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UBAP2L Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS154382

The UBA domain-containing protein ubiquitin associated protein 2-like (UBAP2L), also known as NICE4, is a ubiquitously expressed 1,087 amino acid protein. UBAP2L is preferentially expressed in hematopoietic stem cell (HSC) populations and interacts with BMI1,… More details

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Product Overview

Online Datasheet in PDF
Product Name
UBAP2L, Polyclonal Antibody
Full Product Name
UBAP2L Antibody
Product Gene Name
Product Synonym Names
Ubiquitin associated protein 2-like, NICE-4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Purity/Purification
Affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Specificity
UBAP2L antibody is human and mouse reactive. At least four isoforms of UBAP2L are known to exist; this antibody will detect all four isoforms. This antibody is predicted to not cross-react with UBAP2.
Preparation and Storage
Store at 4 degree C for three months and -20 degree C, stable for up to one year.
Antibody/Peptide Pairs
UBAP2L peptide (MBS154411) is used for blocking the activity of UBAP2L antibody (MBS154382)
Molecular Weight
Predicted: 120 kDa
Observed: 130 kDa
OMIM
616472
3D Structure
ModBase 3D Structure for Q14157
Immunogen
UBAP2L antibody was raised against a 19 amino acid peptide from near the amino terminus of human UBAP2L.
Buffer
Supplied in PBS containing 0.02% sodium azide.
Positive Control 1
HeLa Cell Lysate
Conjugate
Unconjugated

Product Categories/Family for anti-UBAP2L antibody

Applications Tested/Suitable for anti-UBAP2L antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
Application Notes for anti-UBAP2L antibody
UBAP2L antibody can be used for the detection of UBAP2L by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunocytochemistry at 10 mug/ml.

Western Blot (WB) of anti-UBAP2L antibody

Western blot analysis of UBAP2L in HeLa cell lysate with UBAP2L antibody at 1 μg/ml.
Rabbit Anti-UBAP2L Polyclonal Antibody – Cat# MBS154382

Immunocytochemistry (IHC) of anti-UBAP2L antibody

Immunocytochemistry of UBAP2L in HeLa cells with UBAP2L antibody at 10 μg/ml.
Rabbit Anti-UBAP2L Polyclonal Antibody, Immunocytochemistry (IHC) – Cat# MBS154382

Immunofluorescence (IF) of anti-UBAP2L antibody

Immunofluorescence of UBAP2L in HeLa cells with UBAP2L antibody at 20 μg/ml.

Red: UBAP2L Antibody (8371)
Blue: DAPI staining
Rabbit Anti-UBAP2L Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS154382

Product References and Citations for anti-UBAP2L antibody

Bordeleau ME, Aucagne R, Chagraoui J, et al. UBAPL2L is a novel BMI1-iteracting protein essential for hematopoietic stem cell activity. Blood 2014; 124:2362-9.

Other Notes

Small volumes of anti-UBAP2L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UBAP2L purchase

MBS154382 is an antibody targeting UBAP2L. Also known as UBAP2L Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for UBAP2L. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ubiquitin-associated protein 2-like isoform a
NCBI Official Synonym Full Names
ubiquitin associated protein 2 like
NCBI Official Symbol
UBAP2L
NCBI Official Synonym Symbols
NICE4; NICE-4
UniProt Protein Name
Ubiquitin-associated protein 2-like
UniProt Synonym Protein Names
Protein NICE-4
UniProt Gene Name
UBAP2L
UniProt Synonym Gene Names
KIAA0144; NICE4
UniProt Entry Name
UBP2L_HUMAN
NCBI Protein Information
ubiquitin-associated protein 2-like

UniProt Comments for UBAP2L

NICE-4: a ubiquitous protein containing an UBA-domain, which are present in multiple proteins of the ubiquitination pathway. Encoded by a gene of the human epidermal differentiation complex (EDC). May be involved in epidermal differentiation. Three isoforms of the human protein are produced by alternative splicing.

Protein type: Ubiquitin conjugating system; RNA-binding

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: PcG protein complex

Molecular Function: protein binding

Biological Process: binding of sperm to zona pellucida
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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