Sclerostin Domain-Containing Protein 1 (SOSTDC1) ELISA Kit for Rat

Name: Rat SOSTDC1 ELISA Kit; Sclerostin Domain-Containing Protein 1; MyBioSource
Brand: MyBioSource
SKU: MBS7252576
Price: 580 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7252576

MBS7252576 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Sclerostin domain-containing protein 1 (SOSTDC1) ELISA Kit target analytes in biological samples. The concentration gradients… More details

$580 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Sclerostin domain-containing protein 1 (SOSTDC1), ELISA Kit

Full Product Name

Rat Sclerostin domain-containing protein 1 (SOSTDC1) ELISA Kit

Product Gene Name

SOSTDC1 elisa kit

Species Reactivity

Rat

Assay Type

Competitive

Samples

Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate

Detection Range

1.0-25ng/mL

Sensitivity

0.1ng/ml

Preparation and Storage

Store all reagents at 2-8 degree C.

Molecular Weight

26,260 Da

OMIM

609675

Sample Preparation

We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team

Product Categories/Family for SOSTDC1 elisa kit

Signal Transduction

ISO Certification

Manufactured in an ISO 13485:2016 Certified Laboratory.

Other Notes

Small volumes of SOSTDC1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SOSTDC1. It may not necessarily be applicable to this product.

NCBI GI #

23943785

NCBI GeneID

25928

NCBI Accession #

NP_056279.1

UniProt Secondary Accession #

Q96HJ7; Q9Y3U3; A8MUA6

UniProt Related Accession #

Q6X4U4

GenBank Nucleotide #

NM_015464.2

NCBI Official Full Name

sclerostin domain-containing protein 1

NCBI Official Synonym Full Names

sclerostin domain containing 1

NCBI Official Symbol

SOSTDC1

NCBI Official Synonym Symbols

USAG1; CDA019; ECTODIN

UniProt Protein Name

Sclerostin domain-containing protein 1

UniProt Synonym Protein Names

Ectodermal BMP inhibitor; Ectodin; Uterine sensitization-associated gene 1 protein; USAG-1

Protein Family

Sclerostin domain-containing protein

UniProt Gene Name

SOSTDC1

UniProt Synonym Gene Names

USAG1; CDA019; Ectodin; USAG-1

UniProt Entry Name

SOSD1_HUMAN

NCBI Protein Information

sclerostin domain-containing protein 1; ectodermal BMP inhibitor; cystine-knot containing secreted protein; uterine sensitization-associated protein-1

NCBI Summary for SOSTDC1

This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death. [provided by RefSeq, Jul 2008]

UniProt Comments for SOSTDC1

SOSTDC1: May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling. Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. Belongs to the sclerostin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 7p21.1

Cellular Component: extracellular space

Biological Process: hair follicle morphogenesis; Wnt receptor signaling pathway; pattern specification process; odontogenesis of dentine-containing teeth; negative regulation of BMP signaling pathway; negative regulation of cell fate commitment

Research Articles on SOSTDC1

1. Unliganded VDR upregulates the expression of hairless, the gene product of which acts as a downstream comodulator to feedback-repress DKKL1 and SOSTDC1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SOSTDC1 elisa kit

Reference Product	PubMed Publications
BMP4 elisa kit	>6 publications with SOSTDC1 and BMP4
BMP7 elisa kit	>4 publications with SOSTDC1 and BMP7
BMP2 elisa kit	>2 publications with SOSTDC1 and BMP2

Pathways associated with SOSTDC1 elisa kit

Products by Pathway	Pathway Diagram
BMP Receptor Signaling Pathway antibodies	BMP Receptor Signaling Pathway Diagram

Diseases associated with SOSTDC1 elisa kit

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>11 publications with SOSTDC1 and Kidney Diseases
Congenital Abnormalities Antibodies	>9 publications with SOSTDC1 and Congenital Abnormalities
Disease Models, Animal Antibodies	>5 publications with SOSTDC1 and Disease Models, Animal
Adenocarcinoma Antibodies	>2 publications with SOSTDC1 and Adenocarcinoma
Craniofacial Abnormalities Antibodies	>2 publications with SOSTDC1 and Craniofacial Abnormalities
Abnormalities, Multiple Antibodies	>2 publications with SOSTDC1 and Abnormalities, Multiple
Necrosis Antibodies	>1 publications with SOSTDC1 and Necrosis
Inflammation Antibodies	>1 publications with SOSTDC1 and Inflammation
Liver Diseases Antibodies	>1 publications with SOSTDC1 and Liver Diseases
Hypospadias Antibodies	>1 publications with SOSTDC1 and Hypospadias

Organs/Tissues associated with SOSTDC1 elisa kit

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>20 publications with SOSTDC1 and Embryonic Tissue
Mouth Antibodies	>13 publications with SOSTDC1 and Mouth
Kidney Antibodies	>13 publications with SOSTDC1 and Kidney
Skin Antibodies	>9 publications with SOSTDC1 and Skin
Connective Tissue Antibodies	>5 publications with SOSTDC1 and Connective Tissue
Brain Antibodies	>4 publications with SOSTDC1 and Brain
Uterus Antibodies	>3 publications with SOSTDC1 and Uterus
Stomach Antibodies	>1 publications with SOSTDC1 and Stomach
Lung Antibodies	>1 publications with SOSTDC1 and Lung
Placenta Antibodies	>1 publications with SOSTDC1 and Placenta