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CCR2 Antibody – Rabbit Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1751918

Rabbit IgG Monoclonal antibody for CCR2/CKR detection. Tested positive for IHC, FC, IP in Human; Mouse More details

$210 / 0.03 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CCR2/CKR2, Monoclonal Antibody
Full Product Name
Anti-CCR2/CKR2
Product Gene Name
Product Synonym Gene Name
CKR2
Clonality
Monoclonal
Isotype
IgG
Clone Number
AOF-3
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA
Purity/Purification
Affinity-Chromatography
Concentration
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. (lot specific)
Specificity
No cross reactivity with other proteins.
Preparation and Storage
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
3D Structure
ModBase 3D Structure for P41597
Immunogen
A synthesized peptide derived from human CCR2/CKR2 Receptor.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-CCR2 antibody
Flow Cytometry (FC), Immunoprecipitation (IP), Immunohistochemistry (IHC)
Application Notes for anti-CCR2 antibody
IHC: 1:50-1:200
IP: 1:50
FC: 1:100

Immunohistochemistry (IHC) of anti-CCR2 antibody

Immunohistochemical analysis of paraffin-embedded human tonsil, using CCR2/CKR2.
Rabbit Anti-CCR2 Monoclonal Antibody – Cat# MBS1751918

Other Notes

Small volumes of anti-CCR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCR2 purchase

MBS1751918 is an antibody targeting CCR2. Also known as Anti-CCR2/CKR2. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CCR2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
C-C chemokine receptor type 2 isoform A
NCBI Official Synonym Full Names
C-C motif chemokine receptor 2
NCBI Official Symbol
CCR2
NCBI Official Synonym Symbols
CKR2; CCR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2
UniProt Protein Name
C-C chemokine receptor type 2
UniProt Synonym Protein Names
Monocyte chemoattractant protein 1 receptor; MCP-1-R; CD_antigen: CD192
UniProt Gene Name
CCR2
UniProt Synonym Gene Names
CMKBR2; C-C CKR-2; CC-CKR-2; CCR-2; CCR2; MCP-1-R
NCBI Protein Information
C-C chemokine receptor type 2

NCBI Summary for CCR2

The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. [provided by RefSeq, Aug 2017]
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UniProt Comments for CCR2

Receptor for the CCL2, CCL7 and CCL13 chemokines (PubMed:23408426). Receptor for the beta-defensin DEFB106A/DEFB106B (PubMed:23938203). Transduces a signal by increasing intracellular calcium ion levels (). Upon CCL2 ligation, mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (Probable).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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