Human IL34 Recombinant Protein – Cat# MBS157064

IL34 Human Recombinant Protein

Name: IL34 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS157064
Price: 410 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS157064

MBS157064 is a recombinant protein targeting IL34. Also known as Recombinant Human IL34 protein, C-His Tag. Host: Mammalian cells. More details

$410 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IL34, Recombinant Protein

Full Product Name

Recombinant Human IL34 protein, C-His Tag

Product Gene Name

IL34 recombinant protein

Product Synonym Names

C16orf77; Interleukin-34; IL-34; IL34

Host

Mammalian cells

Form/Format

Lyophilized. Lyophilized from PBS pH 7.4, 5% Trehalose, 5% Mannose?1mM EDTA

Purity/Purification

>90% as determined by SDS-PAGE

Preparation and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 degree C for one week. Store at -20 to -80 degree C for ~12 months from the date of receipt.
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise

Molecular Weight

27,482 Da

Chromosome Location

Chromosome: 16; NC_000016.9 (70613798..70694585). Location: 16q22.1

OMIM

612081

3D Structure

ModBase 3D Structure for Q6ZMJ4

Source

Human

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Construction

A DNA sequence encoding the Human IL34 (Met1-Pro240) was fused with the C-His Tag

Product Categories/Family for IL34 recombinant protein

Protein

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of IL34 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL34. It may not necessarily be applicable to this product.

NCBI GI #

289666752

NCBI GeneID

146433

NCBI Accession #

NP_001166243.1

UniProt Primary Accession #

Q6ZMJ4

UniProt Secondary Accession #

Q8N6L2; B2RC28; B2Z4A8; B2ZC70

UniProt Related Accession #

Q6ZMJ4

GenBank Nucleotide #

NM_001172772.1

NCBI Official Full Name

interleukin-34 isoform 1

NCBI Official Synonym Full Names

interleukin 34

NCBI Official Symbol

IL34

NCBI Official Synonym Symbols

IL-34; C16orf77

UniProt Protein Name

Interleukin-34

Protein Family

Interleukin

UniProt Gene Name

IL34

UniProt Synonym Gene Names

C16orf77; IL-34

UniProt Entry Name

IL34_HUMAN

NCBI Protein Information

interleukin-34

NCBI Summary for IL34

Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).[supplied by OMIM, May 2008]

UniProt Comments for IL34

IL34: Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Belongs to the IL-34 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted; Cell cycle regulation; Cytokine

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: extracellular space

Molecular Function: growth factor activity; cytokine activity; macrophage colony stimulating factor receptor binding

Biological Process: positive regulation of cell proliferation; innate immune response; positive regulation of protein amino acid phosphorylation; inflammatory response

Research Articles on IL34

1. the feline CSF-1R was cloned and the responsiveness to CSF-1 and IL-34 from a range of species, was examined.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IL34 recombinant protein

Reference Product	PubMed Publications
CSF1R recombinant protein	>3 publications with IL34 and CSF1R