Rabbit Anti-INPP4B Monoclonal Antibody – Cat# MBS1750078

Western blot analysis of INPP4B expression in MCF-7 cell lysate (MBS1750078).

INPP4B Antibody – Rabbit Monoclonal

Name: INPP4B Antibody; Monoclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS1750078
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1750078

Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4- trisphosphate and inositol 1,4-bisphosphate. More details

$210 / 0.03 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

INPP4B/Type Ii 4 Phosphatase, Monoclonal Antibody

Full Product Name

Anti-INPP4B/Type Ii 4 Phosphatase Rabbit Monoclonal Antibody

Product Gene Name

anti-INPP4B antibody

Product Synonym Names

Type II inositol 3,4-bisphosphate 4-phosphatase; 3.1.3.66; Inositol polyphosphate 4-phosphatase type II; INPP4B

Clonality

Monoclonal

Clone Number

GDO-9

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

Liquid; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purity/Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution ratio. (lot specific)

Preparation and Storage

Store at -20 degree C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freez-thaw cycles.

Molecular Weight

104738 MW

OMIM

U96922 mRNA

3D Structure

ModBase 3D Structure for O15327

Immunogen

A synthesized peptide derived from human INPP4B

Product Categories/Family for anti-INPP4B antibody

Signal Transduction; Signaling Pathway; Lipid Signaling; lipid Phosphatases

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-INPP4B antibody

Flow Cytometry (FC), Immunohistochemistry (IHC), Western Blot (WB)

Application Notes for anti-INPP4B antibody

Dilute the sample so that the expected range of concentrations fall within the detection range of this kit.
If the expected range of concentration is unknown, a pilot test should be conducted to decide the optimal dilution ratio for your samples.
Some PubMed article(s) citing the expression level of this target are as follows: The labs internal QC testing used:
WB: 1:1000-1:2000
IHC: 1:50-1:200
FC: 1:50

Other Notes

Small volumes of anti-INPP4B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for INPP4B purchase

MBS1750078 is an antibody targeting INPP4B. Also known as Anti-INPP4B/Type Ii 4 Phosphatase Rabbit Monoclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for INPP4B. It may not necessarily be applicable to this product.

NCBI GI #

156104897

NCBI GeneID

8821

NCBI Accession #

NP_001095139.1

UniProt Primary Accession #

O15327

UniProt Secondary Accession #

Q2TAI2; Q5XLE7; Q6IN59; Q6PJB4

UniProt Related Accession #

O15327

GenBank Nucleotide #

NM_001101669.2

NCBI Official Full Name

type II inositol 3,4-bisphosphate 4-phosphatase isoform 1

NCBI Official Synonym Full Names

inositol polyphosphate-4-phosphatase type II B

NCBI Official Symbol

INPP4B

UniProt Protein Name

Type II inositol 3,4-bisphosphate 4-phosphatase

UniProt Synonym Protein Names

Inositol polyphosphate 4-phosphatase type II

Protein Family

Type II inositol 3,4-bisphosphate 4-phosphatase

UniProt Gene Name

INPP4B

NCBI Protein Information

type II inositol 3,4-bisphosphate 4-phosphatase

NCBI Summary for INPP4B

INPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme. [provided by RefSeq, Jul 2008]

UniProt Comments for INPP4B

Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate.

Research Articles on INPP4B

1. INPP4B acted as a tumour suppressor in human prostate cancer

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-INPP4B antibody

Products by Pathway	Pathway Diagram
3-phosphoinositide Degradation Pathway antibodies	3-phosphoinositide Degradation Pathway Diagram
3-phosphoinositide Degradation Pathway antibodies	3-phosphoinositide Degradation Pathway Diagram
Inositol Phosphate Metabolism Pathway antibodies	Inositol Phosphate Metabolism Pathway Diagram
Inositol Phosphate Metabolism Pathway antibodies	Inositol Phosphate Metabolism Pathway Diagram
Inositol Phosphate Metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => Myo-inositol Pathway antibodies	Inositol Phosphate Metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => Myo-inositol Pathway Diagram
Inositol Phosphate Metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => Myo-inositol Pathway antibodies	Inositol Phosphate Metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => Myo-inositol Pathway Diagram
Phosphatidylinositol Signaling System Pathway antibodies	Phosphatidylinositol Signaling System Pathway Diagram
Phosphatidylinositol Signaling System Pathway antibodies	Phosphatidylinositol Signaling System Pathway Diagram

Diseases associated with anti-INPP4B antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>5 publications with INPP4B and Neoplasms
Breast Neoplasms Antibodies	>3 publications with INPP4B and Breast Neoplasms
Nervous System Diseases Antibodies	>2 publications with INPP4B and Nervous System Diseases
Leukemia Antibodies	>2 publications with INPP4B and Leukemia
Lymphoma Antibodies	>2 publications with INPP4B and Lymphoma
Congenital Abnormalities Antibodies	>1 publications with INPP4B and Congenital Abnormalities
Immune System Diseases Antibodies	>1 publications with INPP4B and Immune System Diseases
Kidney Diseases Antibodies	>1 publications with INPP4B and Kidney Diseases
Drug Toxicity Antibodies	>1 publications with INPP4B and Drug Toxicity
Prostatic Neoplasms Antibodies	>1 publications with INPP4B and Prostatic Neoplasms

Organs/Tissues associated with anti-INPP4B antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>3 publications with INPP4B and Bone
Prostate Antibodies	>3 publications with INPP4B and Prostate
Kidney Antibodies	>2 publications with INPP4B and Kidney
Connective Tissue Antibodies	>1 publications with INPP4B and Connective Tissue
Liver Antibodies	>1 publications with INPP4B and Liver
Bone Marrow Antibodies	>1 publications with INPP4B and Bone Marrow
Muscle Antibodies	>1 publications with INPP4B and Muscle
Brain Antibodies	>1 publications with INPP4B and Brain