Acid Ceramidase (ASAH1) ELISA Kit for Human

Name: Human ASAH1 ELISA Kit; Acid Ceramidase; MyBioSource
Brand: MyBioSource
SKU: MBS166822
Price: 425 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS166822

MBS166822 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Acid ceramidase (ASAH1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or… More details

$425 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Acid ceramidase (ASAH1), ELISA Kit

Full Product Name

Human Acid ceramidase (ASAH1) ELISA Kit

Product Gene Name

ASAH1 elisa kit

Species Reactivity

Human

Preparation and Storage

Store at 2 to 8 degree C for 6 months.

Molecular Weight

46,504 Da

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ASAH1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ASAH1. It may not necessarily be applicable to this product.

NCBI GI #

9651702

NCBI GeneID

427

NCBI Accession #

AAF91230.1

UniProt Secondary Accession #

Q6W898; Q96AS2; E9PDS0

UniProt Related Accession #

Q13510

NCBI Official Full Name

acid ceramidase

NCBI Official Synonym Full Names

N-acylsphingosine amidohydrolase 1

NCBI Official Symbol

ASAH1

NCBI Official Synonym Symbols

AC; PHP; ASAH; PHP32; ACDase; SMAPME

UniProt Protein Name

Acid ceramidase

UniProt Synonym Protein Names

Acylsphingosine deacylase; N-acylsphingosine amidohydrolase; Putative 32 kDa heart protein; PHP32

Protein Family

Acid ceramidase

UniProt Gene Name

ASAH1

UniProt Synonym Gene Names

ASAH; AC; ACDase; Acid CDase; PHP32

NCBI Protein Information

acid ceramidase

NCBI Summary for ASAH1

This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy. [provided by RefSeq, Oct 2015]

UniProt Comments for ASAH1

Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.

Research Articles on ASAH1

1. Acid ceramidase plays a critical role in acute myeloid leukemia cell survival via regulation of both sphingolipid levels and Mcl-1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ASAH1 elisa kit

Reference Product	PubMed Publications
ACER1 elisa kit	>9 publications with ASAH1 and ACER1
ACER2 elisa kit	>8 publications with ASAH1 and ACER2
SMPD1 elisa kit	>4 publications with ASAH1 and SMPD1
GBA elisa kit	>2 publications with ASAH1 and GBA
SPHK1 elisa kit	>2 publications with ASAH1 and SPHK1
GALC elisa kit	>2 publications with ASAH1 and GALC
UGCG elisa kit	>1 publications with ASAH1 and UGCG

Pathways associated with ASAH1 elisa kit

Products by Pathway	Pathway Diagram
Ceramide Signaling Pathway antibodies	Ceramide Signaling Pathway Diagram
Glycosphingolipid Metabolism Pathway antibodies	Glycosphingolipid Metabolism Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram
Lysosome Pathway antibodies	Lysosome Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Lipids And Lipoproteins Pathway antibodies	Metabolism Of Lipids And Lipoproteins Pathway Diagram
Neutrophil Degranulation Pathway antibodies	Neutrophil Degranulation Pathway Diagram

Diseases associated with ASAH1 elisa kit

Disease Name	Pubmed Publications
Farber Lipogranulomatosis Antibodies	>29 publications with ASAH1 and Farber Lipogranulomatosis
Lipidoses Antibodies	>27 publications with ASAH1 and Lipidoses
SPINAL MUSCULAR ATROPHY WITH PROGRESSIVE MYOCLONIC EPILEPSY Antibodies	>14 publications with ASAH1 and SPINAL MUSCULAR ATROPHY WITH PROGRESSIVE MYOCLONIC EPILEPSY
Seizures Antibodies	>10 publications with ASAH1 and Seizures
Liver Diseases Antibodies	>8 publications with ASAH1 and Liver Diseases
Cardiovascular Diseases Antibodies	>4 publications with ASAH1 and Cardiovascular Diseases
Inflammation Antibodies	>3 publications with ASAH1 and Inflammation
Necrosis Antibodies	>3 publications with ASAH1 and Necrosis
Fatty Liver Antibodies	>3 publications with ASAH1 and Fatty Liver
Heart Diseases Antibodies	>3 publications with ASAH1 and Heart Diseases

Organs/Tissues associated with ASAH1 elisa kit

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>23 publications with ASAH1 and Skin
Brain Antibodies	>21 publications with ASAH1 and Brain
Blood Antibodies	>19 publications with ASAH1 and Blood
Liver Antibodies	>14 publications with ASAH1 and Liver
Muscle Antibodies	>13 publications with ASAH1 and Muscle
Lung Antibodies	>10 publications with ASAH1 and Lung
Kidney Antibodies	>7 publications with ASAH1 and Kidney
Heart Antibodies	>6 publications with ASAH1 and Heart
Bone Antibodies	>5 publications with ASAH1 and Bone
Prostate Antibodies	>5 publications with ASAH1 and Prostate