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Interferon Regulatory Factor 2, IRF2 (IRF2) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS166682

MBS166682 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the interferon regulatory factor 2, IRF2, ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$425 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
interferon regulatory factor 2, IRF2, ELISA Kit
Full Product Name
Human interferon regulatory factor 2, IRF2 ELISA Kit
Product Gene Name
IRF2 elisa kit
Species Reactivity
Human
Preparation and Storage
Store at 2 to 8 degree C for 6 months.
Molecular Weight
39,156 Da
3D Structure
ModBase 3D Structure for P14316
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of IRF2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IRF2. It may not necessarily be applicable to this product.

NCBI GI #
153082752
NCBI GeneID
3660
NCBI Accession #
NP_002190.2
UniProt Primary Accession #
P14316
UniProt Secondary Accession #
Q6IAS7; Q96B99; D6RCK5; H0Y8S3
UniProt Related Accession #
P14316
GenBank Nucleotide #
NM_002199.3
NCBI Official Full Name
interferon regulatory factor 2
NCBI Official Synonym Full Names
interferon regulatory factor 2
NCBI Official Symbol
IRF2
NCBI Official Synonym Symbols
IRF-2
UniProt Protein Name
Interferon regulatory factor 2
Protein Family
Interferon regulatory factor
UniProt Gene Name
IRF2
UniProt Synonym Gene Names
IRF-2
NCBI Protein Information
interferon regulatory factor 2

NCBI Summary for IRF2

IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4. [provided by RefSeq, Jul 2008]
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UniProt Comments for IRF2

Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.
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Research Articles on IRF2

1. These finding suggests that miR-302b inhibits key transcription factors and cytokines by targeting ERBB4, IRF2 and CXCR4, implicating its role in the inhibition of CRI in EC.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IRF2 elisa kit

 Reference Product  PubMed Publications
 STAT1 elisa kit  >30 publications with IRF2 and STAT1
 IRF8 elisa kit  >7 publications with IRF2 and IRF8
 EP300 elisa kit  >3 publications with IRF2 and EP300
 RELA elisa kit  >1 publications with IRF2 and RELA
 NFKB1 elisa kit  >1 publications with IRF2 and NFKB1

Pathways associated with IRF2 elisa kit

 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Interferon Signaling Pathway antibodies  Interferon Signaling Pathway Diagram
 Interferon Alpha/beta Signaling Pathway antibodies  Interferon Alpha/beta Signaling Pathway Diagram
 Interferon Gamma Signaling Pathway antibodies  Interferon Gamma Signaling Pathway Diagram
 RIG-I/MDA5 Mediated Induction Of IFN-alpha/beta Pathways antibodies  RIG-I/MDA5 Mediated Induction Of IFN-alpha/beta Pathways Diagram

Diseases associated with IRF2 elisa kit

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >13 publications with IRF2 and Necrosis
 Cell Transformation, Neoplastic Antibodies  >10 publications with IRF2 and Cell Transformation, Neoplastic
 Death Antibodies  >10 publications with IRF2 and Death
 Liver Diseases Antibodies  >10 publications with IRF2 and Liver Diseases
 Inflammation Antibodies  >10 publications with IRF2 and Inflammation
 Hepatitis Antibodies  >8 publications with IRF2 and Hepatitis
 Nervous System Diseases Antibodies  >8 publications with IRF2 and Nervous System Diseases
 Breast Neoplasms Antibodies  >5 publications with IRF2 and Breast Neoplasms
 Liver Neoplasms Antibodies  >4 publications with IRF2 and Liver Neoplasms
 Brain Diseases Antibodies  >4 publications with IRF2 and Brain Diseases

Organs/Tissues associated with IRF2 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >48 publications with IRF2 and Blood
 Bone Antibodies  >20 publications with IRF2 and Bone
 Bone Marrow Antibodies  >19 publications with IRF2 and Bone Marrow
 Liver Antibodies  >15 publications with IRF2 and Liver
 Skin Antibodies  >12 publications with IRF2 and Skin
 Lung Antibodies  >11 publications with IRF2 and Lung
 Brain Antibodies  >8 publications with IRF2 and Brain
 Uterus Antibodies  >7 publications with IRF2 and Uterus
 Spleen Antibodies  >7 publications with IRF2 and Spleen
 Heart Antibodies  >4 publications with IRF2 and Heart
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