Wingless-Type Mmtv Integration Site Family, Member 9b (WNT9B) ELISA Kit for Hamster

The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region. [provided by RefSeq, Jul 2008]

WNT9B: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Belongs to the Wnt family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: proteinaceous extracellular matrix; extracellular space; extracellular region

Molecular Function: frizzled binding

Biological Process: positive regulation of catalytic activity; regulation of protein amino acid phosphorylation; cell fate commitment; Wnt receptor signaling pathway; response to retinoic acid; regulation of asymmetric cell division; in utero embryonic development; Wnt receptor signaling pathway, planar cell polarity pathway; multicellular organismal development; embryonic cranial skeleton morphogenesis; palate development; Wnt receptor signaling pathway through beta-catenin; cellular response to starvation; neuron differentiation; cell-cell signaling; ureteric bud branching; male genitalia development; regulation of tube size