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Toll-Like Receptor 10, TLR10 (TLR10) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS165150

Principle of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with Human TLR10 antibody. TLR10 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human TLR10… More details

$425 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Toll-like receptor 10, TLR10, ELISA Kit
Full Product Name
Human Toll-like receptor 10, TLR10 ELISA Kit
Product Gene Name
TLR10 elisa kit
Species Reactivity
Human
Assay Type
Quantitative Sandwich
Samples
Serum, plasma, cell culture supernates, Ascites, tissue homogenates or other biological fluids
Detection Range
1-400ng/mL
Sensitivity
0.53ng/mL
Preparation and Storage
Store at 2 to 8 degree C for 6 months.
Inter-assay Precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision. CV(%) = SD/mean x 100. Inter-Assay: CV<10%
Intra-assay Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision. Intra-Assay: CV<8%
Molecular Weight
94,564 Da
3D Structure
ModBase 3D Structure for Q9BXR5
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Typical Testing Data/Standard Curve (for reference only) of TLR10 elisa kit

Human TLR10 ELISA Kit – Cat# MBS165150

Other Notes

Small volumes of TLR10 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TLR10 purchase

MBS165150 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Toll-like receptor 10, TLR10, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TLR10. The ELISA analytical biochemical technique of the MBS165150 kit is based on TLR10 antibody-TLR10 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TLR10 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TLR10. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for TLR10. It may not necessarily be applicable to this product.

NCBI GI #
67626203
NCBI GeneID
81793
NCBI Accession #
AAY78491.1
UniProt Primary Accession #
Q9BXR5
UniProt Secondary Accession #
Q32MI7; Q32MI8; Q5FWG4; Q6UXL3; A8K7L1; B3Y668; D1CS21; D1CS22
UniProt Related Accession #
Q9BXR5
NCBI Official Full Name
TLR10
NCBI Official Synonym Full Names
toll like receptor 10
NCBI Official Symbol
TLR10
NCBI Official Synonym Symbols
CD290
UniProt Protein Name
Toll-like receptor 10
UniProt Synonym Protein Names
CD_antigen: CD290
Protein Family
Toll-like receptor
UniProt Gene Name
TLR10
NCBI Protein Information
toll-like receptor 10

NCBI Summary for TLR10

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2010]
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UniProt Comments for TLR10

Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response ().

Research Articles on TLR10

1. rs4129009 polymorphism increased the risk of persistent asthma continuing from five to seven years of age until 11-13 years of age and increased the risk of needing inhaled corticosteroids at 11-13 years of age

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TLR10 elisa kit

 Reference Product  PubMed Publications
 TLR1 elisa kit  >80 publications with TLR10 and TLR1
 TLR2 elisa kit  >64 publications with TLR10 and TLR2
 MYD88 elisa kit  >9 publications with TLR10 and MYD88
 FOXP3 elisa kit  >2 publications with TLR10 and FOXP3

Pathways associated with TLR10 elisa kit

 Products by Pathway  Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 MyD88 Cascade Initiated On Plasma Membrane Pathway antibodies  MyD88 Cascade Initiated On Plasma Membrane Pathway Diagram
 Toll Like Receptor 10 (TLR10) Cascade Pathway antibodies  Toll Like Receptor 10 (TLR10) Cascade Pathway Diagram
 Toll Like Receptor 5 (TLR5) Cascade Pathway antibodies  Toll Like Receptor 5 (TLR5) Cascade Pathway Diagram
 Toll-Like Receptors Cascades Pathway antibodies  Toll-Like Receptors Cascades Pathway Diagram

Diseases associated with TLR10 elisa kit

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >29 publications with TLR10 and Inflammation
 Neoplasms Antibodies  >19 publications with TLR10 and Neoplasms
 Necrosis Antibodies  >6 publications with TLR10 and Necrosis
 Prostatic Neoplasms Antibodies  >3 publications with TLR10 and Prostatic Neoplasms
 Kidney Diseases Antibodies  >3 publications with TLR10 and Kidney Diseases
 Eye Diseases Antibodies  >2 publications with TLR10 and Eye Diseases
 Breast Neoplasms Antibodies  >1 publications with TLR10 and Breast Neoplasms
 Heart Diseases Antibodies  >1 publications with TLR10 and Heart Diseases
 Proteinuria Antibodies  >1 publications with TLR10 and Proteinuria
 Hyperplasia Antibodies  >1 publications with TLR10 and Hyperplasia

Organs/Tissues associated with TLR10 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >7 publications with TLR10 and Lung
 Lymph Node Antibodies  >5 publications with TLR10 and Lymph Node
 Pharynx Antibodies  >3 publications with TLR10 and Pharynx
 Intestine Antibodies  >2 publications with TLR10 and Intestine
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