Ephrin Type A Receptor 1 (EPHA1) ELISA Kit for Human

Name: Human EPHA1 ELISA Kit; Ephrin Type A Receptor 1; MyBioSource
Brand: MyBioSource
SKU: MBS164613
Price: 425 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS164613

MBS164613 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Ephrin Type A Receptor 1 (EPHA1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$425 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Ephrin Type A Receptor 1 (EPHA1), ELISA Kit

Full Product Name

Human Ephrin Type A Receptor 1 (EPHA1) ELISA Kit

Product Gene Name

EPHA1 elisa kit

Species Reactivity

Human

Preparation and Storage

Store at 2 to 8 degree C for 6 months.

Molecular Weight

52,618 Da

3D Structure

ModBase 3D Structure for P21709

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of EPHA1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EPHA1. It may not necessarily be applicable to this product.

NCBI GI #

221316650

NCBI GeneID

2041

NCBI Accession #

NP_005223.4

UniProt Primary Accession #

P21709

UniProt Secondary Accession #

Q15405; A1L3V3; B5A966; B5A967

UniProt Related Accession #

P21709

GenBank Nucleotide #

NM_005232.4

NCBI Official Full Name

ephrin type-A receptor 1

NCBI Official Synonym Full Names

EPH receptor A1

NCBI Official Symbol

EPHA1

NCBI Official Synonym Symbols

EPH; EPHT; EPHT1

UniProt Protein Name

Ephrin type-A receptor 1

UniProt Synonym Protein Names

EPH tyrosine kinase; EPH tyrosine kinase 1; Erythropoietin-producing hepatoma receptor; Tyrosine-protein kinase receptor EPH

Protein Family

Ephrin type-A receptor

UniProt Gene Name

EPHA1

UniProt Synonym Gene Names

EPH; EPHT; EPHT1; hEpha1

NCBI Protein Information

ephrin type-A receptor 1

NCBI Summary for EPHA1

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis. [provided by RefSeq, Jul 2008]

UniProt Comments for EPHA1

Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis.

Research Articles on EPHA1

1. EphA1 expression is decreased in ovarian serous carcinoma compared with normal fallopian tube and benign ovarian serous cystadenoma. Decreased EphA1 expression was more often detected in high-grade tumors.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with EPHA1 elisa kit

Reference Product	PubMed Publications
EFNA1 elisa kit	>3 publications with EPHA1 and EFNA1

Pathways associated with EPHA1 elisa kit

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
EPHA Forward Signaling Pathway antibodies	EPHA Forward Signaling Pathway Diagram

Diseases associated with EPHA1 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>33 publications with EPHA1 and Neoplasms
Alzheimer Disease Antibodies	>14 publications with EPHA1 and Alzheimer Disease
Neurodegenerative Diseases Antibodies	>13 publications with EPHA1 and Neurodegenerative Diseases
Colorectal Neoplasms Antibodies	>6 publications with EPHA1 and Colorectal Neoplasms
Adenocarcinoma Antibodies	>6 publications with EPHA1 and Adenocarcinoma
Carcinoma, Squamous Cell Antibodies	>4 publications with EPHA1 and Carcinoma, Squamous Cell
Prostatic Neoplasms Antibodies	>4 publications with EPHA1 and Prostatic Neoplasms
Inflammation Antibodies	>4 publications with EPHA1 and Inflammation
Neoplasm Invasiveness Antibodies	>4 publications with EPHA1 and Neoplasm Invasiveness
Cell Transformation, Neoplastic Antibodies	>3 publications with EPHA1 and Cell Transformation, Neoplastic

Organs/Tissues associated with EPHA1 elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>29 publications with EPHA1 and Brain
Blood Antibodies	>19 publications with EPHA1 and Blood
Embryonic Tissue Antibodies	>11 publications with EPHA1 and Embryonic Tissue
Lung Antibodies	>8 publications with EPHA1 and Lung
Lymph Node Antibodies	>5 publications with EPHA1 and Lymph Node
Liver Antibodies	>5 publications with EPHA1 and Liver
Thymus Antibodies	>3 publications with EPHA1 and Thymus
Testis Antibodies	>2 publications with EPHA1 and Testis
Pancreas Antibodies	>2 publications with EPHA1 and Pancreas
Thyroid Antibodies	>1 publications with EPHA1 and Thyroid