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CHADL Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS154377

The Chondroadherin-like (CHADL) protein, also known as SLRR4B, is homologous to the Chondroadherin protein and is expressed cartillaginous tissues (1). Like Chondroadherin, CHADL belongs to the small leucine-rich proteoglycan (SLRP) family and class IV… More details

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Product Overview

Online Datasheet in PDF
Product Name
CHADL, Polyclonal Antibody
Full Product Name
CHADL Antibody
Product Gene Name
Product Synonym Names
Chondoadherin-like protein, SLRR4B
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
Affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
CHADL antibody is human, mouse and rat reactive. CHADL antibody is predicted to not cross-react with Chondroadherin protein.
Preparation and Storage
Store at 4 degree C for three months and -20 degree C, stable for up to one year.
Antibody/Peptide Pairs
CHADL peptide (MBS154398) is used for blocking the activity of CHADL antibody (MBS154377)
Molecular Weight
Predicted: 84 kDa
Observed: 86 kDa
OMIM
616236
3D Structure
ModBase 3D Structure for Q6NUI6
Immunogen
CHADL antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human CHADL.
Buffer
Supplied in PBS containing 0.02% sodium azide.
Positive Control 1
Rat Skeletal Muscle Tissue Lysate
Conjugate
Unconjugated

Product Categories/Family for anti-CHADL antibody

Applications Tested/Suitable for anti-CHADL antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-CHADL antibody
CHADL antibody can be used for the detection of CHADL by Western blot at 1 - 2 mug/mL.

Western Blot (WB) of anti-CHADL antibody

Western blot analysis of CHADL in mouse kidney tissue lysate with CHADL antibody at (A) 1 and (B) 2 μg/ml.
Rabbit Anti-CHADL Polyclonal Antibody – Cat# MBS154377

Immunohistochemistry (IHC) of anti-CHADL antibody

Immunohistochemistry of CHADL in mouse skeletal muscle tissue with CHADL antibody at 5 μg/mL.
Rabbit Anti-CHADL Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS154377

Immunofluorescence (IF) of anti-CHADL antibody

Immunofluorescence of CHADL in mouse skeletal muscle tissue with CHADL antibody at 20 μg/mL.

Red: CHADL Antibody (8423)
Blue: DAPI staining
Rabbit Anti-CHADL Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS154377

Immunohistochemistry (IHC) of anti-CHADL antibody

Immunohistochemistry of CHADL in mouse skeletal muscle tissue with CHADL antibody at 5 μg/mL.
Rabbit Anti-CHADL Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS154377

Product References and Citations for anti-CHADL antibody

Tillgren V, Ho JC, Onnerfjord P, et al. The novel small leucine-rich protein chondroadherin-like (CHADL) is expressed in cartilage and modulates chondrocyte differentitation. J. Biol. Chem. 2015; 290:918-25. Neame PJ, Sommarin Y, Boynton RE, et al. The structure of a 38-kDa leucine-rich protein (chondroadherin) isolated from bovine cartilage. J. Biol. Chem. 1994; 269:21547-54.

Other Notes

Small volumes of anti-CHADL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CHADL purchase

MBS154377 is an antibody targeting CHADL. Also known as CHADL Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CHADL. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
chondroadherin-like protein
NCBI Official Synonym Full Names
chondroadherin like
NCBI Official Symbol
CHADL
NCBI Official Synonym Symbols
SLRR4B
UniProt Protein Name
Chondroadherin-like protein
UniProt Gene Name
CHADL
UniProt Synonym Gene Names
SLRR4B
UniProt Entry Name
CHADL_HUMAN
NCBI Protein Information
chondroadherin-like protein

UniProt Comments for CHADL

CHADL: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class IV subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 22q13.2

Cellular Component: extracellular matrix; proteinaceous extracellular matrix

Molecular Function: collagen binding

Biological Process: negative regulation of chondrocyte differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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