• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

GDPD5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS153670

The glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) protein, also known as GDE2, is a seven transmembrane, widely expressed protein (1) that is necessary for spinal motor neuron differentiation and retinoid-induced neuronal outgrowth… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GDPD5, Polyclonal Antibody
Full Product Name
GDPD5 Antibody
Product Gene Name
anti-GDPD5 antibody
Product Synonym Names
GDPD5; GDE2; PP1665; GDE2; PP6037; PP9363; UNQ1850/PRO3580; Glycerophosphodiester phosphodiesterase domain-containing protein 5; Glycerophosphodiester phosphodiesterase 2; glycerophosphodiester phosphodiesterase domain containing 5
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
GDPD5 antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
GDPD5 antibody is human, mouse and rat reactive. At least three isoforms of GDPD5 are known to exist.
Preparation and Storage
GDPD5 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
Antibody/Peptide Pairs
GDPD5 peptide (MBS153883) is used for blocking the activity of GDPD5 antibody (MBS153670)
Molecular Weight
Predicted: 40; 67 kDa

Observed: 52 kDa
OMIM
609632
3D Structure
ModBase 3D Structure for Q8WTR4
Conjugate
Unconjugated
Immunogen
GDPD5 antibody was raised against an 18 amino acid peptide near the amino terminus of human GDPD5.
Buffer
GDPD5 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-GDPD5 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-GDPD5 antibody
GDPD5 antibody can be used for detection of GDPD5 by Western blot at 1 - 2 mug/ml. Antibody can also be used for Immunohistochemistry at 5 mug/mL. For Immunoflorescence start at 20 mug/mL.

Western Blot (WB) of anti-GDPD5 antibody

Western blot analysis of GDPD5 in mouse kidney tissue lysate with GDPD5 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
Rabbit Anti-GDPD5 Polyclonal Antibody – Cat# MBS153670

Immunohistochemistry (IHC) of anti-GDPD5 antibody

Immunohistochemistry of GDPD5 in human kidney tissue with GDPD5 antibody at 5 μg/mL.
Rabbit Anti-GDPD5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS153670

Immunofluorescence (IF) of anti-GDPD5 antibody

Immunofluorescence of GDPD5 in human kidney tissue with GDPD5 antibody at 20 μg/mL.
Rabbit Anti-GDPD5 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS153670

Other Notes

Small volumes of anti-GDPD5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GDPD5 purchase

MBS153670 is an antibody targeting GDPD5. Also known as GDPD5 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GDPD5. It may not necessarily be applicable to this product.

NCBI GI #
189571657
NCBI GeneID
81544
NCBI Accession #
NP_110419
UniProt Primary Accession #
Q8WTR4
UniProt Secondary Accession #
Q49AQ5; Q6UX76; Q7Z4S0; Q8N781; Q8NCB7; Q8TB77
UniProt Related Accession #
Q8WTR4
GenBank Nucleotide #
NM_030792.6
NCBI Official Full Name
glycerophosphodiester phosphodiesterase domain-containing protein 5
NCBI Official Synonym Full Names
glycerophosphodiester phosphodiesterase domain containing 5
NCBI Official Symbol
GDPD5
NCBI Official Synonym Symbols
GDE2; PP1665
UniProt Protein Name
Glycerophosphodiester phosphodiesterase domain-containing protein 5
UniProt Synonym Protein Names
Glycerophosphodiester phosphodiesterase 2
Protein Family
Glycerophosphodiester phosphodiesterase
UniProt Gene Name
GDPD5
UniProt Synonym Gene Names
GDE2
UniProt Entry Name
GDPD5_HUMAN
NCBI Protein Information
glycerophosphodiester phosphodiesterase domain-containing protein 5; glycerophosphodiester phosphodiesterase 2

NCBI Summary for GDPD5

Glycerophosphodiester phosphodiesterases (GDPDs; EC 3.1.4.46), such as GDPD5, are involved in glycerol metabolism (Lang et al., 2008 [PubMed 17578682]).[supplied by OMIM, Jan 2010]

UniProt Comments for GDPD5

GDPD5: Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine. Belongs to the glycerophosphoryl diester phosphodiesterase family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; EC 3.1.-.-; Membrane protein, integral; Phosphodiesterase

Chromosomal Location of Human Ortholog: 11q13.4-q13.5

Cellular Component: growth cone; perinuclear region of cytoplasm; integral to membrane; endomembrane system

Molecular Function: glycerophosphodiester phosphodiesterase activity

Biological Process: glycerol metabolic process; negative regulation of Notch signaling pathway; lipid metabolic process; spinal cord motor neuron differentiation; positive regulation of neuron differentiation; regulation of timing of cell differentiation; neurite development; cerebral cortex neuron differentiation
Show more

Research Articles on GDPD5

1. Identification of GDPD5 as a glycerophosphocholine phosphodiesterase that probably participates in the regulation of choline phospholipid metabolism in breast cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-GDPD5 antibody

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >1 publications with GDPD5 and Breast Neoplasms

Organs/Tissues associated with anti-GDPD5 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with GDPD5 and Blood
 Heart Antibodies  >2 publications with GDPD5 and Heart
 Lung Antibodies  >2 publications with GDPD5 and Lung
 Kidney Antibodies  >2 publications with GDPD5 and Kidney
 Prostate Antibodies  >1 publications with GDPD5 and Prostate
 Testis Antibodies  >1 publications with GDPD5 and Testis
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000