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C18ORF42 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS154356

Little is known of the function of the protein encoded by Chromosome 18 open reading frame 18 (C18orf42), but it is preferentially expressed in neuronal tissue (1). It is thought to bind to the cAMP-dependent protein kinase A (PKA) and regulation its… More details

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Product Overview

Online Datasheet in PDF
Product Name
C18orf42, Polyclonal Antibody
Full Product Name
C18orf42 Antibody
Product Gene Name
Product Synonym Names
Chromosome 18 open reading frame 42
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
C18orf42 antibody is human specific.
Preparation and Storage
Store at 4 degree C for three months and -20 degree C, stable for up to one year.
Antibody/Peptide Pairs
C18orf42 peptide (MBS154424) is used for blocking the activity of C18orf42 antibody (MBS154356)
Molecular Weight
Predicted: 8 kDa
Observed: 12 kDa
OMIM
616427
3D Structure
ModBase 3D Structure for P0CW23
Immunogen
C18orf42 antibody was raised against a 16 amino acid peptide from near the center of human C18orf42.
Buffer
Supplied in PBS containing 0.02% sodium azide.
Positive Control 1
HeLa Cell Lysate
Conjugate
Unconjugated

Product Categories/Family for anti-C18orf42 antibody

Applications Tested/Suitable for anti-C18orf42 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-C18orf42 antibody
C18orf42 antibody can be used for the detection of C18orf42 by Western blot at 1 - 2 mug/mL.

Western Blot (WB) of anti-C18orf42 antibody

Western blot analysis of C18orf42 in HeLa cell lysate with C18orf42 antibody at 1 μg/ml.
Rabbit Anti-C18ORF42 Polyclonal Antibody – Cat# MBS154356

Immunocytochemistry (IHC) of anti-C18orf42 antibody

Immunocytochemistry of C18orf42 in HeLa cells with C18orf42 antibody at 2 μg/mL.
Rabbit Anti-C18ORF42 Polyclonal Antibody, Immunocytochemistry (IHC) – Cat# MBS154356

Immunofluorescence (IF) of anti-C18orf42 antibody

Immunofluorescence of C18orf42 in HeLa cells with C18orf42 antibody at 2 μg/mL.

Red: C18orf42 Antibody (8471)
Blue: DAPI staining
Rabbit Anti-C18ORF42 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS154356

Product References and Citations for anti-C18orf42 antibody

Fukuda M and Aizawa Y. Hypothetical gene C18orf42 encodes a novel protein kinase A-binding protein. Genes Cells 2015; 20:267-80.

Other Notes

Small volumes of anti-C18orf42 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for C18orf42 purchase

MBS154356 is an antibody targeting C18orf42. Also known as C18orf42 Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for C18orf42. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
A-kinase anchor protein C18orf42
NCBI Official Synonym Full Names
A kinase (PRKA) anchor inhibitor 1
NCBI Official Symbol
AKAIN1
NCBI Official Synonym Symbols
C18orf42
UniProt Protein Name
A-kinase anchor protein C18orf42
UniProt Gene Name
C18orf42
UniProt Entry Name
CR042_HUMAN
NCBI Protein Information
A-kinase anchor protein C18orf42

UniProt Comments for C18orf42

AKAIN1: Protein kinase A (PKA)-binding protein. Binds to type II regulatory subunits of protein kinase A (PKA) and may block the A- kinase anchoring protein (AKAP)-mediated subcellular localization of PKA. Binds cAMP-dependent protein kinase (PKA). Interacts specifically with RII-regulatory subunits of PKA (PRKAR2A and PRKAR2B).

Chromosomal Location of Human Ortholog: 18p11.31

Molecular Function: protein kinase A binding

Biological Process: protein localization
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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