Intercellular Adhesion Molecule 1, Sicam-1 (sICAM-1) ELISA Kit for Rat

Name: Rat sICAM-1 ELISA Kit; Intercellular Adhesion Molecule 1, Sicam-1; MyBioSource
Brand: MyBioSource
SKU: MBS160245
Price: 445 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS160245

Principle of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with Rat sICAM-1 antibody. sICAM-1 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Rat sICAM-1… More details

$445 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Intercellular Adhesion Molecule 1, sICAM-1, ELISA Kit

Full Product Name

Rat Soluble Intercellular Adhesion Molecule 1, sICAM-1 ELISA Kit

Product Gene Name

sICAM-1 elisa kit

Species Reactivity

Rat

Assay Type

Quantitative Sandwich

Samples

Serum, plasma, cell culture supernates, Ascites, tissue homogenates or other biological fluids

Detection Range

0.05-20ng/ml

Sensitivity

0.026ng/ml

Preparation and Storage

Store at 2 to 8 degree C for 6 months.

Inter-assay Precision

Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision. CV(%) = SD/mean x 100. Inter-Assay: CV<10%

Intra-assay Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision. Intra-Assay: CV<8%

Molecular Weight

57,825 Da

3D Structure

ModBase 3D Structure for P05362

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of sICAM-1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for sICAM-1 purchase

MBS160245 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Intercellular Adhesion Molecule 1, sICAM-1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing sICAM-1. The ELISA analytical biochemical technique of the MBS160245 kit is based on sICAM-1 antibody-sICAM-1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect sICAM-1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, sICAM-1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for sICAM-1. It may not necessarily be applicable to this product.

NCBI GI #

1836075

NCBI GeneID

3383

NCBI Accession #

AAB46863.1

UniProt Primary Accession #

P05362

UniProt Secondary Accession #

Q5NKV7; Q96B50; B2R6M3

UniProt Related Accession #

P05362

NCBI Official Full Name

sICAM-1, partial

NCBI Official Synonym Full Names

intercellular adhesion molecule 1

NCBI Official Symbol

ICAM1

NCBI Official Synonym Symbols

BB2; CD54; P3.58

UniProt Protein Name

Intercellular adhesion molecule 1

UniProt Synonym Protein Names

Major group rhinovirus receptor; CD_antigen: CD54

UniProt Gene Name

ICAM1

UniProt Synonym Gene Names

ICAM-1

NCBI Protein Information

intercellular adhesion molecule 1

NCBI Summary for sICAM-1

This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]

UniProt Comments for sICAM-1

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.

Research Articles on sICAM-1

1. Serum CCL2 and sICAM-1 concentrations were significantly decreased in CNS tumors in comparison with the comparative group. Among proteins tested in the serum, a higher area under the ROC curve (AUC) revealed CCL2 compared to sICAM-1 in differentiating subjects with CNS brain tumors from non-tumoral subjects.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with sICAM-1 elisa kit

Reference Product	PubMed Publications
ITGB2 elisa kit	>860 publications with sICAM-1 and ITGB2
ITGAL elisa kit	>467 publications with sICAM-1 and ITGAL
ITGAM elisa kit	>423 publications with sICAM-1 and ITGAM
CD44 elisa kit	>356 publications with sICAM-1 and CD44
ITGAX elisa kit	>134 publications with sICAM-1 and ITGAX
IL6 elisa kit	>115 publications with sICAM-1 and IL6
SELE elisa kit	>59 publications with sICAM-1 and SELE
HLA-B elisa kit	>28 publications with sICAM-1 and HLA-B
DIF elisa kit	>3 publications with sICAM-1 and DIF

Pathways associated with sICAM-1 elisa kit

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
African Trypanosomiasis Pathway antibodies	African Trypanosomiasis Pathway Diagram
African Trypanosomiasis Pathway antibodies	African Trypanosomiasis Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Epstein-Barr Virus Infection Pathway antibodies	Epstein-Barr Virus Infection Pathway Diagram
Epstein-Barr Virus Infection Pathway antibodies	Epstein-Barr Virus Infection Pathway Diagram
Glucocorticoid Receptor Regulatory Network Pathway antibodies	Glucocorticoid Receptor Regulatory Network Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram

Diseases associated with sICAM-1 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>5053 publications with sICAM-1 and Inflammation
Necrosis Antibodies	>4428 publications with sICAM-1 and Necrosis
Cardiovascular Diseases Antibodies	>3292 publications with sICAM-1 and Cardiovascular Diseases
Atherosclerosis Antibodies	>1304 publications with sICAM-1 and Atherosclerosis
Reperfusion Injury Antibodies	>809 publications with sICAM-1 and Reperfusion Injury
Myocardial Ischemia Antibodies	>738 publications with sICAM-1 and Myocardial Ischemia
Kidney Diseases Antibodies	>717 publications with sICAM-1 and Kidney Diseases
Liver Diseases Antibodies	>511 publications with sICAM-1 and Liver Diseases
Asthma Antibodies	>473 publications with sICAM-1 and Asthma
Hypertension Antibodies	>472 publications with sICAM-1 and Hypertension

Organs/Tissues associated with sICAM-1 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>11046 publications with sICAM-1 and Blood
Vascular Antibodies	>8209 publications with sICAM-1 and Vascular
Lung Antibodies	>1629 publications with sICAM-1 and Lung
Heart Antibodies	>1176 publications with sICAM-1 and Heart
Skin Antibodies	>1165 publications with sICAM-1 and Skin
Liver Antibodies	>1106 publications with sICAM-1 and Liver
Kidney Antibodies	>1097 publications with sICAM-1 and Kidney
Brain Antibodies	>1084 publications with sICAM-1 and Brain
Muscle Antibodies	>955 publications with sICAM-1 and Muscle
Embryonic Tissue Antibodies	>754 publications with sICAM-1 and Embryonic Tissue