• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Glucose Transporter 5 GLUT5 (SLC2A5) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS175118

Background: GLUT5(Glucose transporter 5), also known as SLC2A5, is a fructose transporter expressed on the apical border of enterocytes in the small intestine. The GLUT5 gene is located on chromosome 1. GLUT5 allows for fructose to be transported from the… More details

$210 / 0.01 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Glucose Transporter 5 GLUT5 (SLC2A5), Polyclonal Antibody
Full Product Name
Polyclonal Anti-SLC2A5 Antibody
Product Gene Name
anti-SLC2A5 antibody
Product Synonym Names
Background: GLUT5(Glucose transporter 5), also known as SLC2A5, is a fructose transporter expressed on the apical border of enterocytes in the small intestine. The GLUT5 gene is located on chromosome 1. GLUT5 allows for fructose to be transported from the intestinal lumen into the enterocyte by facilitated diffusion due to fructose's high concentration in the intestinal lumen. GLUT5 is also expressed in skeletal muscle, testis, kidney, fat tissue, and brain. Fructose malabsorption or Dietary Fructose Intolerance is a dietary disability of the small intestine, where the amount of fructose carrier in enterocytes is deficient. In humans the GLUT5 protein is encoded by the SLC2A5 gene.
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, Rat
Form/Format
Lyophilized
Purity/Purification
Immunogen affinity purified.
Specificity
No cross reactivity with other proteins.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
3D Structure
ModBase 3D Structure for Q9WV38
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of mouse Glucose Transporter 5 GLUT5 (232-251aa ALQTLRGWKDVHLEMEEIRK), different from the related rat sequence by two amino acids.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-SLC2A5 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Formalin
Application Notes for anti-SLC2A5 antibody
Western Blot
Concentration: 0.1-0.5ug/ml
Tested Species: Ms, Rat
Predicted Species: -
Antigen Retrieval: -

Immunohistochemistry (Paraffin-embedded Section):
Concentration: 0.5-1ug/ml
Tested Species: Ms, Rat
Predicted Species: -
Antigen Retrieval: By Heat

Immunohistochemistry (Frozen Section):
Concentration: 0.5-1ug/ml
Tested Species: Rat
Predicted Species: Ms
Antigen Retrieval: -

Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sects.
Other applications have not been tested.
Optimal dilutions should be determined by end users.

Western Blot (WB) of anti-SLC2A5 antibody

Anti-SLC2A5 antibody, PA1737, Western blotting
All lanes: Anti SLC2A5 at 0.5ug/ml
Lane 1: Rat Kidney Tissue Lysate at 50ug
Lane 2: Rat Liver Tissue Lysate at 50ug
Lane 3: Mouse Kidney Tissue Lysate at 50ug
Predicted bind size: 55KD
Observed bind size: 55KD
Rabbit Anti-SLC2A5 Polyclonal Antibody – Cat# MBS175118

Immunohistochemistry (IHC) of anti-SLC2A5 antibody

Anti-SLC2A5 antibody, IHC(P)
IHC(P): Rat Kidney Tissue
Rabbit Anti-SLC2A5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS175118

Immunohistochemistry (IHC) of anti-SLC2A5 antibody

Anti-SLC2A5 antibody, IHC(F)
IHC(F): Rat Intestine Tissue
Rabbit Anti-SLC2A5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS175118

Immunohistochemistry (IHC) of anti-SLC2A5 antibody

Figure 4. IHC analysis of GLUT5 using anti- GLUT5 antibody
GLUT5 was detected in paraffin-embedded section of mouse ggj3249 tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1ug/ml rabbit anti- GLUT5 Antibody overnight at 4 degree C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37 degree C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
Rabbit Anti-SLC2A5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS175118

Other Notes

Small volumes of anti-SLC2A5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC2A5 purchase

MBS175118 is an antibody targeting SLC2A5. Also known as Polyclonal Anti-SLC2A5 Antibody. Reactive in Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC2A5. It may not necessarily be applicable to this product.

