Rabbit Anti-CD80 Polyclonal Antibody – Cat# MBS175144

Anti-CD80 antibody, MBS175144, Western blotting
Lane 1: Recombinant Human CD80 Protein 10ng
Lane 2: Recombinant Human CD80 Protein 5ng
Lane 3: Recombinant Human CD80 Protein 2.5ng

CD80 Antibody – Rabbit Polyclonal

Name: CD80 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS175144
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS175144

Description: Rabbit IgG polyclonal antibody for T-lymphocyte activation antigen CD80(CD80) detection. Tested with WB in Human.Background: Cluster of Differentiation 80(also CD80 and B7-1) is a protein found on activated B cells and monocytes that provides a… More details

$210 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD80, Polyclonal Antibody

Full Product Name

Anti-CD80 antibody

Product Gene Name

anti-CD80 antibody

Product Synonym Names

T-lymphocyte activation antigen CD80; CD80 molecule; Activation B7 1 antigen antibody; Activation B7-1 antigen antibody; Activation B71 antigen antibody; B lymphocyte activation antigen B7 antibody; B7 antibody; B7-1 antibody; B7-1 antigen antibody; BB1 antibody; CD 80 antibody; CD28 antigen ligand 1 antibody; CD28 antigen ligand 1 B7 1 antigen antibody; CD28 antigen ligand 1 B71 antigen antibody; CD28LG antibody; CD28LG1 antibody; CD80 antibody; CD80 antigen antibody; CD80 antigen precursor antibody; CD80 molecule antibody; CD80_HUMAN antibody; Costimulatory factor CD80 antibody; CTLA 4 counter receptor B7.1 antibody; CTLA-4 counter-receptor B7.1 antibody; LAB 7 antibody; LAB7 antibody; T lymphocyte activation antigen CD80 antibody; T-lymphocyte activation antigen CD80 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Lyophilized

Purity/Purification

Immunogen affinity purified.

Preparation and Storage

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Molecular Weight

18,761 Da

OMIM

112203

3D Structure

ModBase 3D Structure for P33681

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human CD80 (57-71aa EELAQTRIYWQKEKK).

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-CD80 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-CD80 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD80 purchase

MBS175144 is an antibody targeting CD80. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CD80. It may not necessarily be applicable to this product.

NCBI GI #

461606

NCBI GeneID

941

NCBI Accession #

P33681.1

UniProt Primary Accession #

P33681

UniProt Secondary Accession #

Q5DTA9; Q5DTB0

UniProt Related Accession #

P33681

NCBI Official Full Name

T-lymphocyte activation antigen CD80

NCBI Official Synonym Full Names

CD80 molecule

NCBI Official Symbol

CD80

NCBI Official Synonym Symbols

B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1

UniProt Protein Name

T-lymphocyte activation antigen CD80

UniProt Synonym Protein Names

Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD_antigen: CD80

Protein Family

T-lymphocyte activation antigen

UniProt Gene Name

CD80

UniProt Synonym Gene Names

CD28LG; CD28LG1; LAB7; B7

UniProt Entry Name

CD80_HUMAN

NCBI Protein Information

T-lymphocyte activation antigen CD80; activation B7-1 antigen; costimulatory factor CD80; CTLA-4 counter-receptor B7.1; B-lymphocyte activation antigen B7; costimulatory molecule variant IgV-CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)

NCBI Summary for CD80

The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011]

UniProt Comments for CD80

CD80: Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.

Protein type: Membrane protein, integral; Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 3q13.3-q21

Cellular Component: cell surface; integral to membrane; plasma membrane; external side of plasma membrane

Molecular Function: protein binding; coreceptor activity

Biological Process: epidermal growth factor receptor signaling pathway; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; viral reproduction; T cell activation; positive regulation of signal transduction; positive regulation of interleukin-2 biosynthetic process; positive regulation of transcription, DNA-dependent; positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process; positive regulation of peptidyl-tyrosine phosphorylation; cell-cell signaling; T cell costimulation; innate immune response; positive regulation of alpha-beta T cell proliferation; positive regulation of T-helper 1 cell differentiation

Research Articles on CD80

1. Expression of costimulatory molecules CD80/86 is an absolute requirement for efficient CD8 T cell priming by adenoviral vectors.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD80 antibody

Reference Product	PubMed Publications
CD86 antibody	>4647 publications with CD80 and CD86
CD4 antibody	>2101 publications with CD80 and CD4
CD28 antibody	>1801 publications with CD80 and CD28
CTLA4 antibody	>1008 publications with CD80 and CTLA4
ICAM1 antibody	>414 publications with CD80 and ICAM1
PRF1 antibody	>62 publications with CD80 and PRF1
IFNG antibody	>6 publications with CD80 and IFNG
CSF2 antibody	>2 publications with CD80 and CSF2

Pathways associated with anti-CD80 antibody

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Allograft Rejection Pathway antibodies	Allograft Rejection Pathway Diagram
Allograft Rejection Pathway antibodies	Allograft Rejection Pathway Diagram
Allograft Rejection Pathway antibodies	Allograft Rejection Pathway Diagram
Autoimmune Thyroid Disease Pathway antibodies	Autoimmune Thyroid Disease Pathway Diagram
Autoimmune Thyroid Disease Pathway antibodies	Autoimmune Thyroid Disease Pathway Diagram
CD28 Co-stimulation Pathway antibodies	CD28 Co-stimulation Pathway Diagram
CD28 Dependent PI3K/Akt Signaling Pathway antibodies	CD28 Dependent PI3K/Akt Signaling Pathway Diagram
CD28 Dependent Vav1 Pathway antibodies	CD28 Dependent Vav1 Pathway Diagram
CTLA4 Inhibitory Signaling Pathway antibodies	CTLA4 Inhibitory Signaling Pathway Diagram

Diseases associated with anti-CD80 antibody

Disease Name	Pubmed Publications
Necrosis Antibodies	>1099 publications with CD80 and Necrosis
Inflammation Antibodies	>728 publications with CD80 and Inflammation
Neoplasms, Experimental Antibodies	>376 publications with CD80 and Neoplasms, Experimental
Nervous System Diseases Antibodies	>342 publications with CD80 and Nervous System Diseases
Lung Diseases Antibodies	>301 publications with CD80 and Lung Diseases
Liver Diseases Antibodies	>221 publications with CD80 and Liver Diseases
Kidney Diseases Antibodies	>149 publications with CD80 and Kidney Diseases
Lung Neoplasms Antibodies	>110 publications with CD80 and Lung Neoplasms
Neoplasm Metastasis Antibodies	>81 publications with CD80 and Neoplasm Metastasis
Breast Neoplasms Antibodies	>80 publications with CD80 and Breast Neoplasms

Organs/Tissues associated with anti-CD80 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>5864 publications with CD80 and Blood
Lymph Node Antibodies	>576 publications with CD80 and Lymph Node
Lung Antibodies	>412 publications with CD80 and Lung
Thymus Antibodies	>177 publications with CD80 and Thymus
Tonsil Antibodies	>39 publications with CD80 and Tonsil
Connective Tissue Antibodies	>33 publications with CD80 and Connective Tissue
Mammary Gland Antibodies	>4 publications with CD80 and Mammary Gland