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Aquaporin 5 (AQP5) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS175122

Description: Rabbit IgG polyclonal antibody for Aquaporin-5(AQP5) detection. Tested with WB, IHC-P in Mouse, Rat.Background: Aquaporin 5, also known as AQP5, is a water channel protein. The aquaporins(AQPs) are a family of more than 10 homologous water… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Aquaporin 5 (AQP5), Polyclonal Antibody
Full Product Name
Anti-Aquaporin 5 antibody
Product Gene Name
anti-AQP5 antibody
Product Synonym Names
Aquaporin-5(AQP-5); aquaporin 5; AQP 5 antibody; AQP-5 antibody; AQP5 antibody; AQP5_HUMAN antibody; Aquaporin 5 antibody; Aquaporin-5 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Reacts with : Rat
Predicted to work with : Mouse
Form/Format
Lyophilized
Purity/Purification
Immunogen affinity purified.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
3D Structure
ModBase 3D Structure for Q9WTY4
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of mouse Aquaporin 5 (246-265aa EEDWEDHREERKKTIELTAH), identical to the related rat sequence.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-AQP5 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Application Notes for anti-AQP5 antibody
WB: Concentration: 0.1-0.5ug/mL ; Tested Species: Rat; Predicted Species: Mouse
IHC: Concentration: 0.5-0.1ug/mL; Tested Species: Rat; Predicted Species: Mouse; Antigen Retrieval: By Heat

Tested Species: In-house tested species with positive results
Predicted Species: Species predicted to be fit for the product based on sequence similarities
By Heat: Boiling the paraffin sections in 10mM citratebuffer , pH6.0, for 20 mins is required for the staining of formalin/paraffin sections
Other applicaitons have not been tested
Optimal dilutions should be determined by the end users.

Western Blot (WB) of anti-AQP5 antibody

Anti-Aquaporin 5 antibody, MBS175122, Western blotting
Working concentration: 0.5ug/ml
Lane 1: Rat Lung Tissue Lysate
Lane 2: Rat Testis Tissue Lysate
Rabbit Anti-AQP5 Polyclonal Antibody – Cat# MBS175122

Immunohistochemistry (IHC) of anti-AQP5 antibody

Anti-Aquaporin 5 antibody, MBS175122, IHC(P)
IHC(P): Rat Lung Tissue Lysate
Working concentration: 1ug/ml
Rabbit Anti-AQP5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS175122

Other Notes

Small volumes of anti-AQP5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AQP5 purchase

MBS175122 is an antibody targeting AQP5. Also known as Anti-Aquaporin 5 antibody. Reactive in Reacts with : Rat
Predicted to work with : Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AQP5. It may not necessarily be applicable to this product.

NCBI GI #
7387547
NCBI GeneID
11830
NCBI Accession #
Q9WTY4.1
UniProt Primary Accession #
Q9WTY4
UniProt Secondary Accession #
Q545H1
UniProt Related Accession #
Q9WTY4
NCBI Official Full Name
Aquaporin-5
NCBI Official Synonym Full Names
aquaporin 5
NCBI Official Symbol
Aqp5
UniProt Protein Name
Aquaporin-5
Protein Family
Aquaporin
UniProt Gene Name
Aqp5
UniProt Synonym Gene Names
AQP-5
UniProt Entry Name
AQP5_MOUSE
NCBI Protein Information
aquaporin-5; AQP-5

UniProt Comments for AQP5

AQP5: Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions. Belongs to the MIP/aquaporin (TC 1.A.8) family.

Protein type: Transporter; Transporter, aquaporin family; Membrane protein, integral; Membrane protein, multi-pass; Channel, misc.

Cellular Component: microvillus; membrane; endoplasmic reticulum; integral to plasma membrane; cell; apical plasma membrane; integral to membrane; plasma membrane; basal plasma membrane

Molecular Function: protein binding; transporter activity; water channel activity; glycerol channel activity

Biological Process: glycerol transport; camera-type eye morphogenesis; cellular water homeostasis; transport; carbon dioxide transport; cellular response to stress; water transport; transmembrane transport; saliva secretion
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Research Articles on AQP5

1. The co-regulation of pendrin and AQP5 membrane expression under chronic K(+)-deficiency indicates that these two molecules could cooperate as an osmosensor to rapidly detect and respond to alterations in luminal fluid osmolality.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AQP5 antibody

 Reference Product  PubMed Publications
 Sftpc antibody  >13 publications with AQP5 and Sftpc
 Aqp11 antibody  >11 publications with AQP5 and Aqp11
 Tnf antibody  >9 publications with AQP5 and Tnf
 Aqp12 antibody  >8 publications with AQP5 and Aqp12
 Scgb1a1 antibody  >5 publications with AQP5 and Scgb1a1
 Fgf7 antibody  >4 publications with AQP5 and Fgf7
 Trpv4 antibody  >4 publications with AQP5 and Trpv4

Pathways associated with anti-AQP5 antibody

 Products by Pathway  Pathway Diagram
 Aquaporin-mediated Transport Pathway antibodies  Aquaporin-mediated Transport Pathway Diagram
 Passive Transport By Aquaporins Pathway antibodies  Passive Transport By Aquaporins Pathway Diagram
 Salivary Secretion Pathway antibodies  Salivary Secretion Pathway Diagram
 Salivary Secretion Pathway antibodies  Salivary Secretion Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram

Diseases associated with anti-AQP5 antibody

 Disease Name  Pubmed Publications
 Edema Antibodies  >55 publications with AQP5 and Edema
 Disease Models, Animal Antibodies  >40 publications with AQP5 and Disease Models, Animal
 Inflammation Antibodies  >30 publications with AQP5 and Inflammation
 Nervous System Diseases Antibodies  >13 publications with AQP5 and Nervous System Diseases
 Necrosis Antibodies  >12 publications with AQP5 and Necrosis
 Hyperplasia Antibodies  >10 publications with AQP5 and Hyperplasia
 Kidney Diseases Antibodies  >10 publications with AQP5 and Kidney Diseases
 Lung Neoplasms Antibodies  >9 publications with AQP5 and Lung Neoplasms
 Liver Diseases Antibodies  >4 publications with AQP5 and Liver Diseases
 Weight Loss Antibodies  >4 publications with AQP5 and Weight Loss

Organs/Tissues associated with anti-AQP5 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >152 publications with AQP5 and Lung
 Salivary Gland Antibodies  >142 publications with AQP5 and Salivary Gland
 Eye Antibodies  >58 publications with AQP5 and Eye
 Skin Antibodies  >22 publications with AQP5 and Skin
 Muscle Antibodies  >20 publications with AQP5 and Muscle
 Uterus Antibodies  >19 publications with AQP5 and Uterus
 Stomach Antibodies  >14 publications with AQP5 and Stomach
 Testis Antibodies  >8 publications with AQP5 and Testis
 Bladder Antibodies  >8 publications with AQP5 and Bladder
 Thyroid Antibodies  >7 publications with AQP5 and Thyroid
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