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IL34 Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1577939

MBS1577939 is a recombinant protein targeting IL34. Also known as Recombinant Mouse IL34 Protein, C-His. Host: Mammalian. More details

$575 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL34, Recombinant Protein
Full Product Name
Recombinant Mouse IL34 Protein, C-His
Product Gene Name
IL34 recombinant protein
Product Synonym Names
Interleukin-34; IL-34; Il34
Host
Mammalian
Form/Format
Lyophilized from a solution in PBS pH7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Purity/Purification
>90% as determined by SDS-PAGE
Preparation and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 degree C for one week. Store at -20 degree C for twelve months from the date of receipt.
Molecular Weight
26,636 Da
Sequence Positions
Asn21-Pro235
3D Structure
ModBase 3D Structure for Q8R1R4
Species
Mouse
Reconstitution
Reconstitute in sterile water for a stock solution.

Product Categories/Family for IL34 recombinant protein

Recombinant Proteins
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for IL34 recombinant protein
SDS-PAGE (SDS), Western Blot (WB), ELISA (EIA), Immunogen

Other Notes

Small volumes of IL34 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL34. It may not necessarily be applicable to this product.

NCBI GI #
205360952
NCBI GeneID
76527
NCBI Accession #
NP_001128572.1
UniProt Primary Accession #
Q8R1R4
UniProt Secondary Accession #
Q9D8F2; B2ZC71; B2ZC72
UniProt Related Accession #
Q8R1R4
GenBank Nucleotide #
NM_001135100.2
NCBI Official Full Name
interleukin-34 isoform 1
NCBI Official Synonym Full Names
interleukin 34
NCBI Official Symbol
Il34
NCBI Official Synonym Symbols
AI593503; 2010004A03Rik
UniProt Protein Name
Interleukin-34
Protein Family
Interleukin
UniProt Gene Name
Il34
UniProt Synonym Gene Names
IL-34
UniProt Entry Name
IL34_MOUSE
NCBI Protein Information
interleukin-34

UniProt Comments for IL34

IL34: Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Belongs to the IL-34 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Cytokine; Secreted; Secreted, signal peptide

Cellular Component: extracellular space

Molecular Function: macrophage colony stimulating factor receptor binding

Biological Process: positive regulation of cell proliferation; positive regulation of macrophage differentiation; positive regulation of monocyte differentiation; positive regulation of protein amino acid phosphorylation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with IL34 recombinant protein

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >3 publications with IL34 and Necrosis
 Inflammation Antibodies  >3 publications with IL34 and Inflammation
 Diabetes Mellitus Antibodies  >2 publications with IL34 and Diabetes Mellitus

Organs/Tissues associated with IL34 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >4 publications with IL34 and Bone
 Embryonic Tissue Antibodies  >3 publications with IL34 and Embryonic Tissue
 Skin Antibodies  >2 publications with IL34 and Skin
 Brain Antibodies  >2 publications with IL34 and Brain
 Intestine Antibodies  >1 publications with IL34 and Intestine
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