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TUBA1B/Alpha Tubulin (TUBA1B) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1578604

MBS1578604 is a recombinant protein targeting TUBA1B. Also known as Recombinant Human TUBA1B/Alpha Tubulin Protein, C-His. Host: E coli. More details

$435 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TUBA1B/Alpha Tubulin, Recombinant Protein
Full Product Name
Recombinant Human TUBA1B/Alpha Tubulin Protein, C-His
Product Gene Name
TUBA1B recombinant protein
Product Synonym Names
Tubulin alpha-ubiquitous chain; Tubulin alpha-1B chain; Alpha-tubulin ubiquitous; Tubulin K-alpha-1; TUBA1B
Host
E coli
Form/Format
Lyophilized from a solution in PBS pH7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Purity/Purification
>90% as determined by SDS-PAGE
Preparation and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 degree C for one week. Store at -20 degree C for twelve months from the date of receipt.
Molecular Weight
37,218 Da
Sequence Positions
Met1-Tyr451
OMIM
602530
3D Structure
ModBase 3D Structure for P68363
Species
Human
Reconstitution
Reconstitute in sterile water for a stock solution.

Product Categories/Family for TUBA1B recombinant protein

Recombinant Proteins
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for TUBA1B recombinant protein
SDS-PAGE (SDS), Western Blot (WB), ELISA (EIA), Immunogen

Other Notes

Small volumes of TUBA1B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TUBA1B. It may not necessarily be applicable to this product.

NCBI GI #
55977474
NCBI GeneID
10376
NCBI Accession #
P68363.1
UniProt Primary Accession #
P68363
UniProt Secondary Accession #
P04687; P05209; Q27I68; Q8WU19
UniProt Related Accession #
P68363
NCBI Official Full Name
Tubulin alpha-1B chain
NCBI Official Synonym Full Names
tubulin, alpha 1b
NCBI Official Symbol
TUBA1B
NCBI Official Synonym Symbols
K-ALPHA-1
UniProt Protein Name
Tubulin alpha-1B chain
UniProt Synonym Protein Names
Alpha-tubulin ubiquitous; Tubulin K-alpha-1; Tubulin alpha-ubiquitous chain
UniProt Gene Name
TUBA1B
UniProt Entry Name
TBA1B_HUMAN
NCBI Protein Information
tubulin alpha-1B chain; alpha tubulin; tubulin K-alpha-1; alpha-tubulin ubiquitous; tubulin, alpha, ubiquitous; tubulin alpha-ubiquitous chain

UniProt Comments for TUBA1B

TUBA1B: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Dimer of alpha and beta chains. Belongs to the tubulin family.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 12q13.12

Cellular Component: microtubule; cytoplasmic microtubule

Molecular Function: GTPase activity; protein binding; GTP binding; structural constituent of cytoskeleton; ubiquitin protein ligase binding; double-stranded RNA binding; structural molecule activity

Biological Process: protein polymerization; 'de novo' posttranslational protein folding; cellular protein metabolic process; protein folding; cell division; cytoskeleton-dependent intracellular transport; microtubule cytoskeleton organization and biogenesis; microtubule-based process
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Research Articles on TUBA1B

1. Data indicate that the derivatives exhibited much better potency to inhibit tubulin polymerization but a decreased activity to inhibit Hsp27 chaperone function.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with TUBA1B recombinant protein

 Products by Pathway  Pathway Diagram
 Chaperonin-mediated Protein Folding Pathway antibodies  Chaperonin-mediated Protein Folding Pathway Diagram
 Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway antibodies  Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway Diagram
 Formation Of Tubulin Folding Intermediates By CCT/TriC Pathway antibodies  Formation Of Tubulin Folding Intermediates By CCT/TriC Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Parkin-Ubiquitin Proteasomal System Pathway antibodies  Parkin-Ubiquitin Proteasomal System Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram
 Pathogenic Escherichia Coli Infection Pathway antibodies  Pathogenic Escherichia Coli Infection Pathway Diagram

Diseases associated with TUBA1B recombinant protein

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >3 publications with TUBA1B and Nervous System Diseases
 Liver Diseases Antibodies  >1 publications with TUBA1B and Liver Diseases
 Optic Nerve Diseases Antibodies  >1 publications with TUBA1B and Optic Nerve Diseases
 Brain Diseases Antibodies  >1 publications with TUBA1B and Brain Diseases

Organs/Tissues associated with TUBA1B recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >3 publications with TUBA1B and Eye
 Liver Antibodies  >2 publications with TUBA1B and Liver
 Brain Antibodies  >2 publications with TUBA1B and Brain
 Nerve Antibodies  >1 publications with TUBA1B and Nerve
 Heart Antibodies  >1 publications with TUBA1B and Heart
 Ovary Antibodies  >1 publications with TUBA1B and Ovary
 Testis Antibodies  >1 publications with TUBA1B and Testis
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