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TRIM58 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS154453

TRIM58 Antibody: TRIM58 is a member of the tripartite motif-containing family of proteins that frequently possess E3 ubiquitin ligase activities (1). TRIM58 is strongly expressed in erythroid lineage cells and is further upregulated during late erythroid… More details

$530 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TRIM58, Polyclonal Antibody
Full Product Name
TRIM58 Antibody
Product Gene Name
Product Synonym Names
TRIM58 Antibody; Tripartite motif containing 58 protein; BIA2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid
Purity/Purification
Affinity chromatography purified via peptide column.
Concentration
1 mg/mL (lot specific)
Preparation and Storage
Store at 4 degree C for three months and -20 degree C, stable for up to one year.
As with all antibodies care should be taken to avoid repeated freeze thaw cycles
Antibodies should not be exposed to prolonged high temperatures.
Antibody/Peptide Pairs
TRIM58 peptide (MBS154495) is used for blocking the activity of TRIM58 antibody (MBS154453)
Molecular Weight
Predicted: 53 kDa
Observed: 56 kDa
3D Structure
ModBase 3D Structure for Q8NG06
Conjugate
Unconjugated
Immunogen
TRIM58 antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human TRIM58.
Buffer
TRIM58 Antibody is supplied in PBS containing 0.02% sodium azide.
Species
Human

Product Categories/Family for anti-TRIM58 antibody

Applications Tested/Suitable for anti-TRIM58 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-TRIM58 antibody
Western blot at 1 - 2 mug/mL.

Western Blot (WB) of anti-TRIM58 antibody

Western blot analysis of TRIM58 in (A) human heart tissue and (B) mouse kidney lysate with TRIM58 antibody at 1 μg/mL.
Rabbit Anti-TRIM58 Polyclonal Antibody – Cat# MBS154453

Product References and Citations for anti-TRIM58 antibody

1. Napolitano LM and Meroni G. TRIM family: Pleiotropy and diversification through homomultimer and heteromultimer formation. IUBMB Life 2012; 64:64-71. 2. Thom CS, Traxler EA, Khandros E, et al. Trim58 degrades dynein and regulates terminal erythropoiesis. Dev. Cell 2014; 30:688-700.

Other Notes

Small volumes of anti-TRIM58 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRIM58 purchase

MBS154453 is an antibody targeting TRIM58. Also known as TRIM58 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TRIM58. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
E3 ubiquitin-protein ligase TRIM58
NCBI Official Synonym Full Names
tripartite motif containing 58
NCBI Official Symbol
TRIM58
NCBI Official Synonym Symbols
BIA2
UniProt Protein Name
E3 ubiquitin-protein ligase TRIM58
UniProt Synonym Protein Names
Protein BIA2; RING-type E3 ubiquitin transferase TRIM58Curated; Tripartite motif-containing protein 58
UniProt Gene Name
TRIM58
NCBI Protein Information
E3 ubiquitin-protein ligase TRIM58

UniProt Comments for TRIM58

TRIM58: Belongs to the TRIM/RBCC family.

Protein type: Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 1q44

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-TRIM58 antibody

Organs/Tissues associated with anti-TRIM58 antibody

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