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Prealbumin (LCN1) Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS173178

MyBioSource is the leading manufacturer of Standard Grade Human Plasma Prealbumin/Transthyretin.Custom preparations, technical support, bulk quantities and aliquoting available.Transthyretin (TTR) is a serum and cerebrospinal fluid carrier of the thyroid… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Prealbumin (LCN1), Protein
Full Product Name
Prealbumin/Transthyretin, Human Serum
Product Gene Name
Product Synonym Names
Transthyretin, Thyroxin Binding Prealbumin, TBPA
Form/Format
Lyophilized powder from 0.02M NH4HCO3. May contain traces of buffer salts.
Purity/Purification
>= 70% (SDS-PAGE)
Preparation and Storage
2-8 degree C
OMIM
151675
Source
Human Plasma
Reconstitution
Recommend using phosphate buffer, pH >7.0 with 0.15M NaCl
Advice
Reconstitute into provided container and centrifuge to ensure full recovery
Handling
Handle as a potentially hazardous substance.
Recertification
12-27-2017
CAS Number
87090-18-4

Other Notes

Small volumes of LCN1 protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LCN1 purchase

MBS173178 is a protein targeting LCN1. Also known as Prealbumin/Transthyretin, Human Serum.

Additional Details

NCBI/Uniprot data below describe general gene information for LCN1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
prealbumin
NCBI Official Synonym Full Names
lipocalin 1
NCBI Official Symbol
LCN1
NCBI Official Synonym Symbols
TP; TLC; PMFA; VEGP
UniProt Protein Name
Lipocalin-1
UniProt Synonym Protein Names
Tear lipocalin; Tlc; Tear prealbumin; TP; Von Ebner gland protein; VEG protein
Protein Family
UniProt Gene Name
LCN1
UniProt Synonym Gene Names
VEGP; Tlc; TP; VEG protein
UniProt Entry Name
LCN1_HUMAN
NCBI Protein Information
lipocalin-1; VEG protein; tear prealbumin; Von Ebner gland protein; lipocalin 1 (tear prealbumin); protein migrating faster than albumin

NCBI Summary for LCN1

This gene encodes a member of the lipocalin family of small secretory proteins. Lipocalins are extracellular transport proteins that bind to a variety of hydrophobic ligands. The encoded protein is the primary lipid binding protein in tears and is overproduced in response to multiple stimuli including infection and stress. The encoded protein may be a marker for chromosome aneuploidy as well as an autoantigen in Sjogren's syndrome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and two pseudogenes of this gene are also located on the long arm of chromosome 9. [provided by RefSeq, Nov 2011]
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UniProt Comments for LCN1

LCN1: Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket. Belongs to the calycin superfamily. Lipocalin family.

Protein type: Secreted; Secreted, signal peptide; Inhibitor

Chromosomal Location of Human Ortholog: 9q34

Cellular Component: extracellular space; extracellular region

Molecular Function: cysteine protease inhibitor activity

Biological Process: long-chain fatty acid transport; retinal homeostasis; sensory perception of taste; response to stimulus; proteolysis; transmembrane transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with LCN1 protein

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