Rabbit Anti-CCR10 Polyclonal Antibody – Cat# MBS175255

Anti-GPR2/CCR10 antibody, MBS175255, Western blotting
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GPR2/CCR10 (CCR10) Antibody – Rabbit Polyclonal

Name: CCR10 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS175255
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS175255

Description: Rabbit IgG polyclonal antibody for C-C chemokine receptor type 10(CCR10) detection. Tested with WB in Human, Mouse, Rat.Background: CCR10, C-C chemokine receptor type 10 is a protein that in humans is encoded by the CCR10 gene. CCR10 is… More details

$210 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GPR2/CCR10, Polyclonal Antibody

Full Product Name

Anti-GPR2/CCR10 antibody

Product Gene Name

anti-CCR10 antibody

Product Synonym Names

C-C chemokine receptor type 10(C-C CKR-10/CC-CKR-10/CCR-10); chemokine(C-C motif) receptor 10; C C chemokine receptor type 10 antibody; C C CKR 10 antibody; C-C chemokine receptor type 10 antibody; C-C CKR-10 antibody; CC chemokine receptor 10 antibody; CC CKR 10 antibody; CC-CKR-10 antibody; CCR 10 antibody; CCR-10 antibody; CCR10 antibody; CCR10_HUMAN antibody; Chemokine(C C motif) receptor 10 antibody; G protein coupled receptor 2 antibody; G protein-coupled receptor 2 antibody; G-protein coupled receptor 2 antibody; GPR 2 antibody; GPR2 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

Lyophilized

Purity/Purification

Immunogen affinity purified.

Preparation and Storage

At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Molecular Weight

38,416 Da

OMIM

600240

3D Structure

ModBase 3D Structure for P46092

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human GPR2/CCR10 (312-327aa FLGLRFRQDLRRLLRG), different from the related rat and mouse sequences by one amino acid.

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-CCR10 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-CCR10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCR10 purchase

MBS175255 is an antibody targeting CCR10. Also known as Anti-GPR2/CCR10 antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CCR10. It may not necessarily be applicable to this product.

NCBI GI #

62298314

NCBI GeneID

2826

NCBI Accession #

P46092.3

UniProt Primary Accession #

P46092

UniProt Secondary Accession #

Q4V749; Q6T7X2; Q9NZG2

UniProt Related Accession #

P46092

NCBI Official Full Name

C-C chemokine receptor type 10

NCBI Official Synonym Full Names

chemokine (C-C motif) receptor 10

NCBI Official Symbol

CCR10

NCBI Official Synonym Symbols

GPR2

UniProt Protein Name

C-C chemokine receptor type 10

UniProt Synonym Protein Names

G-protein coupled receptor 2

Protein Family

C-C chemokine receptor

UniProt Gene Name

CCR10

UniProt Synonym Gene Names

GPR2; C-C CKR-10; CC-CKR-10; CCR-10

UniProt Entry Name

CCR10_HUMAN

NCBI Protein Information

C-C chemokine receptor type 10; CCR-10; CC-CKR-10; C-C CKR-10; CC chemokine receptor 10; G protein-coupled receptor 2; G-protein coupled receptor 2

NCBI Summary for CCR10

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]

UniProt Comments for CCR10

CCR10: Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR

Chromosomal Location of Human Ortholog: 17q21.1-q21.3

Cellular Component: cell surface; integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; C-C chemokine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; immune response; chemotaxis

Research Articles on CCR10

1. low CCL27/CCR10 and CXCL12/CXCR4 intratumoral mRNA ratios are associated with melanoma progression

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CCR10 antibody

Reference Product	PubMed Publications
CCL27 antibody	>60 publications with CCR10 and CCL27
CCL28 antibody	>49 publications with CCR10 and CCL28
CXCL12 antibody	>20 publications with CCR10 and CXCL12
CCL25 antibody	>18 publications with CCR10 and CCL25
CCL21 antibody	>13 publications with CCR10 and CCL21
CCL19 antibody	>12 publications with CCR10 and CCL19
CCL7 antibody	>3 publications with CCR10 and CCL7
CXCL13 antibody	>2 publications with CCR10 and CXCL13
CCL13 antibody	>1 publications with CCR10 and CCL13

Pathways associated with anti-CCR10 antibody

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram

Diseases associated with anti-CCR10 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>106 publications with CCR10 and Inflammation
Necrosis Antibodies	>23 publications with CCR10 and Necrosis
Colitis Antibodies	>7 publications with CCR10 and Colitis
Drug-Related Side Effects and Adverse Reactions Antibodies	>6 publications with CCR10 and Drug-Related Side Effects and Adverse Reactions
Sclerosis Antibodies	>4 publications with CCR10 and Sclerosis
Graft vs Host Disease Antibodies	>3 publications with CCR10 and Graft vs Host Disease
Heart Failure Antibodies	>2 publications with CCR10 and Heart Failure
Movement Disorders Antibodies	>2 publications with CCR10 and Movement Disorders
Poisoning Antibodies	>1 publications with CCR10 and Poisoning
Cardiomegaly Antibodies	>1 publications with CCR10 and Cardiomegaly

Organs/Tissues associated with anti-CCR10 antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>18 publications with CCR10 and Bone
Embryonic Tissue Antibodies	>6 publications with CCR10 and Embryonic Tissue
Kidney Antibodies	>5 publications with CCR10 and Kidney
Brain Antibodies	>4 publications with CCR10 and Brain
Mixed Antibodies	>3 publications with CCR10 and Mixed
Connective Tissue Antibodies	>2 publications with CCR10 and Connective Tissue
Pancreas Antibodies	>1 publications with CCR10 and Pancreas
Testis Antibodies	>1 publications with CCR10 and Testis
Eye Antibodies	>1 publications with CCR10 and Eye