Human RBM38 Recombinant Protein – Cat# MBS157694

RBM38 Human Recombinant Protein

Name: RBM38 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS157694
Price: 385 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS157694

MBS157694 is a recombinant protein targeting RBM38. Also known as Recombinant Human RBM38 protein, N- GST Tag. Host: E Coli. More details

$385 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RBM38, Recombinant Protein

Full Product Name

Recombinant Human RBM38 protein, N- GST Tag

Product Gene Name

RBM38 recombinant protein

Product Synonym Names

CLL-associated antigen KW-5; HSRNASEB; RNA-binding motif protein 38; RNA-binding region-containing protein 1; ssDNA-binding protein SEB4; RNPC1; SEB4

Host

E Coli

Form/Format

Lyophilized. Lyophilized from in PBS, pH 7.5, 4M urea, 5% Trehalose, 5% Mannose, 1mM EDTA.

Purity/Purification

>90% as determined by SDS-PAGE

Preparation and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 degree C for one week. Store at -20 to -80 degree C for ~12 months from the date of receipt.
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
In general, proteins are provided as lyophilized powder. They are shipped out with blue ice unless customers require otherwise

Molecular Weight

12,914 Da

3D Structure

ModBase 3D Structure for Q9H0Z9

Source

Human

Construction

A DNA sequence encoding the Human RBM38 (Thr132-Gln239) was fused with the N-terminal GST Tag

Product Categories/Family for RBM38 recombinant protein

Protein

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of RBM38 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RBM38. It may not necessarily be applicable to this product.

NCBI GI #

34577107

NCBI GeneID

55544

NCBI Accession #

NP_059965.2

UniProt Primary Accession #

Q9H0Z9

UniProt Secondary Accession #

Q15350; Q15351; Q9BYK3; Q9BYK4; A6NDK1; A6NMU6

UniProt Related Accession #

Q9H0Z9

GenBank Nucleotide #

NM_017495.5

NCBI Official Full Name

RNA-binding protein 38 isoform a

NCBI Official Synonym Full Names

RNA binding motif protein 38

NCBI Official Symbol

RBM38

NCBI Official Synonym Symbols

RNPC1; SEB4B; SEB4D; HSRNASEB; dJ800J21.2

UniProt Protein Name

RNA-binding protein 38

UniProt Synonym Protein Names

CLL-associated antigen KW-5; HSRNASEB; RNA-binding motif protein 38; RNA-binding region-containing protein 1; ssDNA-binding protein SEB4

Protein Family

RNA-binding protein

UniProt Gene Name

RBM38

UniProt Synonym Gene Names

RNPC1; SEB4

NCBI Protein Information

RNA-binding protein 38

UniProt Comments for RBM38

RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.

Research Articles on RBM38

1. Investigated RNA-binding region-containing protein 1 (RNPC1) action on signal pathways and disease progression in lung cancer samples and cells. Found RNPC1 acts to downregulate the miR-181a mediated inhibition of cancer susceptibility 2 (CASC2) expression in lung cancer. Results show RNPC1 inhibits NSCLC progression in a miR-181a/CASC2 axis-dependent manner.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with RBM38 recombinant protein

Disease Name	Pubmed Publications
Neoplasms Antibodies	>2 publications with RBM38 and Neoplasms
Cardiovascular Diseases Antibodies	>1 publications with RBM38 and Cardiovascular Diseases
Nervous System Malformations Antibodies	>1 publications with RBM38 and Nervous System Malformations
Adenocarcinoma Antibodies	>1 publications with RBM38 and Adenocarcinoma
Neural Tube Defects Antibodies	>1 publications with RBM38 and Neural Tube Defects
Congenital Abnormalities Antibodies	>1 publications with RBM38 and Congenital Abnormalities

Organs/Tissues associated with RBM38 recombinant protein

Organ/Tissue Name	Pubmed Publications
Heart Antibodies	>1 publications with RBM38 and Heart
Muscle Antibodies	>1 publications with RBM38 and Muscle