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ALAS1 Antibody – Rabbit Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1750118

Anti-Alas1/Alas H Rabbit Monoclonal Antibody MBS1750118. Tested in Immunofluroescence (IF), Immunocytochemistry (ICC), Western Blot (WB) applications. This antibody reacts with Human. More details

$210 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Alas1/Alas H, Monoclonal Antibody
Full Product Name
Anti-Alas1/Alas H Rabbit Monoclonal Antibody
Product Gene Name
Product Synonym Names
5-aminolevulinate synthase, nonspecific, mitochondrial; ALAS-H; 2.3.1.37; 5-aminolevulinic acid synthase 1; Delta-ALA synthase 1; Delta-aminolevulinate synthase 1; ALAS1; ALAS3, ALASH; OK/SW-cl.121
Clonality
Monoclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Affinity-chromatography
Concentration
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. (lot specific)
Preparation and Storage
Store at -20 degree C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight
70581 MW
OMIM
X56351 mRNA
3D Structure
ModBase 3D Structure for P13196
Immunogen
A synthesized peptide derived from human Alas1
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-ALAS1 antibody
Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB)
Application Notes for anti-ALAS1 antibody
Dilute the sample so that the expected range of concentrations fall within the detection range of this kit.
If the expected range of concentration is unknown, a pilot test should be conducted to decide the optimal dilution ratio for your samples.
Some PubMed article(s) citing the expression level of this target are as follows: The labs internal QC testing used
WB 1:500-1:2000
ICC/IF 1:50-1:200

Western Blot (WB) of anti-ALAS1 antibody

Western blot analysis of Alas1 expression in HepG2 cell lysate (MBS1750118).
Rabbit Anti-ALAS1 Monoclonal Antibody – Cat# MBS1750118

Other Notes

Small volumes of anti-ALAS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ALAS1 purchase

MBS1750118 is an antibody targeting ALAS1. Also known as Anti-Alas1/Alas H Rabbit Monoclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ALAS1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
5-aminolevulinate synthase, nonspecific, mitochondrial isoform 1
NCBI Official Synonym Full Names
5'-aminolevulinate synthase 1
NCBI Official Symbol
ALAS1
NCBI Official Synonym Symbols
ALAS; MIG4; ALAS3; ALASH; ALAS-H
UniProt Protein Name
5-aminolevulinate synthase, nonspecific, mitochondrial
UniProt Synonym Protein Names
5-aminolevulinic acid synthase 1; Delta-ALA synthase 1; Delta-aminolevulinate synthase 1
UniProt Gene Name
ALAS1
UniProt Synonym Gene Names
ALAS3; ALASH; ALAS-H
NCBI Protein Information
5-aminolevulinate synthase, nonspecific, mitochondrial

NCBI Summary for ALAS1

This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
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UniProt Comments for ALAS1

MiscellaneousThere are two delta-ALA synthases in vertebrates: an erythroid- specific form and one (housekeeping) which is expressed in all tissues.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ALAS1 antibody

 Reference Product  PubMed Publications
 ALAD antibody  >2 publications with ALAS1 and ALAD
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