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Daratumumab Antibody – Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS156244

Daratumumab is a human monoclonal antibody that targets CD38, a cell surface protein that is overexpressed on multiple myeloma (MM) cells. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Daratumumab, Monoclonal Antibody
Full Product Name
Daratumumab
Product Synonym Names
HuMax-CD38; CD38
Clonality
Monoclonal
Isotype
IgG1-kappa
Species Reactivity
Homo sapiens
Form/Format
PBS buffer PH7.5
Purity/Purification
>95%
Concentration
1mg/ml (lot specific)
Specificity
Specificity target name;species CD38[Homo sapiens]
Preparation and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Molecular Weight
148000.00 Da
CAS Number
945721-28-8
Activity in vitro
Daratumumab was studied in a series of in vitro assays and was found to induce CDC in freshly isolated MM cells obtained from the bone marrow of 13 previously untreated or relapsed MM patients. Furthermore, daratumumab triggered antibodydependent cell-mediated cytotoxicity (ADCC) in CD38-expressing MM cell lines in peripheral blood mononuclear cells (PBMCs) enriched for NK cells, as well as in patient MM cells in the presence of both autologous and allogeneic effector cells.

Product Categories/Family for anti-Daratumumab antibody

Antibody drug analogues
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

SDS-PAGE of anti-Daratumumab antibody

Anti-Daratumumab Monoclonal Antibody – Cat# MBS156244

Other Notes

Small volumes of anti-Daratumumab antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Daratumumab purchase

MBS156244 is an antibody targeting Daratumumab. Reactive in Homo sapiens.
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