NCBI GI #
341940783
NCBI GeneID
56485
NCBI Accession #
Q9WV38.2
UniProt Primary Accession #
Q9WV38
UniProt Secondary Accession #
Q8R1N7
UniProt Related Accession #
Q9WV38
NCBI Official Full Name
Solute carrier family 2, facilitated glucose transporter member 5
NCBI Official Synonym Full Names
solute carrier family 2 (facilitated glucose transporter), member 5
NCBI Official Symbol
Slc2a5
NCBI Official Synonym Symbols
Glut5; Slc5a; AI526984
UniProt Protein Name
Solute carrier family 2, facilitated glucose transporter member 5
UniProt Synonym Protein Names
Fructose transporter; Glucose transporter type 5, small intestine; GLUT-5
Protein Family
Solute carrier family
UniProt Gene Name
Slc2a5
UniProt Synonym Gene Names
Glut5; GLUT-5
UniProt Entry Name
GTR5_MOUSE
NCBI Protein Information
solute carrier family 2, facilitated glucose transporter member 5; GLUT-5; fructose transporter; glucose transporter type 5, small intestine

UniProt Comments for SLC2A5

GLUT5: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. Plays an important role in fructose absorption by the intestine. Expressed primarily in the jejunal region of the small intestine. Expressed at low levels in human kidney, skeletal muscle, adipocytes, microglial cells and in the human blood-brain barrier.

Protein type: Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral; Transporter

Cellular Component: membrane; apical plasma membrane; integral to membrane; plasma membrane

Molecular Function: transporter activity; fructose transmembrane transporter activity; glucose transmembrane transporter activity; transmembrane transporter activity; substrate-specific transmembrane transporter activity

Biological Process: transport; fructose transport; carbohydrate transport; glucose transport; transmembrane transport
Show more

Research Articles on SLC2A5

1. Fructose and GluT5 play an important role in regulating adipose differentiation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SLC2A5 antibody

 Products by Pathway  Pathway Diagram
 Carbohydrate Digestion And Absorption Pathway antibodies  Carbohydrate Digestion And Absorption Pathway Diagram
 Carbohydrate Digestion And Absorption Pathway antibodies  Carbohydrate Digestion And Absorption Pathway Diagram
 Class II GLUTs Pathway antibodies  Class II GLUTs Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Facilitative Na+-independent Glucose Transporters Pathway antibodies  Facilitative Na+-independent Glucose Transporters Pathway Diagram
 Glycogen Storage Diseases Pathway antibodies  Glycogen Storage Diseases Pathway Diagram
 Glycolysis And Gluconeogenesis Pathway antibodies  Glycolysis And Gluconeogenesis Pathway Diagram
 Hexose Transport Pathway antibodies  Hexose Transport Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram

Diseases associated with anti-SLC2A5 antibody

 Disease Name  Pubmed Publications
 Hypertension Antibodies  >9 publications with SLC2A5 and Hypertension
 Insulin Resistance Antibodies  >5 publications with SLC2A5 and Insulin Resistance
 Kidney Diseases Antibodies  >4 publications with SLC2A5 and Kidney Diseases
 Necrosis Antibodies  >4 publications with SLC2A5 and Necrosis
 Fibrosis Antibodies  >2 publications with SLC2A5 and Fibrosis
 Liver Diseases Antibodies  >2 publications with SLC2A5 and Liver Diseases
 Inflammation Antibodies  >2 publications with SLC2A5 and Inflammation
 Weight Gain Antibodies  >2 publications with SLC2A5 and Weight Gain
 Hypertrophy Antibodies  >2 publications with SLC2A5 and Hypertrophy
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with SLC2A5 and Prenatal Exposure Delayed Effects

Organs/Tissues associated with anti-SLC2A5 antibody

 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >24 publications with SLC2A5 and Intestine
 Kidney Antibodies  >9 publications with SLC2A5 and Kidney
 Liver Antibodies  >6 publications with SLC2A5 and Liver
 Brain Antibodies  >5 publications with SLC2A5 and Brain
 Heart Antibodies  >3 publications with SLC2A5 and Heart
 Testis Antibodies  >3 publications with SLC2A5 and Testis
 Lung Antibodies  >2 publications with SLC2A5 and Lung
 Stomach Antibodies  >2 publications with SLC2A5 and Stomach
 Embryonic Tissue Antibodies  >1 publications with SLC2A5 and Embryonic Tissue
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000