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DDX41 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS153565

DDX41 Antibody: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure such as translation initiation, nuclear and… More details

$530 / 0.1 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
DDX41, Polyclonal Antibody
Full Product Name
DDX41 Antibody
Product Gene Name
Product Synonym Names
DDX41; ABS; ABS; Probable ATP-dependent RNA helicase DDX41; DEAD box protein 41; DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
DDX41 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
At least two isoforms of DDX41 are known to exist; this antibody will detect both isoforms.
Preparation and Storage
DDX41 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
Antibody/Peptide Pairs
DDX41 peptide (MBS154153) is used for blocking the activity of DDX41 antibody (MBS153565)
Molecular Weight
Predicted: 68 kDa

Observed: 70 kDa
OMIM
608170
3D Structure
ModBase 3D Structure for Q9UJV9
Conjugate
Unconjugated
Immunogen
DDX41 antibody was raised against a 17 amino acid peptide near the amino terminus of human DDX41.
Buffer
DDX41 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-DDX41 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-DDX41 antibody
DDX41 antibody can be used for detection of DDX41 by Western blot at 1 - 2 mug/mL.

Western Blot (WB) of anti-DDX41 antibody

Western blot analysis of DDX41 in rat brain tissue lysate with DDX41 antibody at 1 μg/mL.
Rabbit Anti-DDX41 Polyclonal Antibody – Cat# MBS153565

Immunohistochemistry (IHC) of anti-DDX41 antibody

Immunohistochemistry of DDX41 in rat brain tissue with DDX41 antibody at 2.5 μg/ml.
Rabbit Anti-DDX41 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS153565

Immunofluorescence (IF) of anti-DDX41 antibody

Immunofluorescence of DDX41 in rat brain tissue with DDX41 antibody at 20 μg/ml.
Rabbit Anti-DDX41 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS153565

Other Notes

Small volumes of anti-DDX41 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DDX41 purchase

MBS153565 is an antibody targeting DDX41. Also known as DDX41 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DDX41. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
probable ATP-dependent RNA helicase DDX41
NCBI Official Synonym Full Names
DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
NCBI Official Symbol
DDX41
NCBI Official Synonym Symbols
ABS
UniProt Protein Name
Probable ATP-dependent RNA helicase DDX41
UniProt Synonym Protein Names
DEAD box protein 41; DEAD box protein abstrakt homolog
UniProt Gene Name
DDX41
UniProt Synonym Gene Names
ABS
UniProt Entry Name
DDX41_HUMAN
NCBI Protein Information
probable ATP-dependent RNA helicase DDX41; 2900024F02Rik; DEAD box protein 41; putative RNA helicase; DEAD-box protein abstrakt; DEAD box protein abstrakt homolog

NCBI Summary for DDX41

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Based on studies in Drosophila, the abstrakt gene is widely required during post-transcriptional gene expression. [provided by RefSeq, Jul 2008]
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UniProt Comments for DDX41

DDX41: Probable ATP-dependent RNA helicase. Is required during post-transcriptional gene expression. May be involved in pre-mRNA splicing. Belongs to the DEAD box helicase family. DDX41 subfamily.

Protein type: RNA splicing; Helicase; Spliceosome; RNA-binding; EC 3.6.4.13

Chromosomal Location of Human Ortholog: 5q35.3

Cellular Component: membrane; endoplasmic reticulum; cytosol

Molecular Function: protein binding; DNA binding; zinc ion binding; helicase activity; ATP binding

Biological Process: RNA processing; nuclear mRNA splicing, via spliceosome; regulation of interferon type I production; apoptosis; multicellular organismal development; positive regulation of interferon type I production; innate immune response; positive regulation of transcription from RNA polymerase II promoter; defense response to virus
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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