Hyaluronan Synthase 3, HAS3 (HAS3) ELISA Kit for Human

Name: Human HAS3 ELISA Kit; Hyaluronan Synthase 3, HAS3; MyBioSource
Brand: MyBioSource
SKU: MBS165852
Price: 425 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS165852

Principle of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with Human HAS3 antibody. HAS3 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human HAS3… More details

$425 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Hyaluronan synthase 3, HAS3, ELISA Kit

Full Product Name

Human Hyaluronan synthase 3, HAS3 ELISA Kit

Product Gene Name

HAS3 elisa kit

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Samples

Serum, plasma, cell culture supernates, Ascites, tissue homogenates or other biological fluids

Detection Range

20-6000ng/L

Sensitivity

9.87ng/L

Preparation and Storage

Store at 2 to 8 degree C for 6 months.

Inter-assay Precision

Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision. CV(%) = SD/mean x 100. Inter-Assay: CV<10%

Intra-assay Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision. Intra-Assay: CV<8%

Molecular Weight

31,200 Da

3D Structure

ModBase 3D Structure for O00219

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of HAS3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HAS3 purchase

MBS165852 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Hyaluronan synthase 3, HAS3, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HAS3. The ELISA analytical biochemical technique of the MBS165852 kit is based on HAS3 antibody-HAS3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HAS3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HAS3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for HAS3. It may not necessarily be applicable to this product.

NCBI GI #

1932811

NCBI GeneID

3038

NCBI Accession #

AAC51209.1

UniProt Primary Accession #

O00219

UniProt Secondary Accession #

Q8WTZ0; Q9NYP0; A8K5T5

UniProt Related Accession #

O00219

NCBI Official Full Name

hyaluronan synthase 3, partial

NCBI Official Synonym Full Names

hyaluronan synthase 3

NCBI Official Symbol

HAS3

UniProt Protein Name

Hyaluronan synthase 3

UniProt Synonym Protein Names

Hyaluronate synthase 3; Hyaluronic acid synthase 3; HA synthase 3

Protein Family

Hyaluronan synthase

UniProt Gene Name

HAS3

UniProt Synonym Gene Names

HA synthase 3

NCBI Protein Information

hyaluronan synthase 3

NCBI Summary for HAS3

The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

UniProt Comments for HAS3

Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction ().

Research Articles on HAS3

1. Hyaluronan synthase 3 (HAS3) and tumor necrosis factor-alpha (TNF-alpha) formed an inter-regulation loop to enhance tumorigenesis in oral cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HAS3 elisa kit

Reference Product	PubMed Publications
HAS2 elisa kit	>154 publications with HAS3 and HAS2
CD44 elisa kit	>52 publications with HAS3 and CD44
HYAL2 elisa kit	>20 publications with HAS3 and HYAL2

Pathways associated with HAS3 elisa kit

Products by Pathway	Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Glycosaminoglycan Metabolism Pathway antibodies	Glycosaminoglycan Metabolism Pathway Diagram
Hyaluronan Biosynthesis And Export Pathway antibodies	Hyaluronan Biosynthesis And Export Pathway Diagram
Hyaluronan Metabolism Pathway antibodies	Hyaluronan Metabolism Pathway Diagram
MPS I - Hurler Syndrome Pathway antibodies	MPS I - Hurler Syndrome Pathway Diagram
MPS II - Hunter Syndrome Pathway antibodies	MPS II - Hunter Syndrome Pathway Diagram
MPS IIIA - Sanfilippo Syndrome A Pathway antibodies	MPS IIIA - Sanfilippo Syndrome A Pathway Diagram
MPS IIIB - Sanfilippo Syndrome B Pathway antibodies	MPS IIIB - Sanfilippo Syndrome B Pathway Diagram
MPS IIIC - Sanfilippo Syndrome C Pathway antibodies	MPS IIIC - Sanfilippo Syndrome C Pathway Diagram
MPS IIID - Sanfilippo Syndrome D Pathway antibodies	MPS IIID - Sanfilippo Syndrome D Pathway Diagram

Diseases associated with HAS3 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>46 publications with HAS3 and Neoplasms
Inflammation Antibodies	>19 publications with HAS3 and Inflammation
Necrosis Antibodies	>17 publications with HAS3 and Necrosis
Skin Diseases Antibodies	>13 publications with HAS3 and Skin Diseases
Disease Models, Animal Antibodies	>12 publications with HAS3 and Disease Models, Animal
Neovascularization, Pathologic Antibodies	>8 publications with HAS3 and Neovascularization, Pathologic
Cardiovascular Diseases Antibodies	>7 publications with HAS3 and Cardiovascular Diseases
Hyperplasia Antibodies	>6 publications with HAS3 and Hyperplasia
Ovarian Neoplasms Antibodies	>6 publications with HAS3 and Ovarian Neoplasms
Breast Neoplasms Antibodies	>4 publications with HAS3 and Breast Neoplasms

Organs/Tissues associated with HAS3 elisa kit

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>12 publications with HAS3 and Kidney
Lung Antibodies	>11 publications with HAS3 and Lung
Connective Tissue Antibodies	>11 publications with HAS3 and Connective Tissue
Prostate Antibodies	>9 publications with HAS3 and Prostate
Eye Antibodies	>9 publications with HAS3 and Eye
Embryonic Tissue Antibodies	>7 publications with HAS3 and Embryonic Tissue
Mouth Antibodies	>4 publications with HAS3 and Mouth
Thyroid Antibodies	>3 publications with HAS3 and Thyroid
Intestine Antibodies	>3 publications with HAS3 and Intestine
Bladder Antibodies	>3 publications with HAS3 and Bladder