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Sifalimumab (IFNA1) Antibody – Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS1563330
PROMOTIONAL PRICING: 10% OFF web price. Discount is not applicable for bulk pricing such as 5x96T or 10x96T. Discount will be applied after order has been placed

MBS1563330 is an antibody targeting IFNA1. Also known as Research Grade Sifalimumab. Reactive in Human. More details

$475 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Sifalimumab (IFNA1), Monoclonal Antibody
Full Product Name
Research Grade Sifalimumab
Product Gene Name
Product Synonym Names
MDX-1103; MEDI-545; LeIF D; Interferon alpha-1/13; IFNA1; Interferon alpha-D; IFN-alpha-1/13
Clonality
Monoclonal
Isotype
IgG1-kappa
Species Reactivity
Human
Form/Format
Liquid. PBS buffer, pH7.4
Purity/Purification
>95%; Protein A or G purified from cell culture supernatant.
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at +4 degree C short term (1-2 weeks). Store at -20 degree C 12 months. Store at -80 degree C long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Molecular Weight
21,725 Da
OMIM
147578
3D Structure
ModBase 3D Structure for P01562
Host Species
Human
CAS
1006877-41-3

Product Categories/Family for anti-IFNA1 antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-IFNA1 antibody
Research Grade Sifalimumab Biosimilar

SDS-Page of anti-IFNA1 antibody

SDS PAGE for Sifalimumab
Anti-IFNA1 Monoclonal Antibody – Cat# MBS1563330

Product References and Citations for anti-IFNA1 antibody

Additional Improvements in Clinical Response From Adjuvant Biologic Response Modifiers in Adults With Moderate to Severe Systemic Lupus Erythematosus Despite Immunosuppressive Agents: A Systematic Review and Meta-analysis, PMID: 28673504
An Update on the Management of Childhood-Onset Systemic Lupus Erythematosus, PMID: 34244988
Anifrolumab in systemic lupus erythematosus: current knowledge and future considerations, PMID: 32237942
Biologic therapy for autoimmune diseases: an update, PMID: 23557513
Biologic therapy in the idiopathic inflammatory myopathies, PMID: 31680207

Other Notes

Small volumes of anti-IFNA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IFNA1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Interferon alpha-1/13
NCBI Official Synonym Full Names
interferon, alpha 1
NCBI Official Symbol
IFNA1
NCBI Official Synonym Symbols
IFL; IFN; IFNA@; IFNA13; IFN-ALPHA; IFN-alphaD
UniProt Protein Name
Interferon alpha-1/13
UniProt Synonym Protein Names
Interferon alpha-D
Protein Family
UniProt Gene Name
IFNA1
UniProt Synonym Gene Names
IFN-alpha-1/13; LeIF D
UniProt Entry Name
IFNA1_HUMAN
NCBI Protein Information
interferon alpha-1/13; leIF D; IFN-alpha 1b; IFN-alpha-1/13; interferon-alpha1; interferon alpha-D; interferon alpha 1b

NCBI Summary for IFNA1

The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. [provided by RefSeq, Sep 2011]

UniProt Comments for IFNA1

IFNA1/13: a cytokine that belongs to the alpha/beta interferon family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 9p22

Cellular Component: extracellular space; extracellular region

Molecular Function: interferon-alpha/beta receptor binding; cytokine activity

Biological Process: B cell proliferation; adaptive immune response; cytokine and chemokine mediated signaling pathway; regulation of MHC class I biosynthetic process; humoral immune response; T cell activation during immune response; response to exogenous dsRNA; B cell differentiation; natural killer cell activation during immune response; innate immune response; blood coagulation; defense response to virus; positive regulation of peptidyl-serine phosphorylation of STAT protein
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IFNA1 antibody

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