngn-2; Math4A; bHLHa8
UniProt Protein Name
Neurogenin-2
UniProt Synonym Protein Names
Class A basic helix-loop-helix protein 8; bHLHa8; Protein atonal homolog 4
Protein Family
UniProt Gene Name
NEUROG2
UniProt Synonym Gene Names
ATOH4; BHLHA8; NGN2; NGN-2; bHLHa8
UniProt Entry Name
NGN2_HUMAN
NCBI Protein Information
neurogenin-2; protein atonal homolog 4; class A basic helix-loop-helix protein 8

NCBI Summary for NEUROG2

This gene encodes a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells and is expressed in neural progenitor cells within the developing central and peripheral nervous systems. The protein product of this gene also plays a role in the differentiation and survival of midbrain dopaminergic neurons. [provided by RefSeq, Apr 2012]
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UniProt Comments for NEUROG2

neurogenin 2: Transcriptional regulator. Involved in neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3').

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 4q25

Cellular Component: nucleus

Molecular Function: protein dimerization activity; sequence-specific DNA binding

Biological Process: axon guidance; cell fate commitment; transcription, DNA-dependent; forebrain development; cell maturation; neuron migration; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; positive regulation of neuron differentiation; central nervous system neuron development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-NEUROG2 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >110 publications with NEUROG2 and Brain
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