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Monoglyceride Lipase (MGLL) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS167556

Intended Uses: This sandwich kit is for the accurate quantitative detection of human Monocyte Chemotactic Protein 4 (also known as MCP-4) in serum, plasma, cell culture supernates, cell lysates, tissue homogenates.Principle of the Assay: This kit is an… More details

$425 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Monoglyceride lipase (MGLL), ELISA Kit
Full Product Name
Human Monoglyceride lipase (MGLL) ELISA Kit
Product Gene Name
MGLL elisa kit
Species Reactivity
Human
Assay Type
Quantitative Sandwich
Samples
Serum, Plasma, Cell Culture Supernates, Cell Lysates, Tissue Homogenates
Detection Range
2ng/L-600ng/L
Sensitivity
1.57ng/L
Preparation and Storage
Store at 2 to 8 degree C for 6 months.
Inter-assay Precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision. CV(%) = SD/mean x 100. Inter-Assay: CV<10%
Intra-assay Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision. Intra-Assay: CV<8%
Molecular Weight
33,500 Da
3D Structure
ModBase 3D Structure for Q8R431
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Typical Testing Data/Standard Curve (for reference only) of MGLL elisa kit

Human MGLL ELISA Kit – Cat# MBS167556

Other Notes

Small volumes of MGLL elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MGLL purchase

MBS167556 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Monoglyceride lipase (MGLL) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MGLL. The ELISA analytical biochemical technique of the MBS167556 kit is based on MGLL antibody-MGLL antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MGLL antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MGLL. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for MGLL. It may not necessarily be applicable to this product.

NCBI GI #
19923092
NCBI GeneID
29254
NCBI Accession #
NP_612511.1
UniProt Primary Accession #
Q8R431
UniProt Secondary Accession #
Q32PZ2
UniProt Related Accession #
Q8R431
GenBank Nucleotide #
NM_138502.2
NCBI Official Full Name
monoglyceride lipase
NCBI Official Synonym Full Names
monoglyceride lipase
NCBI Official Symbol
Mgll
NCBI Official Synonym Symbols
MAGL
UniProt Protein Name
Monoglyceride lipase
UniProt Synonym Protein Names
Monoacylglycerol lipase; MAGL
Protein Family
Monoglyceride lipase
UniProt Gene Name
Mgll
UniProt Synonym Gene Names
MGL; MAGL
NCBI Protein Information
monoglyceride lipase

NCBI Summary for MGLL

serine hydrolase that converts monoglycerides to fatty acid and glycerol; may play a role in retrograde signaling at central synapses and other forms of short-range neuronal communication [RGD, Feb 2006]

UniProt Comments for MGLL

Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth.
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Research Articles on MGLL

1. 4 weeks of post-weaning social isolation increased aggressive grooming of a novel same-sex conspecific in male and female rats. Treatment with the MAGL inhibitor MJN110 eliminated this increase in aggressive grooming in both males and females, without reducing non-aggressive social behavior. Activation of the medial prefrontal cortex was increased by social interaction but was blunted by MJN110 only in females.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with MGLL elisa kit

 Products by Pathway  Pathway Diagram
 Acyl Chain Remodeling Of DAG And TAG Pathway antibodies  Acyl Chain Remodeling Of DAG And TAG Pathway Diagram
 Acylglycerol Degradation Pathway antibodies  Acylglycerol Degradation Pathway Diagram
 Acylglycerol Degradation Pathway antibodies  Acylglycerol Degradation Pathway Diagram
 Arachidonate Production From DAG Pathway antibodies  Arachidonate Production From DAG Pathway Diagram
 Effects Of PIP2 Hydrolysis Pathway antibodies  Effects Of PIP2 Hydrolysis Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram

Diseases associated with MGLL elisa kit

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >4 publications with MGLL and Inflammation
 Disease Models, Animal Antibodies  >3 publications with MGLL and Disease Models, Animal
 Fatty Liver Antibodies  >3 publications with MGLL and Fatty Liver
 Breast Neoplasms Antibodies  >2 publications with MGLL and Breast Neoplasms
 Liver Diseases Antibodies  >2 publications with MGLL and Liver Diseases
 Cardiovascular Diseases Antibodies  >1 publications with MGLL and Cardiovascular Diseases
 Weight Gain Antibodies  >1 publications with MGLL and Weight Gain
 Weight Loss Antibodies  >1 publications with MGLL and Weight Loss
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with MGLL and Prenatal Exposure Delayed Effects
 Necrosis Antibodies  >1 publications with MGLL and Necrosis

Organs/Tissues associated with MGLL elisa kit

 Organ/Tissue Name  Pubmed Publications
 Adipose Tissue Antibodies  >5 publications with MGLL and Adipose Tissue
 Liver Antibodies  >4 publications with MGLL and Liver
 Brain Antibodies  >2 publications with MGLL and Brain
 Connective Tissue Antibodies  >2 publications with MGLL and Connective Tissue
 Pancreas Antibodies  >1 publications with MGLL and Pancreas
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