Human CK-MB Recombinant Protein – Cat# MBS1577694

SDS PAGE for Recombinant Human CK-MB protein

CK-MB Human Recombinant Protein

Name: CK-MB Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1577694
Price: 465 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1577694

MBS1577694 is a recombinant protein targeting CK-MB. Also known as Recombinant Human CK-MB Protein, N-His & C-Strep. Host: E coli. More details

$465 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CK-MB, Recombinant Protein

Full Product Name

Recombinant Human CK-MB Protein, N-His & C-Strep

Product Gene Name

CK-MB recombinant protein

Product Synonym Names

Creatine kinase M-type; 2.7.3.2; Creatine kinase M chain; Creatine phosphokinase M-type; CPK-M; M-CK; CKM; CKMM; Creatine kinase B-type; 2.7.3.2; Brain creatine kinase; B-CK; Creatine kinase B chain; Creatine phosphokinase B-type; CPK-B; CKB; CKBB; CKMB; CK-MB

Host

E coli

Form/Format

Lyophilized from a solution in PBS pH7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Purity/Purification

>90% as determined by SDS-PAGE

Preparation and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 degree C for one week. Store at -20 to -80 degree C for twelve months from the date of receipt.

Molecular Weight

43,101 Da

Sequence Positions

CKM [Met1-Lys381] & CKB [Met1-Lys381]

Chromosome Location

Chromosome: 19; NC_000019.9 (45809671..45826235, complement). Location: 19q13.32

OMIM

123310

3D Structure

ModBase 3D Structure for P06732

Species

Human

Reconstitution

Reconstitute in sterile water for a stock solution.

Product Categories/Family for CK-MB recombinant protein

Recombinant Proteins

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for CK-MB recombinant protein

SDS-PAGE (SDS), Western Blot (WB), ELISA (EIA), Immunogen

Other Notes

Small volumes of CK-MB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CK-MB. It may not necessarily be applicable to this product.

NCBI GI #

21536288

NCBI GeneID

1158

NCBI Accession #

NP_001815.2

UniProt Primary Accession #

P06732

UniProt Secondary Accession #

P12277

UniProt Related Accession #

P06732

GenBank Nucleotide #

NM_001824.4

NCBI Official Full Name

creatine kinase M-type

NCBI Official Synonym Full Names

creatine kinase, muscle

NCBI Official Symbol

CKM

NCBI Official Synonym Symbols

CKMM; M-CK

UniProt Protein Name

Creatine kinase M-type

UniProt Synonym Protein Names

Creatine kinase M chain; M-CK

UniProt Gene Name

CKM

UniProt Synonym Gene Names

CKMM

UniProt Entry Name

KCRM_HUMAN

NCBI Protein Information

creatine kinase M-type; creatine kinase M chain

NCBI Summary for CK-MB

The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008]

UniProt Comments for CK-MB

CKM: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Belongs to the ATP:guanido phosphotransferase family.

Protein type: EC 2.7.3.2; Kinase, other; Amino Acid Metabolism - arginine and proline

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: cytosol

Molecular Function: creatine kinase activity; ATP binding

Biological Process: phosphocreatine biosynthetic process; phosphorylation; creatine metabolic process

Research Articles on CK-MB

1. The current enzymatic definition of procedural myocardial infarct (MI) (CK-myocardial band more than 3 times the upper limit of normal) used in clinical trials is less strongly associated with death than that of spontaneous MI.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CK-MB recombinant protein

Reference Product	PubMed Publications
CKB recombinant protein	>13 publications with CK-MB and CKB

Pathways associated with CK-MB recombinant protein

Products by Pathway	Pathway Diagram
Arginine And Proline Metabolism Pathway antibodies	Arginine And Proline Metabolism Pathway Diagram
Arginine And Proline Metabolism Pathway antibodies	Arginine And Proline Metabolism Pathway Diagram
Creatine Metabolism Pathway antibodies	Creatine Metabolism Pathway Diagram
Creatine Pathway antibodies	Creatine Pathway Diagram
Creatine Pathway antibodies	Creatine Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Amino Acids And Derivatives Pathway antibodies	Metabolism Of Amino Acids And Derivatives Pathway Diagram
Regulation Of Retinoblastoma Protein Pathway antibodies	Regulation Of Retinoblastoma Protein Pathway Diagram
Urea Cycle And Metabolism Of Amino Groups Pathway antibodies	Urea Cycle And Metabolism Of Amino Groups Pathway Diagram
Creatine-phosphate Biosynthesis Pathway antibodies	Creatine-phosphate Biosynthesis Pathway Diagram

Diseases associated with CK-MB recombinant protein

Disease Name	Pubmed Publications
Neoplasms Antibodies	>12 publications with CK-MB and Neoplasms
Heart Diseases Antibodies	>11 publications with CK-MB and Heart Diseases
Myocardial Infarction Antibodies	>6 publications with CK-MB and Myocardial Infarction
Kidney Diseases Antibodies	>5 publications with CK-MB and Kidney Diseases
Lung Neoplasms Antibodies	>4 publications with CK-MB and Lung Neoplasms
Ischemia Antibodies	>4 publications with CK-MB and Ischemia
Cardiomyopathies Antibodies	>3 publications with CK-MB and Cardiomyopathies
Liver Diseases Antibodies	>3 publications with CK-MB and Liver Diseases
Brain Diseases Antibodies	>3 publications with CK-MB and Brain Diseases
Neoplasm Metastasis Antibodies	>3 publications with CK-MB and Neoplasm Metastasis

Organs/Tissues associated with CK-MB recombinant protein

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>46 publications with CK-MB and Muscle
Heart Antibodies	>24 publications with CK-MB and Heart
Brain Antibodies	>8 publications with CK-MB and Brain
Kidney Antibodies	>7 publications with CK-MB and Kidney
Lung Antibodies	>6 publications with CK-MB and Lung
Liver Antibodies	>6 publications with CK-MB and Liver
Embryonic Tissue Antibodies	>3 publications with CK-MB and Embryonic Tissue
Vascular Antibodies	>3 publications with CK-MB and Vascular
Nerve Antibodies	>2 publications with CK-MB and Nerve
Eye Antibodies	>2 publications with CK-MB and Eye