SDS-PAGE analysis of Avian Influenza (H5) Hemagglutinin subunit HA1 on Coomassie Blue-stained 4-20% gradient gel.

Hemagglutinin (HA) Recombinant Protein

Name: HA Recombinant Protein; Hemagglutinin; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS154165
Price: 420 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS154165

Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA (1). Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting… More details

$420 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Hemagglutinin (HA), Recombinant Protein

Full Product Name

Hemagglutinin Recombinant Protein

Product Gene Name

HA recombinant protein

Product Synonym Names

H5N1 Hemagglutinin HA1; H5N1 Hemagglutinin; H5N1 HA1; HA1; Hemagglutinin

Sequence

aa. 17-338

Host

E Coli

Form/Format

Liquid; 1X PBS containing 0.1% SDS and 0.02% NaN3

Purity/Purification

~95%

Preparation and Storage

Ships on dry ice. Store in working aliquots at -70°C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Molecular Weight

39kDa (calculated)

3D Structure

ModBase 3D Structure for Q692M2

Fusion Tag

Fusion Partner: His-tag and strepll-tag at N-Terminus

Sequence

aa. 17-338

Species

Influenza A virus (A/chicken/Jilin/9/2004(H5N1))

Applications Tested/Suitable for HA recombinant protein

ELISA (EIA), Western Blot (WB)

Other Notes

Small volumes of HA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HA purchase

MBS154165 is a recombinant protein targeting HA. Also known as Hemagglutinin Recombinant Protein. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for HA. It may not necessarily be applicable to this product.

NCBI GI #

50365729

NCBI GeneID

3654620

NCBI Accession #

AAT76166

UniProt Primary Accession #

Q692M2

UniProt Related Accession #

Q9Q0U6

NCBI Official Full Name

hemagglutinin

NCBI Official Symbol

UniProt Protein Name

Hemagglutinin

Protein Family

Hemagglutinin

UniProt Gene Name

UniProt Entry Name

Q692M2_9INFA

NCBI Protein Information

hemagglutinin; HA1; HA2

UniProt Comments for HA

Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.

Research Articles on HA

1. The growth of H5N1 avian influenza viruses is affected by changes of glycosylation sites in HA protein.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.