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HBV S/L-Hbsag/L Glycoprotein (HBV) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1576142

MBS1576142 is a recombinant protein targeting HBV. Also known as Recombinant HBV S/L-HBsAg/L glycoprotein Protein, C-S Tag. Host: Mammalian. More details

$575 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HBV S/L-HBsAg/L glycoprotein, Recombinant Protein
Full Product Name
Recombinant HBV S/L-HBsAg/L glycoprotein Protein, C-S Tag
Product Gene Name
Product Synonym Names
Large envelope protein; L glycoprotein; L-HBsAg; LHB; Large S protein; Large surface protein; Major surface antigen; S; Hepatitis B Virus (HBV)
Host
Mammalian
Form/Format
Lyophilized from a solution in PBS pH7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Purity/Purification
>90% as determined by SDS-PAGE
Preparation and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 degree C for one week. Store at -20 to -80 degree C for twelve months from the date of receipt.
Molecular Weight
25,320 Da
Sequence Positions
Met175-Ile400
3D Structure
ModBase 3D Structure for Q9E6S4
Species
Hepatitis C virus genotype 1a (isolate H77)(HCV)
Reconstitution
Reconstitute in sterile water for a stock solution.

Product Categories/Family for HBV recombinant protein

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for HBV recombinant protein
SDS-PAGE (SDS), Western Blot (WB), ELISA (EIA), Immunogen

SDS-Page of HBV recombinant protein

SDS PAGE for recombinant Hepatitis B virus S/L-HBsAg/L glycoprotein
HBV Recombinant Protein – Cat# MBS1576142

Bioactivity of HBV recombinant protein

Detects Exbivirumab in indirect ELISAs.
HBV Recombinant Protein, Bioactivity – Cat# MBS1576142

Bioactivity of HBV recombinant protein

Detects Libivirumab in indirect ELISAs.
HBV Recombinant Protein, Bioactivity – Cat# MBS1576142

Product References and Citations for HBV recombinant protein

Bulevirtide monotherapy for 48 weeks in patients with HDV-related compensated cirrhosis and clinically significant portal hypertension. PMID: 35973578
Skin immunization with third-generation hepatitis B surface antigen using microneedles. PMID: 31466705
Phosphorylation of the Hepatitis B Virus Large Envelope Protein. PMID: 35282608
Characterization of HBV surface antigen isoforms in the natural history and treatment of HBV infection. PMID: 37026760
HBsAg loading on dendritic cells in patients with chronic hepatitis B: expressions of phenotypic molecules. PMID: 16481284

Other Notes

Small volumes of HBV recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HBV. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
NCBI Official Full Name
Large envelope protein
UniProt Protein Name
Large envelope protein
UniProt Synonym Protein Names
L glycoprotein; L-HBsAg; LHB; Large S protein; Large surface protein; Major surface antigen
UniProt Gene Name
S
UniProt Synonym Gene Names
LHB
UniProt Entry Name
HBSAG_HBVC0

UniProt Comments for HBV

The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assumes fusion between virion membrane and endosomal membrane (Probable). In its internal conformation the protein plays a role in virion morphogenesis and mediates the contact with the nucleocapsid like a matrix protein ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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