Porcine IGF-2 ELISA Kit – Cat# MBS161788

Insulin-Like Growth Factors 2, IGF-2 (IGF-2) ELISA Kit for Porcine

Name: Porcine IGF-2 ELISA Kit; Insulin-Like Growth Factors 2, IGF-2; MyBioSource
Brand: MyBioSource
SKU: MBS161788
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS161788

Intended Uses: This sandwich kit is for the accurate quantitative detection of Porcine Insulin-like Growth Factors 2 (also known as IGF-2) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.Principles of the Assay: This kit is an… More details

$520 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

insulin-like growth factors 2, IGF-2, ELISA Kit

Full Product Name

Porcine insulin-like growth factors 2, IGF-2 ELISA Kit

Product Gene Name

IGF-2 elisa kit

Species Reactivity

Porcine

Assay Type

Quantitative Sandwich

Samples

Serum, plasma, cell culture supernates, cell lysates, tissue homogenates

Detection Range

40ng/ml - 3000ng/ml

Sensitivity

22.62ng/ml

Preparation and Storage

Store at 2 to 8 degree C for 6 months.

Molecular Weight

21,061 Da

3D Structure

ModBase 3D Structure for P09535

Intra-Assay

CV<8%

Inter-Assay

CV<10%

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of IGF-2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IGF-2 purchase

MBS161788 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the insulin-like growth factors 2, IGF-2, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IGF-2. The ELISA analytical biochemical technique of the MBS161788 kit is based on IGF-2 antibody-IGF-2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IGF-2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IGF-2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for IGF-2. It may not necessarily be applicable to this product.

NCBI GI #

298231180

NCBI GeneID

16002

NCBI Accession #

NP_034644.2

UniProt Primary Accession #

P09535

UniProt Secondary Accession #

E9QLW5

UniProt Related Accession #

P09535

GenBank Nucleotide #

NM_010514.3

NCBI Official Full Name

insulin-like growth factor II isoform 1

NCBI Official Synonym Full Names

insulin-like growth factor 2

NCBI Official Symbol

Igf2

NCBI Official Synonym Symbols

Mpr; M6pr; Peg2; Igf-2; Igf-II; AL033362

UniProt Protein Name

Insulin-like growth factor II

UniProt Synonym Protein Names

IGF-II; Multiplication-stimulating polypeptide

UniProt Gene Name

Igf2

UniProt Synonym Gene Names

Igf-2

NCBI Protein Information

insulin-like growth factor II

NCBI Summary for IGF-2

This gene encodes a member of the insulin-like growth factor (IGF) family of proteins that promote growth and development during fetal and postnatal life. It is an imprinted gene that is expressed only from the paternal allele. The encoded protein undergoes proteolytic processing to generate a mature peptide. The transgenic overexpression of this gene in mice results in prenatal overgrowth, polyhydramnios, fetal and neonatal lethality, disproportionate organ overgrowth including tongue enlargement, and skeletal abnormalities. Mice lacking the encoded protein exhibit growth deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Oct 2015]

UniProt Comments for IGF-2

The insulin-like growth factors possess growth-promoting activity (Probable). Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development (Probable) (PubMed:2330056, PubMed:12087403). IGF-II is influenced by placental lactogen (Probable). Also involved in tissue differentiation (Probable). Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation (PubMed:16901893). In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver (Probable). Acts as a ligand for integrin which is required for IGF2 signaling ().

Research Articles on IGF-2

1. DIS3L2 loss of function results in transcriptional activation of the Igf2/H19 locus in nephron progenitor cells, most likely by leading to the activation of shared cis-regulatory elements that control these genes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with IGF-2 elisa kit

Products by Pathway	Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Endochondral Ossification Pathway antibodies	Endochondral Ossification Pathway Diagram
Hedgehog Signaling Pathway antibodies	Hedgehog Signaling Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
IGF1R Signaling Cascade Pathway antibodies	IGF1R Signaling Cascade Pathway Diagram
IRS-related Events Triggered By IGF1R Pathway antibodies	IRS-related Events Triggered By IGF1R Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
PI3K/Akt/mTOR Signaling Pathway antibodies	PI3K/Akt/mTOR Signaling Pathway Diagram
Platelet Activation, Signaling And Aggregation Pathway antibodies	Platelet Activation, Signaling And Aggregation Pathway Diagram
Platelet Degranulation Pathway antibodies	Platelet Degranulation Pathway Diagram

Diseases associated with IGF-2 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>629 publications with IGF-2 and Neoplasms
Wilms Tumor Antibodies	>141 publications with IGF-2 and Wilms Tumor
Beckwith-Wiedemann Syndrome Antibodies	>140 publications with IGF-2 and Beckwith-Wiedemann Syndrome
Growth Disorders Antibodies	>117 publications with IGF-2 and Growth Disorders
Kidney Diseases Antibodies	>113 publications with IGF-2 and Kidney Diseases
Colorectal Neoplasms Antibodies	>99 publications with IGF-2 and Colorectal Neoplasms
Liver Neoplasms Antibodies	>99 publications with IGF-2 and Liver Neoplasms
Liver Diseases Antibodies	>97 publications with IGF-2 and Liver Diseases
Carcinoma, Hepatocellular Antibodies	>62 publications with IGF-2 and Carcinoma, Hepatocellular
Breast Neoplasms Antibodies	>59 publications with IGF-2 and Breast Neoplasms

Organs/Tissues associated with IGF-2 elisa kit

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>254 publications with IGF-2 and Muscle
Liver Antibodies	>211 publications with IGF-2 and Liver
Embryonic Tissue Antibodies	>206 publications with IGF-2 and Embryonic Tissue
Kidney Antibodies	>140 publications with IGF-2 and Kidney
Bone Antibodies	>118 publications with IGF-2 and Bone
Brain Antibodies	>109 publications with IGF-2 and Brain
Heart Antibodies	>61 publications with IGF-2 and Heart
Lung Antibodies	>61 publications with IGF-2 and Lung
Pancreas Antibodies	>34 publications with IGF-2 and Pancreas
Ovary Antibodies	>33 publications with IGF-2 and Ovary