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NFATC4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1751428

Nuclear factor of activated T-cells, cytoplasmic 4 is a protein that in humans is encoded by the NFATC4 gene. This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
NFATC4, Polyclonal Antibody
Full Product Name
Anti-Human NFATC4 DyLight 550 conjugated Antibody
Product Gene Name
Product Synonym Names
Rabbit IgG Polyclonal Anti-Human NFATC4 Antibody DyLight 550 Conjugated, Flow Validated; Nuclear factor of activated T-cells, cytoplasmic 4; NF-ATc4; NFATc4; T-cell transcription factor NFAT3; NF-AT3; NFATC4; NFAT3; Nuclear factor of activated T-cells 4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Immunogen Affinity Purified
Specificity
No cross reactivity with other proteins.
Preparation and Storage
Store at 2-8 degree C for one year. Protect from light. Do not freeze.
Molecular Weight
101,680 Da
3D Structure
ModBase 3D Structure for Q14934
Immunogen
E Coli-derived human NFATC4 recombinant protein (Position: Q413-D522).
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-NFATC4 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-NFATC4 antibody
FC/FACS: 1-3ug/1x106 cells

Product References and Citations for anti-NFATC4 antibody

1. Hoey T, Sun YL, Williamson K, Xu X (May 1995). "Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins". Immunity. 2 (5): 461-72. 2. Yang T, Davis RJ, Chow CW (Oct 2001). "Requirement of two NFATc4 transactivation domains for CBP potentiation". The Journal of Biological Chemistry. 276 (43): 39569-76.

Other Notes

Small volumes of anti-NFATC4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NFATC4 purchase

MBS1751428 is an antibody targeting NFATC4. Also known as Anti-Human NFATC4 DyLight 550 conjugated Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NFATC4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
nuclear factor of activated T-cells, cytoplasmic 4 isoform 1
NCBI Official Synonym Full Names
nuclear factor of activated T cells 4
NCBI Official Symbol
NFATC4
NCBI Official Synonym Symbols
NFAT3; NF-AT3; NF-ATC4
UniProt Protein Name
Nuclear factor of activated T-cells, cytoplasmic 4
UniProt Synonym Protein Names
T-cell transcription factor NFAT3; NF-AT3
UniProt Gene Name
NFATC4
UniProt Synonym Gene Names
NFAT3; NF-ATc4; NFATc4; NF-AT3
NCBI Protein Information
nuclear factor of activated T-cells, cytoplasmic 4

NCBI Summary for NFATC4

This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
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UniProt Comments for NFATC4

Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 and IL-4. Transcriptionally repressed by estrogen receptors; this inhibition is further enhanced by estrogen. Increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. May play an important role in myotube differentiation. May play a critical role in cardiac development and hypertrophy. May play a role in deafferentation-induced apoptosis of sensory neurons.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NFATC4 antibody

 Reference Product  PubMed Publications
 GATA4 antibody  >8 publications with NFATC4 and GATA4
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