Human NCAM-L1 ELISA Kit – Cat# MBS164860

Neural Cell Adhesion Molecule Ligand 1, NCAM-L1 (NCAM-L1) ELISA Kit for Human

Name: Human NCAM-L1 ELISA Kit; Neural Cell Adhesion Molecule Ligand 1, NCAM-L1; MyBioSource
Brand: MyBioSource
SKU: MBS164860
Price: 425 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS164860

Intended Uses: This sandwich kit is for the accurate quantitative detection of human Neural Cell Adhesion Molecule Ligand 1 (also known as NCAM-L1) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.Principles of the Assay: This kit… More details

$425 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Neural cell adhesion molecule ligand 1, NCAM-L1, ELISA Kit

Full Product Name

Human Neural cell adhesion molecule ligand 1, NCAM-L1 ELISA Kit

Product Gene Name

NCAM-L1 elisa kit

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Samples

Serum, plasma, cell culture supernates, cell lysates, tissue homogenates

Detection Range

0.1ng/ml - 30ng/ml

Sensitivity

0.046ng/ml

Preparation and Storage

Store at 2 to 8 degree C for 6 months.

Molecular Weight

139,517 Da

3D Structure

ModBase 3D Structure for P32004

Intra-Assay

CV<8%

Inter-Assay

CV<10%

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of NCAM-L1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NCAM-L1 purchase

MBS164860 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Neural cell adhesion molecule ligand 1, NCAM-L1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NCAM-L1. The ELISA analytical biochemical technique of the MBS164860 kit is based on NCAM-L1 antibody-NCAM-L1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NCAM-L1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NCAM-L1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for NCAM-L1. It may not necessarily be applicable to this product.

NCBI GI #

221316760

NCBI GeneID

3897

NCBI Accession #

NP_001137435.1

UniProt Primary Accession #

P32004

UniProt Secondary Accession #

Q8TA87; A0AV65; A4ZYW4; B2RMU7; G3XAF4

UniProt Related Accession #

P32004

GenBank Nucleotide #

NM_001143963.2

NCBI Official Full Name

neural cell adhesion molecule L1 isoform 3

NCBI Official Synonym Full Names

L1 cell adhesion molecule

NCBI Official Symbol

L1CAM

NCBI Official Synonym Symbols

S10; HSAS; MASA; MIC5; SPG1; CAML1; CD171; HSAS1; N-CAML1; NCAM-L1; N-CAM-L1

UniProt Protein Name

Neural cell adhesion molecule L1

UniProt Synonym Protein Names

CD_antigen: CD171

UniProt Gene Name

L1CAM

UniProt Synonym Gene Names

CAML1; MIC5; N-CAM-L1; NCAM-L1

NCBI Protein Information

neural cell adhesion molecule L1

NCBI Summary for NCAM-L1

The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013]

UniProt Comments for NCAM-L1

Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity.

Research Articles on NCAM-L1

1. L1CAM promotes esophageal squamous cell carcinoma tumorigenicity by upregulating ezrin expression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NCAM-L1 elisa kit

Reference Product	PubMed Publications
NCAM1 elisa kit	>1412 publications with NCAM-L1 and NCAM1
CNTN2 elisa kit	>16 publications with NCAM-L1 and CNTN2
NCAN elisa kit	>10 publications with NCAM-L1 and NCAN
ANK2 elisa kit	>6 publications with NCAM-L1 and ANK2
RANBP9 elisa kit	>1 publications with NCAM-L1 and RANBP9
CNTN1 elisa kit	>1 publications with NCAM-L1 and CNTN1
NUMB elisa kit	>1 publications with NCAM-L1 and NUMB

Pathways associated with NCAM-L1 elisa kit

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Basigin Interactions Pathway antibodies	Basigin Interactions Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Surface Interactions At The Vascular Wall Pathway antibodies	Cell Surface Interactions At The Vascular Wall Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Interaction Between L1 And Ankyrins Pathway antibodies	Interaction Between L1 And Ankyrins Pathway Diagram

Diseases associated with NCAM-L1 elisa kit

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>314 publications with NCAM-L1 and Nervous System Diseases
Neoplasms Antibodies	>235 publications with NCAM-L1 and Neoplasms
Brain Diseases Antibodies	>202 publications with NCAM-L1 and Brain Diseases
Disease Models, Animal Antibodies	>76 publications with NCAM-L1 and Disease Models, Animal
Adenocarcinoma Antibodies	>42 publications with NCAM-L1 and Adenocarcinoma
Drug Toxicity Antibodies	>38 publications with NCAM-L1 and Drug Toxicity
Ovarian Neoplasms Antibodies	>31 publications with NCAM-L1 and Ovarian Neoplasms
Cardiovascular Diseases Antibodies	>26 publications with NCAM-L1 and Cardiovascular Diseases
Aphasia Antibodies	>22 publications with NCAM-L1 and Aphasia
Hirschsprung Disease Antibodies	>21 publications with NCAM-L1 and Hirschsprung Disease

Organs/Tissues associated with NCAM-L1 elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>788 publications with NCAM-L1 and Brain
Nerve Antibodies	>437 publications with NCAM-L1 and Nerve
Embryonic Tissue Antibodies	>105 publications with NCAM-L1 and Embryonic Tissue
Ganglia Antibodies	>63 publications with NCAM-L1 and Ganglia
Eye Antibodies	>57 publications with NCAM-L1 and Eye
Muscle Antibodies	>46 publications with NCAM-L1 and Muscle
Kidney Antibodies	>36 publications with NCAM-L1 and Kidney
Skin Antibodies	>28 publications with NCAM-L1 and Skin
Lung Antibodies	>27 publications with NCAM-L1 and Lung
Liver Antibodies	>27 publications with NCAM-L1 and Liver