Oncostatin-M, OSM (OSM) ELISA Kit for Mouse

Name: Mouse OSM ELISA Kit; Oncostatin-M, OSM; MyBioSource
Brand: MyBioSource
SKU: MBS162523
Price: 445 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS162523

Intended Uses: This sandwich kit is for the accurate quantitative detection of Mouse Oncostatin-M (also known as OSM) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.Principles of the Assay: This kit is an Enzyme-Linked… More details

$445 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Oncostatin-M, OSM, ELISA Kit

Full Product Name

Mouse Oncostatin-M, OSM ELISA Kit

Product Gene Name

OSM elisa kit

Species Reactivity

Mouse

Assay Type

Quantitative Sandwich

Samples

Serum, plasma, cell culture supernates, cell lysates, tissue homogenates

Detection Range

10ng/L - 3000ng/L

Sensitivity

5.47ng/L

Preparation and Storage

Store at 2 to 8 degree C for 6 months.

Molecular Weight

28,484 Da

3D Structure

ModBase 3D Structure for P13725

Intra-Assay

CV<8%

Inter-Assay

CV<10%

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of OSM elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OSM purchase

MBS162523 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Oncostatin-M, OSM, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing OSM. The ELISA analytical biochemical technique of the MBS162523 kit is based on OSM antibody-OSM antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect OSM antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, OSM. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for OSM. It may not necessarily be applicable to this product.

NCBI GI #

10092621

NCBI GeneID

5008

NCBI Accession #

NP_065391.1

UniProt Primary Accession #

P13725

UniProt Secondary Accession #

Q6FHP8; Q9UCP6

UniProt Related Accession #

P13725

GenBank Nucleotide #

NM_020530.5

NCBI Official Full Name

oncostatin-M isoform 1 preproprotein

NCBI Official Synonym Full Names

oncostatin M

NCBI Official Symbol

OSM

UniProt Protein Name

Oncostatin-M

Protein Family

Oncostatin

UniProt Gene Name

OSM

UniProt Synonym Gene Names

OSM

NCBI Protein Information

oncostatin-M

NCBI Summary for OSM

This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]

UniProt Comments for OSM

Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration ().

Research Articles on OSM

1. The mechanism of prostaglandin E2-induced transcriptional up-regulation of Oncostatin-M by CREB and Sp1 has been described.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with OSM elisa kit

Reference Product	PubMed Publications
LIFR elisa kit	>384 publications with OSM and LIFR
STAT3 elisa kit	>221 publications with OSM and STAT3
IL6ST elisa kit	>176 publications with OSM and IL6ST
STAT1 elisa kit	>74 publications with OSM and STAT1
OSMR elisa kit	>60 publications with OSM and OSMR
SOCS3 elisa kit	>27 publications with OSM and SOCS3
VEGFA elisa kit	>6 publications with OSM and VEGFA
IL3 elisa kit	>2 publications with OSM and IL3

Pathways associated with OSM elisa kit

Products by Pathway	Pathway Diagram
Adipogenesis Pathway antibodies	Adipogenesis Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram
Oncostatin M Signaling Pathway antibodies	Oncostatin M Signaling Pathway Diagram
PI3K-Akt Signaling Pathway antibodies	PI3K-Akt Signaling Pathway Diagram
PI3K-Akt Signaling Pathway antibodies	PI3K-Akt Signaling Pathway Diagram

Diseases associated with OSM elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>323 publications with OSM and Neoplasms
Inflammation Antibodies	>189 publications with OSM and Inflammation
Necrosis Antibodies	>147 publications with OSM and Necrosis
Disease Models, Animal Antibodies	>64 publications with OSM and Disease Models, Animal
Liver Diseases Antibodies	>62 publications with OSM and Liver Diseases
Brain Diseases Antibodies	>61 publications with OSM and Brain Diseases
Kidney Diseases Antibodies	>50 publications with OSM and Kidney Diseases
Breast Neoplasms Antibodies	>39 publications with OSM and Breast Neoplasms
Lung Diseases Antibodies	>35 publications with OSM and Lung Diseases
Carcinoma, Hepatocellular Antibodies	>35 publications with OSM and Carcinoma, Hepatocellular

Organs/Tissues associated with OSM elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>434 publications with OSM and Blood
Kidney Antibodies	>124 publications with OSM and Kidney
Lung Antibodies	>92 publications with OSM and Lung
Intestine Antibodies	>20 publications with OSM and Intestine
Thymus Antibodies	>17 publications with OSM and Thymus
Ovary Antibodies	>14 publications with OSM and Ovary
Uncharacterized Tissue Antibodies	>2 publications with OSM and Uncharacterized Tissue