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TMEM107 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS153723

Transmembrane protein 107 (TMEM 107) is critical for cilia formation and embryonic patterning (1). It is a 139 amino acid transmembrane protein encoded by a gene that maps to human chromosome 17 which is associated with two key tumor suppressor genes p53 and… More details

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Product Overview

Online Datasheet in PDF
Product Name
TMEM107, Polyclonal Antibody
Full Product Name
TMEM107 Antibody
Product Gene Name
Product Synonym Names
TMEM107 Antibody : GRVS638; PRO1268; Transmembrane protein 107; transmembrane protein 107
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
TMEM107 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
TMEM107 antibody is human specific. At least two isoforms of TMEM107 are known to exist.
Preparation and Storage
TMEM107antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
Antibody/Peptide Pairs
TMEM107 peptide (MBS153786) is used for blocking the activity of TMEM107 antibody (MBS153723)
Molecular Weight
Predicted: 16 kDa

Observed: 19kDa
3D Structure
ModBase 3D Structure for Q6UX40
Conjugate
Unconjugated
Immunogen
TMEM107 antibody was raised against a 19 amino acid peptide near the amino terminus of human TMEM107.
Buffer
TMEM107 Antibody is supplied in PBS containing 0.02% sodium azide.
Applications Tested/Suitable for anti-TMEM107 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-TMEM107 antibody
TMEM107 antibody can be used for detection of TMEM107 by Western blot at 1 - 2 mug/ml.

Western Blot (WB) of anti-TMEM107 antibody

Western blot analysis of TMEM107 in THP-1 cell lysate with TMEM107 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
Rabbit Anti-TMEM107 Polyclonal Antibody – Cat# MBS153723

Immunohistochemistry (IHC) of anti-TMEM107 antibody

Immunohistochemistry of TMEM107 in human lymph node tissue with TMEM107 antibody at 5 μg/mL.
Rabbit Anti-TMEM107 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS153723

Immunofluorescence (IF) of anti-TMEM107 antibody

Immunofluorescence of TMEM107 in human lymph node tissue with TMEM107 antibody at 20 μg/mL.
Rabbit Anti-TMEM107 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS153723

Other Notes

Small volumes of anti-TMEM107 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TMEM107 purchase

MBS153723 is an antibody targeting TMEM107. Also known as TMEM107 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TMEM107. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
transmembrane protein 107 isoform 1
NCBI Official Synonym Full Names
transmembrane protein 107
NCBI Official Symbol
TMEM107
NCBI Official Synonym Symbols
GRVS638; PRO1268
UniProt Protein Name
Transmembrane protein 107
Protein Family
UniProt Gene Name
TMEM107
UniProt Entry Name
TM107_HUMAN
NCBI Protein Information
transmembrane protein 107

UniProt Comments for TMEM107

TMEM107: Plays a role in cilia formation and embryonic patterning. Requires for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with GLI2 and GLI3 to pattern ventral and intermediate neuronal cell types. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: integral to membrane

Biological Process: neural tube patterning; cilium biogenesis; embryonic digit morphogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-TMEM107 antibody

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