Plasminogen (PLG) Active Protein

Name: PLG Active Protein; Plasminogen; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS173563
Price: 500 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS173563

MyBioSource is a leading supplier of Human Plasma PLASMINOGEN in research and bulk quantities.Custom preparations, technical support, bulk quantities and aliquoting available.Plasmin is released as a zymogen called PLASMINOGEN (PLG) from the liver into the… More details

$500 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Plasminogen (PLG), Active Protein

Full Product Name

Plasminogen (PLG), Human Plasma

Product Gene Name

PLG active protein

Product Synonym Names

PLG; Plasminogen (PLG) - >=95% (SDS-PAGE), Plasmin Precursor

Form/Format

Powder lyhophilized from 20mM tris, 2mM EDTA , pH7.5

Purity/Purification

>95% (SDS-PAGE)

Preparation and Storage

Store at -20°C. Protect from moisture.

Molecular Weight

88,400 (sequence)

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Source

Human Plasma

Unit Definition

Amount of enzyme which hydrolyzes one micromole of N-tosyl-L arginine-methyl ester in 30 minutes at 37 degree C, pH 8.0.

Protein

1.0 mg/vial (E^0.1%_280nm=1.71)

Activity

> 120 U/mg protein (after activation with streptokinase)

Handling

Handle as a potentially hazardous substance

Recovery

Centrifuge vial briefly to ensure full recovery

Product Categories/Family for PLG active protein

Proteins; Antigens; Enzymes; Standards/controls; Native Proteins; Plasminogen (plg)

Other Notes

Small volumes of PLG active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLG purchase

MBS173563 is an active protein targeting PLG. Also known as Plasminogen (PLG), Human Plasma.

Additional Details

NCBI/Uniprot data below describe general gene information for PLG. It may not necessarily be applicable to this product.

NCBI GI #

27806815

NCBI GeneID

280897

NCBI Accession #

NP_776376.1

UniProt Secondary Accession #

Q28162

UniProt Related Accession #

P06868

GenBank Nucleotide #

NM_173951.2

NCBI Official Full Name

plasminogen

NCBI Official Symbol

PLG

NCBI Official Synonym Symbols

LPA

UniProt Protein Name

Plasminogen

Protein Family

Plasminogen

UniProt Gene Name

PLG

UniProt Entry Name

PLMN_BOVIN

NCBI Protein Information

plasminogen; lipoprotein, Lp(a)

UniProt Comments for PLG

Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells ().

Research Articles on PLG

1. SUPA formed a higher avidity complex (118-fold) with bovine Pg than with human Pg and non-proteolytically activated bovine but not human Pg.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PLG active protein

Reference Product	PubMed Publications
SERPINE1 active protein	>43 publications with PLG and SERPINE1
PLAUR active protein	>14 publications with PLG and PLAUR
VWF active protein	>12 publications with PLG and VWF
A2M active protein	>2 publications with PLG and A2M

Pathways associated with PLG active protein

Products by Pathway	Pathway Diagram
Activation Of Matrix Metalloproteinases Pathway antibodies	Activation Of Matrix Metalloproteinases Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Degradation Of The Extracellular Matrix Pathway antibodies	Degradation Of The Extracellular Matrix Pathway Diagram
Dissolution Of Fibrin Clot Pathway antibodies	Dissolution Of Fibrin Clot Pathway Diagram
Extracellular Matrix Organization Pathway antibodies	Extracellular Matrix Organization Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Influenza A Pathway antibodies	Influenza A Pathway Diagram
Influenza A Pathway antibodies	Influenza A Pathway Diagram

Diseases associated with PLG active protein

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>111 publications with PLG and Cardiovascular Diseases
Nervous System Diseases Antibodies	>86 publications with PLG and Nervous System Diseases
Brain Diseases Antibodies	>57 publications with PLG and Brain Diseases
Inflammation Antibodies	>51 publications with PLG and Inflammation
Liver Diseases Antibodies	>38 publications with PLG and Liver Diseases
Blood Coagulation Disorders Antibodies	>33 publications with PLG and Blood Coagulation Disorders
Hemorrhage Antibodies	>24 publications with PLG and Hemorrhage
Necrosis Antibodies	>20 publications with PLG and Necrosis
Venous Thrombosis Antibodies	>20 publications with PLG and Venous Thrombosis
Heart Diseases Antibodies	>18 publications with PLG and Heart Diseases

Organs/Tissues associated with PLG active protein

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>78 publications with PLG and Liver
Embryonic Tissue Antibodies	>21 publications with PLG and Embryonic Tissue
Whole Body Antibodies	>9 publications with PLG and Whole Body