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TENM1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS153612

The teneurin transmembrane protein 1 (TENM1) is a member of a family of four neuronal cell surface proteins homologous to the Drosophila pair-rule gene Ten-m (1,2). TENM1 is expressed primarily in the developing central nervous system and may be… More details

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Product Overview

Online Datasheet in PDF
Product Name
TENM1, Polyclonal Antibody
Full Product Name
TENM1 Antibody
Product Gene Name
anti-TENM1 antibody
Product Synonym Names
Teneurin transmembrane protein 1; teneurin-1; ODZ1; ODZ3; TEN-M1; TNM; TNM1; teneurin transmembrane protein 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
TENM1 antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
TENM1 antibody is human, mouse and rat reactive. TENM1 antibody is predicted to not cross-react with other members of the TENM family.
Preparation and Storage
TENM1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
Antibody/Peptide Pairs
TENM1 peptide (MBS154119) is used for blocking the activity of TENM1 antibody (MBS153612)
Molecular Weight
Predicted: 301 kDa

Observed: 280 kDa
OMIM
300588
3D Structure
ModBase 3D Structure for Q9UKZ4
Conjugate
Unconjugated
Immunogen
TENM1 antibody was raised against an 18 amino acid peptide near the amino terminus of human TENM1.
Buffer
TENM1 antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-TENM1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-TENM1 antibody
TENM1 antibody can be used for detection of TENM1 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.

Western Blot (WB) of anti-TENM1 antibody

Western blot analysis of TENM1 in human brain tissue lysate with TENM1 antibody at 1 μg/ml.
Rabbit Anti-TENM1 Polyclonal Antibody – Cat# MBS153612

Immunohistochemistry (IHC) of anti-TENM1 antibody

Immunohistochemistry of TENM1 in mouse brain tissue with TENM1 antibody at 5 μg/mL.
Rabbit Anti-TENM1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS153612

Immunofluorescence (IF) of anti-TENM1 antibody

Immunofluorescence of TENM1 in mouse brain tissue with TENM1 antibody at 20 μg/mL.
Rabbit Anti-TENM1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS153612

Other Notes

Small volumes of anti-TENM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TENM1 purchase

MBS153612 is an antibody targeting TENM1. Also known as TENM1 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TENM1. It may not necessarily be applicable to this product.

NCBI GI #
253970444
NCBI GeneID
10178
NCBI Accession #
NP_001156750
UniProt Primary Accession #
Q9UKZ4
UniProt Secondary Accession #
Q5JZ17; B2RTR5
UniProt Related Accession #
Q9UKZ4
GenBank Nucleotide #
NM_001163278.1
NCBI Official Full Name
teneurin-1 isoform 1
NCBI Official Synonym Full Names
teneurin transmembrane protein 1
NCBI Official Symbol
TENM1
NCBI Official Synonym Symbols
TNM; ODZ1; ODZ3; TNM1; TEN-M1
UniProt Protein Name
Teneurin-1
UniProt Synonym Protein Names
Protein Odd Oz/ten-m homolog 1; Tenascin-M1; Ten-m1; Teneurin transmembrane protein 1Cleaved into the following 2 chains:Ten-1 intracellular domain; IDten-1; Ten-1 ICD; Teneurin C-terminal-associated peptide; TCPA-1Alternative name(s):Ten-1 extracellular domain; Ten-1 ECD
UniProt Gene Name
TENM1
UniProt Synonym Gene Names
ODZ1; TNM1; Ten-1; Ten-m1; IDten-1; Ten-1 ICD; TCPA-1; Ten-1 ECD
UniProt Entry Name
TEN1_HUMAN
NCBI Protein Information
teneurin-1; ten-1; teneurin 1; tenascin M1; tenascin-M1; odz, odd Oz/ten-m homolog 1; protein Odd Oz/ten-m homolog 1; odz, odd Oz/ten-m homolog 1(Drosophila); odz (odd Oz/ten-m, Drosophila) homolog 3

NCBI Summary for TENM1

The protein encoded by this gene belongs to the tenascin family and teneurin subfamily. It is expressed in the neurons and may function as a cellular signal transducer. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
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UniProt Comments for TENM1

ODZ1: May function as a cellular signal transducer. Belongs to the tenascin family. Teneurin subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq25

Cellular Component: Golgi apparatus; cytoskeleton; nuclear matrix; integral to plasma membrane; perinuclear region of cytoplasm; endoplasmic reticulum; cytoplasm; extracellular region; plasma membrane; nuclear speck; nucleus

Molecular Function: heparin binding; protein homodimerization activity; protein heterodimerization activity

Biological Process: positive regulation of filopodium formation; nervous system development; negative regulation of cell proliferation; positive regulation of MAP kinase activity; transcription, DNA-dependent; positive regulation of actin filament polymerization; regulation of transcription from RNA polymerase III promoter; neuropeptide signaling pathway; immune response; positive regulation of peptidyl-serine phosphorylation
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Research Articles on TENM1

1. Subsequent analysis showed that the deletion in both cousins was identical and involved the whole SH2D1A gene and a part of the adjacent ODZ1 gene.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-TENM1 antibody

 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >1 publications with TENM1 and Brain Diseases
 Nervous System Diseases Antibodies  >1 publications with TENM1 and Nervous System Diseases
 Neoplasm Metastasis Antibodies  >1 publications with TENM1 and Neoplasm Metastasis
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