• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

ADO Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1751433

Human thiol dioxygenases include cysteine dioxygenase (CDO) and cysteamine (2-aminoethanethiol) dioxygenase (ADO). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine. It is demonstrated that mouse… More details

$630 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ADO, Polyclonal Antibody
Full Product Name
Anti-Human ADO DyLight 488 conjugated Antibody
Product Gene Name
anti-ADO antibody
Product Synonym Names
Rabbit IgG Polyclonal Anti-Human ADO Antibody DyLight 488 Conjugated, Flow Validated; 2-aminoethanethiol dioxygenase; Cysteamine dioxygenase; ADO; C10orf22
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Liquid
Purity/Purification
Immunogen Affinity Purified
Specificity
No cross reactivity with other proteins.
Preparation and Storage
Store at 2-8 degree C for one year. Protect from light. Do not freeze.
Molecular Weight
29,751 Da
3D Structure
ModBase 3D Structure for Q96SZ5
Immunogen
E Coli-derived human ADO recombinant protein (Position: E49-E261). Human ADO shares 90.1% amino acid (aa) sequence identity with mouse ADO.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-ADO antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-ADO antibody
FC/FACS: 1-3ug/1x106 cells

Flow Cytometry (FC/FACS) of anti-ADO antibody

Figure 1. Flow Cytometry analysis of A549 cells using anti-Human ADO antibody.
Overlay histogram showing A549 cells stained with A02700-Dyl488 (Blue line).The cells were blocked with 10% normal goat serum. And then incubated with rabbit anti-Human ADO Antibody for 30 min at 20 degree C. DyLight® 488 conjugated goat anti-rabbit IgG (5-10ug/1x106 cells) was used as secondary antibody for 30 minutes at 20 degree C. Isotype control antibody (Green line) was rabbit IgG (1ug/1x106) used under the same conditions. Unlabelled sample (Red line) was also used as a control.
Rabbit Anti-ADO Polyclonal Antibody – Cat# MBS1751433

Product References and Citations for anti-ADO antibody

1. Dominy, J. E., Jr., Simmons, C. R., Hirschberger, L. L., Hwang, J., Coloso, R. M., Stipanuk, M. H. Discovery and characterization of a second mammalian thiol dioxygenase, cysteamine dioxygenase.J. Biol. Chem. 282: 25189-25198, 2007.

Other Notes

Small volumes of anti-ADO antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ADO purchase

MBS1751433 is an antibody targeting ADO. Also known as Anti-Human ADO DyLight 488 conjugated Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ADO. It may not necessarily be applicable to this product.

NCBI GI #
62177110
NCBI GeneID
84890
NCBI Accession #
NP_116193.2
UniProt Primary Accession #
Q96SZ5
UniProt Secondary Accession #
B1AL29
UniProt Related Accession #
Q96SZ5
GenBank Nucleotide #
NM_032804.5
NCBI Official Full Name
2-aminoethanethiol dioxygenase
NCBI Official Synonym Full Names
2-aminoethanethiol dioxygenase
NCBI Official Symbol
ADO
NCBI Official Synonym Symbols
C10orf22
UniProt Protein Name
2-aminoethanethiol dioxygenase
UniProt Synonym Protein Names
Cysteamine dioxygenase
Protein Family
2-aminoethanethiol dioxygenase
UniProt Gene Name
ADO
UniProt Synonym Gene Names
C10orf22
NCBI Protein Information
2-aminoethanethiol dioxygenase

NCBI Summary for ADO

Human thiol dioxygenases include cysteine dioxygenase (CDO; MIM 603943) and cysteamine (2-aminoethanethiol) dioxygenase (ADO; EC 1.13.11.19). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine (Dominy et al., 2007 [PubMed 17581819]).[supplied by OMIM, Mar 2008]
Show more

Research Articles on ADO

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ADO antibody

 Reference Product  PubMed Publications
 CSAD antibody  >1 publications with ADO and CSAD

Pathways associated with anti-ADO antibody

 Products by Pathway  Pathway Diagram
 Taurine And Hypotaurine Metabolism Pathway antibodies  Taurine And Hypotaurine Metabolism Pathway Diagram
 Taurine And Hypotaurine Metabolism Pathway antibodies  Taurine And Hypotaurine Metabolism Pathway Diagram

Organs/Tissues associated with anti-ADO antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >506 publications with ADO and Blood
 Vascular Antibodies  >228 publications with ADO and Vascular
 Muscle Antibodies  >227 publications with ADO and Muscle
 Brain Antibodies  >146 publications with ADO and Brain
 Lung Antibodies  >115 publications with ADO and Lung
 Kidney Antibodies  >99 publications with ADO and Kidney
 Liver Antibodies  >75 publications with ADO and Liver
 Bone Antibodies  >57 publications with ADO and Bone
 Skin Antibodies  >48 publications with ADO and Skin
 Intestine Antibodies  >34 publications with ADO and Intestine
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000