Corticotropin Releasing Hormone, CRH (CRH) ELISA Kit for Porcine

Name: Porcine CRH ELISA Kit; Corticotropin Releasing Hormone, CRH; MyBioSource
Brand: MyBioSource
SKU: MBS165297
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS165297

Intended Uses: This sandwich kit is for the accurate quantitative detection of Porcine Corticotropin Releasing Hormone (also known as CRH) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.Principles of the Assay: This kit is an… More details

$520 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

corticotropin releasing hormone, CRH, ELISA Kit

Full Product Name

Porcine corticotropin releasing hormone, CRH ELISA Kit

Product Gene Name

CRH elisa kit

Species Reactivity

Porcine

Assay Type

Quantitative Sandwich

Samples

Serum, plasma, cell culture supernates, cell lysates, tissue homogenates

Detection Range

5ng/L - 1500ng/L

Sensitivity

2.62ng/L

Preparation and Storage

Store at 2 to 8 degree C for 6 months.

Molecular Weight

21,422 Da

3D Structure

ModBase 3D Structure for P06850

Intra-Assay

CV<8%

Inter-Assay

CV<10%

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CRH elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CRH purchase

MBS165297 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the corticotropin releasing hormone, CRH, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CRH. The ELISA analytical biochemical technique of the MBS165297 kit is based on CRH antibody-CRH antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CRH antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CRH. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for CRH. It may not necessarily be applicable to this product.

NCBI GI #

119607303

NCBI GeneID

1392

NCBI Accession #

EAW86897.1

UniProt Primary Accession #

P06850

UniProt Secondary Accession #

B3KQS4

UniProt Related Accession #

P06850

NCBI Official Full Name

corticotropin releasing hormone

NCBI Official Synonym Full Names

corticotropin releasing hormone

NCBI Official Symbol

CRH

NCBI Official Synonym Symbols

CRF; CRH1

UniProt Protein Name

Corticoliberin

UniProt Synonym Protein Names

Corticotropin-releasing factor; CRF; Corticotropin-releasing hormone

Protein Family

Corticoliberin

UniProt Gene Name

CRH

UniProt Synonym Gene Names

CRF

NCBI Protein Information

corticoliberin

NCBI Summary for CRH

This gene encodes a member of the corticotropin-releasing factor family. The encoded preproprotein is proteolytically processed to generate the mature neuropeptide hormone. In response to stress, this hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus, binds to corticotropin releasing hormone receptors and stimulates the release of adrenocorticotropic hormone from the pituitary gland. Marked reduction in this protein has been observed in association with Alzheimer's disease. Autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes, and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Nov 2015]

UniProt Comments for CRH

Hormone regulating the release of corticotropin from pituitary gland (). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile ().

Research Articles on CRH

1. These results show epigenetic changes in the CRH gene related to severity of suicide attempt in adults and a general psychiatric risk score in adolescents.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CRH elisa kit

Reference Product	PubMed Publications
POMC elisa kit	>2134 publications with CRH and POMC
AVP elisa kit	>513 publications with CRH and AVP
NPY elisa kit	>165 publications with CRH and NPY
GHRH elisa kit	>149 publications with CRH and GHRH
CRHR1 elisa kit	>142 publications with CRH and CRHR1
UCN elisa kit	>81 publications with CRH and UCN
CRHR2 elisa kit	>63 publications with CRH and CRHR2
ADCYAP1 elisa kit	>13 publications with CRH and ADCYAP1
MC4R elisa kit	>11 publications with CRH and MC4R

Pathways associated with CRH elisa kit

Products by Pathway	Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Alcoholism Pathway antibodies	Alcoholism Pathway Diagram
Class B/2 (Secretin Family Receptors) Pathway antibodies	Class B/2 (Secretin Family Receptors) Pathway Diagram
G Alpha (s) Signalling Events Pathway antibodies	G Alpha (s) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Long-term Depression Pathway antibodies	Long-term Depression Pathway Diagram
Long-term Depression Pathway antibodies	Long-term Depression Pathway Diagram
Myometrial Relaxation And Contraction Pathways antibodies	Myometrial Relaxation And Contraction Pathways Diagram
Rapid Glucocorticoid Signaling Pathway antibodies	Rapid Glucocorticoid Signaling Pathway Diagram

Diseases associated with CRH elisa kit

Disease Name	Pubmed Publications
Mental Disorders Antibodies	>624 publications with CRH and Mental Disorders
Nervous System Diseases Antibodies	>612 publications with CRH and Nervous System Diseases
Brain Diseases Antibodies	>483 publications with CRH and Brain Diseases
Cushing Syndrome Antibodies	>361 publications with CRH and Cushing Syndrome
Depressive Disorder Antibodies	>304 publications with CRH and Depressive Disorder
Inflammation Antibodies	>228 publications with CRH and Inflammation
Anxiety Disorders Antibodies	>213 publications with CRH and Anxiety Disorders
Necrosis Antibodies	>126 publications with CRH and Necrosis
Hypertension Antibodies	>112 publications with CRH and Hypertension
Pain Antibodies	>96 publications with CRH and Pain

Organs/Tissues associated with CRH elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>3058 publications with CRH and Brain
Adrenal Gland Antibodies	>764 publications with CRH and Adrenal Gland
Placenta Antibodies	>267 publications with CRH and Placenta
Muscle Antibodies	>139 publications with CRH and Muscle
Embryonic Tissue Antibodies	>118 publications with CRH and Embryonic Tissue
Uterus Antibodies	>113 publications with CRH and Uterus
Connective Tissue Antibodies	>42 publications with CRH and Connective Tissue
Pancreas Antibodies	>17 publications with CRH and Pancreas
Uncharacterized Tissue Antibodies	>1 publications with CRH and Uncharacterized Tissue