Neuron Specific Enolase (ENO2) Protein

Name: ENO2 Protein; Neuron Specific Enolase; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS173164
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS173164

MyBioSource is the leading supplier of human brain Human Neuron Specific Antigen (NSE) for clinical research and manufacturing.Custom preparations, technical support, bulk quantities and aliquoting available.Associated Tumor Types: Small-Cell Carcinoma… More details

$520 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Neuron Specific Enolase (ENO2), Protein

Full Product Name

Neuron Specific Enolase (NSE), Human Brain

Product Gene Name

ENO2 protein

Product Synonym Gene Name

NSE

Product Synonym Names

2-Phospho-D-glycerate hydro-lyase; NSE; Enolase 2; Gamma-enolase; Neuron Specific Enolase (NSE), Human Brain - >=96% (SDS-PAGE)

Host

Human Brain

Form/Format

0.2 micron filtered, frozen solution in 0.01M sodium phosphate, 0.15 M sodium chloride and 0.005 M magnesium sulfate, pH 7.4

Purity/Purification

> 96% (SDS-PAGE)

Preparation and Storage

Store at -20°C. Ships on Dry Ice. Avoid freeze-thaws.

OMIM

131360

3D Structure

ModBase 3D Structure for P09104

CAS Number

9014-08-8

EC Number

4.2.1.11

Appearance

Clear, colorless, frozen liquid

Protein

2.2 mg/mL (E^0.1%_280nm=1.22)

Purity Note

Cluster of bands at 45,000 mw

Handling

Handle as a potentially hazardous substance.

Recovery

If small volume, microfuge vial before drawing from container.

Product Categories/Family for ENO2 protein

Proteins; Antigens; Enzymes; Standards/controls; Native Proteins; Immunogen; Neuron Specific Enolase (nse)

Other Notes

Small volumes of ENO2 protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ENO2 purchase

MBS173164 is a protein targeting ENO2. Also known as Neuron Specific Enolase (NSE), Human Brain. Host: Human Brain.

Additional Details

NCBI/Uniprot data below describe general gene information for ENO2. It may not necessarily be applicable to this product.

NCBI GI #

2465396

NCBI GeneID

24334

NCBI Accession #

AAB72088.1

UniProt Primary Accession #

P09104

UniProt Secondary Accession #

Q96J33; B7Z2X9

UniProt Related Accession #

P07323

NCBI Official Full Name

neuron-specific enolase

NCBI Official Synonym Full Names

enolase 2, gamma, neuronal

NCBI Official Symbol

Eno2

NCBI Official Synonym Symbols

NSE; RNEN3

UniProt Protein Name

Gamma-enolase

UniProt Synonym Protein Names

2-phospho-D-glycerate hydro-lyase; Enolase 2; Neural enolase; Neuron-specific enolase; NSE

Protein Family

Bifunctional enolase 2/transcriptional activator

UniProt Gene Name

ENO2

UniProt Synonym Gene Names

NSE

UniProt Entry Name

ENOG_HUMAN

NCBI Protein Information

gamma-enolase; neural enolase; neuron-specific enolase; 2-phospho-D-glycerate hydro-lyase

NCBI Summary for ENO2

catalyzes the interconversion of 2-phosphoglycerate to phosphoenolpyruvate; may play a role in glycolysis [RGD, Feb 2006]

UniProt Comments for ENO2

ENO2: an enzyme with 2-phospho-D-glycerate hydro-lyase activity. One of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates.

Protein type: Lyase; Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 4.2.1.11

Chromosomal Location of Human Ortholog: 12p13

Cellular Component: extracellular space; photoreceptor inner segment; phosphopyruvate hydratase complex; plasma membrane; perikaryon; cytosol

Molecular Function: magnesium ion binding; phosphopyruvate hydratase activity

Biological Process: glycolysis; carbohydrate metabolic process; glucose metabolic process; pathogenesis; gluconeogenesis

Research Articles on ENO2

1. Hyperglycemia may impair mitochondrial function and alter glycolysis in glomerular epithelial cells by down-regulating the expression of ATP synthase beta subunit and enolase 2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ENO2 protein

Reference Product	PubMed Publications
ALDOC protein	>3 publications with ENO2 and ALDOC
PCK1 protein	>3 publications with ENO2 and PCK1
GPI protein	>2 publications with ENO2 and GPI
PKM2 protein	>2 publications with ENO2 and PKM2
ALDOA protein	>1 publications with ENO2 and ALDOA
PKLR protein	>1 publications with ENO2 and PKLR

Pathways associated with ENO2 protein

Products by Pathway	Pathway Diagram
Biosynthesis Of Amino Acids Pathway antibodies	Biosynthesis Of Amino Acids Pathway Diagram
Biosynthesis Of Amino Acids Pathway antibodies	Biosynthesis Of Amino Acids Pathway Diagram
Carbon Metabolism Pathway antibodies	Carbon Metabolism Pathway Diagram
Carbon Metabolism Pathway antibodies	Carbon Metabolism Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Gluconeogenesis Pathway antibodies	Gluconeogenesis Pathway Diagram
Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway antibodies	Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway Diagram
Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway antibodies	Gluconeogenesis, Oxaloacetate => Fructose-6P Pathway Diagram
Glucose Metabolism Pathway antibodies	Glucose Metabolism Pathway Diagram
Glycogen Storage Diseases Pathway antibodies	Glycogen Storage Diseases Pathway Diagram

Diseases associated with ENO2 protein

Disease Name	Pubmed Publications
Disease Models, Animal Antibodies	>8 publications with ENO2 and Disease Models, Animal
Nervous System Diseases Antibodies	>7 publications with ENO2 and Nervous System Diseases
Brain Diseases Antibodies	>5 publications with ENO2 and Brain Diseases
Adenocarcinoma Antibodies	>4 publications with ENO2 and Adenocarcinoma
Kidney Diseases Antibodies	>3 publications with ENO2 and Kidney Diseases
Inflammation Antibodies	>2 publications with ENO2 and Inflammation
Prostatic Neoplasms Antibodies	>2 publications with ENO2 and Prostatic Neoplasms
Hypertension Antibodies	>2 publications with ENO2 and Hypertension
Lung Diseases Antibodies	>2 publications with ENO2 and Lung Diseases
Neoplasms, Experimental Antibodies	>2 publications with ENO2 and Neoplasms, Experimental

Organs/Tissues associated with ENO2 protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>17 publications with ENO2 and Brain
Blood Antibodies	>10 publications with ENO2 and Blood
Muscle Antibodies	>8 publications with ENO2 and Muscle
Skin Antibodies	>4 publications with ENO2 and Skin
Intestine Antibodies	>4 publications with ENO2 and Intestine
Vascular Antibodies	>4 publications with ENO2 and Vascular
Lung Antibodies	>4 publications with ENO2 and Lung
Kidney Antibodies	>4 publications with ENO2 and Kidney
Bone Antibodies	>4 publications with ENO2 and Bone
Testis Antibodies	>3 publications with ENO2 and Testis