Endothelin 1, Et-1 (ET-1) ELISA Kit for Porcine

Name: Porcine ET-1 ELISA Kit; Endothelin 1, Et-1; MyBioSource
Brand: MyBioSource
SKU: MBS164948
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS164948

Intended Uses: This sandwich kit is for the accurate quantitative detection of Porcine Endothelin 1 (also known as ET-1) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.Principles of the Assay: This kit is an Enzyme-Linked… More details

$520 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

endothelin 1, ET-1, ELISA Kit

Full Product Name

Porcine endothelin 1, ET-1 ELISA Kit

Product Gene Name

ET-1 elisa kit

Species Reactivity

Porcine

Assay Type

Quantitative Sandwich

Samples

Serum, plasma, cell culture supernates, cell lysates, tissue homogenates

Detection Range

3ng/ml - 700ng/ml

Sensitivity

1.52ng/ml

Preparation and Storage

Store at 2 to 8 degree C for 6 months.

Molecular Weight

24,425 Da

3D Structure

ModBase 3D Structure for P05305

Intra-Assay

CV<8%

Inter-Assay

CV<10%

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ET-1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ET-1 purchase

MBS164948 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the endothelin 1, ET-1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ET-1. The ELISA analytical biochemical technique of the MBS164948 kit is based on ET-1 antibody-ET-1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ET-1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ET-1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for ET-1. It may not necessarily be applicable to this product.

NCBI GI #

556203

NCBI GeneID

1906

NCBI Accession #

AAA52339.1

UniProt Primary Accession #

P05305

UniProt Secondary Accession #

Q96DA1

UniProt Related Accession #

P05305

NCBI Official Full Name

endothelin-1

NCBI Official Synonym Full Names

endothelin 1

NCBI Official Symbol

EDN1

NCBI Official Synonym Symbols

ET1; QME; PPET1; ARCND3; HDLCQ7

UniProt Protein Name

Endothelin-1

UniProt Synonym Protein Names

Preproendothelin-1; PPET1

Protein Family

Endothelin

UniProt Gene Name

EDN1

UniProt Synonym Gene Names

PPET1; ET-1

NCBI Protein Information

endothelin-1

NCBI Summary for ET-1

This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

UniProt Comments for ET-1

Endothelins are endothelium-derived vasoconstrictor peptides.

Research Articles on ET-1

1. Endothelin-1 is a regulator of Mena expression in the serous ovarian cancer.Endothelin-1 role in the invadopodian function.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ET-1 elisa kit

Reference Product	PubMed Publications
EDNRA elisa kit	>35 publications with ET-1 and EDNRA
EDNRB elisa kit	>25 publications with ET-1 and EDNRB
JUN elisa kit	>19 publications with ET-1 and JUN
ECE1 elisa kit	>14 publications with ET-1 and ECE1
FOS elisa kit	>2 publications with ET-1 and FOS
HIF1A elisa kit	>1 publications with ET-1 and HIF1A
GATA2 elisa kit	>1 publications with ET-1 and GATA2
AKT1 elisa kit	>1 publications with ET-1 and AKT1

Pathways associated with ET-1 elisa kit

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
EGFR-dependent Endothelin Signaling Events Pathway antibodies	EGFR-dependent Endothelin Signaling Events Pathway Diagram
Endothelin Pathway antibodies	Endothelin Pathway Diagram
Endothelins Pathway antibodies	Endothelins Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies	Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
HIF-1 Signaling Pathway antibodies	HIF-1 Signaling Pathway Diagram
HIF-1-alpha Transcription Factor Network Pathway antibodies	HIF-1-alpha Transcription Factor Network Pathway Diagram

Diseases associated with ET-1 elisa kit

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>31 publications with ET-1 and Cardiovascular Diseases
Hypertension Antibodies	>26 publications with ET-1 and Hypertension
Craniofacial Abnormalities Antibodies	>16 publications with ET-1 and Craniofacial Abnormalities
Inflammation Antibodies	>15 publications with ET-1 and Inflammation
Asthma Antibodies	>13 publications with ET-1 and Asthma
Cardiovascular Abnormalities Antibodies	>6 publications with ET-1 and Cardiovascular Abnormalities
Kidney Diseases Antibodies	>6 publications with ET-1 and Kidney Diseases
Necrosis Antibodies	>5 publications with ET-1 and Necrosis
Heart Defects, Congenital Antibodies	>5 publications with ET-1 and Heart Defects, Congenital
Heart Failure Antibodies	>4 publications with ET-1 and Heart Failure

Organs/Tissues associated with ET-1 elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>12 publications with ET-1 and Brain
Liver Antibodies	>3 publications with ET-1 and Liver