RBMS3 Antibody – Rabbit Polyclonal

Description: Rabbit IgG polyclonal antibody for RBMS3 detection. Tested with WB, IHC-P, Direct ELISA in Human; Mouse; Rat.

Background: RNA-binding motif, single-stranded-interacting protein 3 is a protein that in humans is encoded by the RBMS3 gene. It is mapped to 3p24.1. This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

1. Penkov, D., Ni, R., Else, C., Pinol-Roma, S., Ramirez, F., Tanaka, S. Cloning of a human gene closely related to the genes coding for the c-myc single-strand binding proteins. Gene 243: 27-36, 2000. 2. Kanaoka, Y., Nojima, H. SCR: novel human suppressors of cdc2/cdc13 mutants of Schizosaccharomyces pombe harbour motifs for RNA binding proteins. Nucleic Acids Res. 22: 2687-2693, 1994. 3. Negishi, Y., Nishita, Y., Saegusa, Y., Kakizaki, I., Galli, I., Kihara, F., Tamai, K., Miyajima, N., Iguchi-Ariga, S. M. M., Ariga, H. Identification and cDNA cloning of single-stranded DNA binding proteins that interact with the region upstream of the human c-myc gene. Oncogene 9: 1133-1143, 1994.

Small volumes of anti-RBMS3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS1752553 is an antibody targeting RBMS3. Reactive in Human, Mouse, Rat. Host: Rabbit.