Heme Oxygenase 2, Ho-2 (HO-2) ELISA Kit for Rat

Name: Rat HO-2 ELISA Kit; Heme Oxygenase 2, Ho-2; MyBioSource
Brand: MyBioSource
SKU: MBS161534
Price: 445 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS161534

Intended Uses: This sandwich kit is for the accurate quantitative detection of Rat Heme Oxygenase 2 (also known as HO-2) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.Principles of the Assay: This kit is an Enzyme-Linked… More details

$445 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

heme oxygenase 2, HO-2, ELISA Kit

Full Product Name

Rat heme oxygenase 2, HO-2 ELISA Kit

Product Gene Name

HO-2 elisa kit

Species Reactivity

Rat

Assay Type

Quantitative Sandwich

Samples

Serum, plasma, cell culture supernates, cell lysates, tissue homogenates

Detection Range

0.1ng/ml - 30ng/ml

Sensitivity

0.04ng/ml

Preparation and Storage

Store at 2 to 8 degree C for 6 months.

Molecular Weight

32,837 Da

3D Structure

ModBase 3D Structure for P30519

Intra-Assay

CV<8%

Inter-Assay

CV<10%

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of HO-2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HO-2 purchase

MBS161534 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the heme oxygenase 2, HO-2, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HO-2. The ELISA analytical biochemical technique of the MBS161534 kit is based on HO-2 antibody-HO-2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HO-2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HO-2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for HO-2. It may not necessarily be applicable to this product.

NCBI GI #

8051608

NCBI GeneID

3163

NCBI Accession #

NP_002125.3

UniProt Primary Accession #

P30519

UniProt Secondary Accession #

O60605; A8MT35; D3DUD5; I3L430

UniProt Related Accession #

P30519

GenBank Nucleotide #

NM_002134.3

NCBI Official Full Name

heme oxygenase 2 isoform b

NCBI Official Synonym Full Names

heme oxygenase 2

NCBI Official Symbol

HMOX2

NCBI Official Synonym Symbols

HO-2

UniProt Protein Name

Heme oxygenase 2

UniProt Gene Name

HMOX2

UniProt Synonym Gene Names

HO2; HO-2

NCBI Protein Information

heme oxygenase 2

NCBI Summary for HO-2

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Several alternatively spliced transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]

UniProt Comments for HO-2

Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.

Research Articles on HO-2

1. The frequencies of genotype and allelic variants of ALAD rs1800435 did not differ significantly between patients with essential tremor (ET) and controls, and were not influenced by gender. Subjects carrying the ALAD rs1800435CC genotype (wild-type) and the HMOX2 rs1051308GG genotype or the HMOX2 rs1051308G allele had significantly decreased risk for ET.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HO-2 elisa kit

Reference Product	PubMed Publications
BLVRA elisa kit	>1 publications with HO-2 and BLVRA

Pathways associated with HO-2 elisa kit

Products by Pathway	Pathway Diagram
Heme Degradation Pathway antibodies	Heme Degradation Pathway Diagram
Iron Uptake And Transport Pathway antibodies	Iron Uptake And Transport Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Porphyrins Pathway antibodies	Metabolism Of Porphyrins Pathway Diagram
Mineral Absorption Pathway antibodies	Mineral Absorption Pathway Diagram
Mineral Absorption Pathway antibodies	Mineral Absorption Pathway Diagram
Porphyrin And Chlorophyll Metabolism Pathway antibodies	Porphyrin And Chlorophyll Metabolism Pathway Diagram
Porphyrin And Chlorophyll Metabolism Pathway antibodies	Porphyrin And Chlorophyll Metabolism Pathway Diagram
Transmembrane Transport Of Small Molecules Pathway antibodies	Transmembrane Transport Of Small Molecules Pathway Diagram
Heme Degradation Pathway antibodies	Heme Degradation Pathway Diagram

Diseases associated with HO-2 elisa kit

Disease Name	Pubmed Publications
Brain Diseases Antibodies	>2 publications with HO-2 and Brain Diseases
Nervous System Diseases Antibodies	>2 publications with HO-2 and Nervous System Diseases
Drug Toxicity Antibodies	>2 publications with HO-2 and Drug Toxicity
Inflammation Antibodies	>2 publications with HO-2 and Inflammation
Seizures Antibodies	>1 publications with HO-2 and Seizures
Cardiovascular Diseases Antibodies	>1 publications with HO-2 and Cardiovascular Diseases
Hypertension Antibodies	>1 publications with HO-2 and Hypertension
Fatty Liver Antibodies	>1 publications with HO-2 and Fatty Liver
Necrosis Antibodies	>1 publications with HO-2 and Necrosis

Organs/Tissues associated with HO-2 elisa kit

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>3 publications with HO-2 and Liver
Blood Antibodies	>2 publications with HO-2 and Blood
Ear Antibodies	>1 publications with HO-2 and Ear
Muscle Antibodies	>1 publications with HO-2 and Muscle
Eye Antibodies	>1 publications with HO-2 and Eye
Skin Antibodies	>1 publications with HO-2 and Skin
Testis Antibodies	>1 publications with HO-2 and Testis
Brain Antibodies	>1 publications with HO-2 and Brain