Rabbit Anti-CD147 Polyclonal Antibody – Cat# MBS1751224

Figure 1. Flow Cytometry analysis of A549 cells using anti-Human CD147/Emmprin antibody.
Overlay histogram showing A549 cells stained with A00248-Dyl488 (Blue line).The cells were blocked with 10% normal goat serum. And then incubated with rabbit anti-Human CD147/Emmprin Antibody for 30 min at 20 degree C. DyLight® 488 conjugated goat anti-rabbit IgG (5-10ug/1x106 cells) was used as secondary antibody for 30 minutes at 20 degree C. Isotype control antibody (Green line) was rabbit IgG (1ug/1x106) used under the same conditions. Unlabelled sample (Red line) was also used as a control.

CD147 Antibody – Rabbit Polyclonal

Name: CD147 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS1751224
Price: 630 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1751224

Emmprin, extracellular matrix metalloproteinase inducer, also known as Emmprin (BSG) or cluster of differentiation 147 (CD147) is a protein that in humans is encoded by the Emmprin gene. The human BSG gene is mapped to 19p13.3. This protein is a determinant… More details

$630 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD147/Emmprin, Polyclonal Antibody

Full Product Name

Anti-Human CD147/Emmprin DyLight 488 conjugated Antibody

Product Gene Name

anti-CD147 antibody

Product Synonym Gene Name

BSG

Product Synonym Names

Rabbit IgG Polyclonal Anti-Human CD147/Emmprin Antibody DyLight 488 Conjugated, Flow Validated; Basigin; 5F7; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSF; CD147; BSG; UNQ6505/PRO21383

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Liquid

Purity/Purification

Immunogen Affinity Purified

Specificity

No cross reactivity with other proteins.

Preparation and Storage

Store at 2-8 degree C for one year. Protect from light. Do not freeze.

Molecular Weight

29,221 Da

3D Structure

ModBase 3D Structure for P35613

Immunogen

E Coli-derived human CD147/Emmprin recombinant protein (Position: E138-A323). Human CD147/Emmprin shares 51.1% and 51.9% amino acid (aa) sequence identity with mouse and rat CD147/Emmprin, respectively.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-CD147 antibody

Flow Cytometry (FC/FACS)

Application Notes for anti-CD147 antibody

FC/FACS: 1-3ug/1x106 cells

Product References and Citations for anti-CD147 antibody

1. Guo, H., Majmudar, G., Jensen, T. C., Biswas, C., Toole, B. P., Gordon, M. K.Characterization of the gene for human EMMPRIN, a tumor cell surface inducer of matrix metalloproteinases.Gene 220: 99-108, 1998. 2. Zhou, S., Zhou, H., Walian, P. J., Jap, B. K.CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production.

Other Notes

Small volumes of anti-CD147 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD147 purchase

MBS1751224 is an antibody targeting CD147. Also known as Anti-Human CD147/Emmprin DyLight 488 conjugated Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CD147. It may not necessarily be applicable to this product.

NCBI GI #

1016080631

NCBI GeneID

682

NCBI Accession #

NP_001309172.1

UniProt Primary Accession #

P35613

UniProt Secondary Accession #

Q7Z796; Q8IZL7; A6NJW1; D3YLG5

UniProt Related Accession #

P35613

GenBank Nucleotide #

NM_001322243.1

NCBI Official Full Name

basigin isoform 2

NCBI Official Synonym Full Names

basigin (Ok blood group)

NCBI Official Symbol

BSG

NCBI Official Synonym Symbols

OK; 5F7; TCSF; CD147; EMPRIN; EMMPRIN; SLC7A11

UniProt Protein Name

Basigin

UniProt Synonym Protein Names

5F7; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSF; CD_antigen: CD147

UniProt Gene Name

BSG

UniProt Synonym Gene Names

EMMPRIN; TCSF

NCBI Protein Information

basigin

NCBI Summary for CD147

The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for CD147

Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3, SLC16A8, SLC16A11 and SLC16A12 to the plasma membrane (PubMed:21778275). Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.

Research Articles on CD147

1. these findings show that CD147 is a novel and key mediator of IL-22-induced psoriatic alterations in the epidermis and might be a therapeutic target in patients with psoriasis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD147 antibody

Reference Product	PubMed Publications
SLC16A4 antibody	>27 publications with CD147 and SLC16A4
MMP1 antibody	>6 publications with CD147 and MMP1
SLC16A3 antibody	>5 publications with CD147 and SLC16A3
SLC16A1 antibody	>2 publications with CD147 and SLC16A1
PPIL2 antibody	>1 publications with CD147 and PPIL2
AJAP1 antibody	>1 publications with CD147 and AJAP1
UBC antibody	>1 publications with CD147 and UBC

Pathways associated with anti-CD147 antibody

Products by Pathway	Pathway Diagram
Basigin Interactions Pathway antibodies	Basigin Interactions Pathway Diagram
Cell Surface Interactions At The Vascular Wall Pathway antibodies	Cell Surface Interactions At The Vascular Wall Pathway Diagram
Degradation Of The Extracellular Matrix Pathway antibodies	Degradation Of The Extracellular Matrix Pathway Diagram
Extracellular Matrix Organization Pathway antibodies	Extracellular Matrix Organization Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Integrin Cell Surface Interactions Pathway antibodies	Integrin Cell Surface Interactions Pathway Diagram
Matrix Metalloproteinases Pathway antibodies	Matrix Metalloproteinases Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Proton-coupled Monocarboxylate Transport Pathway antibodies	Proton-coupled Monocarboxylate Transport Pathway Diagram
Pyruvate Metabolism Pathway antibodies	Pyruvate Metabolism Pathway Diagram

Diseases associated with anti-CD147 antibody

Disease Name	Pubmed Publications
Carcinoma Antibodies	>184 publications with CD147 and Carcinoma
Neoplasm Metastasis Antibodies	>101 publications with CD147 and Neoplasm Metastasis
Adenocarcinoma Antibodies	>85 publications with CD147 and Adenocarcinoma
Neoplasm Invasiveness Antibodies	>83 publications with CD147 and Neoplasm Invasiveness
Inflammation Antibodies	>58 publications with CD147 and Inflammation
Liver Diseases Antibodies	>49 publications with CD147 and Liver Diseases
Carcinoma, Squamous Cell Antibodies	>48 publications with CD147 and Carcinoma, Squamous Cell
Breast Neoplasms Antibodies	>48 publications with CD147 and Breast Neoplasms
Carcinoma, Hepatocellular Antibodies	>40 publications with CD147 and Carcinoma, Hepatocellular
Liver Neoplasms Antibodies	>39 publications with CD147 and Liver Neoplasms

Organs/Tissues associated with anti-CD147 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>381 publications with CD147 and Blood
Brain Antibodies	>191 publications with CD147 and Brain
Vascular Antibodies	>114 publications with CD147 and Vascular
Muscle Antibodies	>66 publications with CD147 and Muscle
Liver Antibodies	>64 publications with CD147 and Liver
Lung Antibodies	>59 publications with CD147 and Lung
Nerve Antibodies	>52 publications with CD147 and Nerve
Bone Antibodies	>45 publications with CD147 and Bone
Eye Antibodies	>44 publications with CD147 and Eye
Lymph Antibodies	>41 publications with CD147 and Lymph