Rabbit Anti-IFT88 Polyclonal Antibody – Cat# MBS1753143

IFT88 Antibody – Rabbit Polyclonal

Name: IFT88 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS1753143
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1753143

Description: Rabbit IgG polyclonal antibody for IFT88 detection. Tested with WB, IHC-P, ICC/IF, FCM, Direct ELISA in Human; Mouse; Rat.Background: Intraflagellar transport protein 88 homolog is a protein that in humans is encoded by the IFT88 gene. It is… More details

$210 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IFT88, Polyclonal Antibody

Full Product Name

Anti-IFT88 Antibody

Product Gene Name

anti-IFT88 antibody

Product Synonym Names

Intraflagellar transport protein 88 homolog; Recessive polycystic kidney disease protein Tg737 homolog; Tetratricopeptide repeat protein 10; TPR repeat protein 10; IFT88; TG737; TTC10

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

Lyophilized
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purity/Purification

Immunogen affinity purified.

Specificity

No cross reactivity with other proteins.

Preparation and Storage

Store at -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen store at -20 degree C for a longer time. Avoid repeated freezing and thawing.

OMIM

600595

3D Structure

ModBase 3D Structure for Q13099

Immunogen

E Coli-derived human IFT88 recombinant protein (Position: E198-K814).

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Applications Tested/Suitable for anti-IFT88 antibody

Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS), Direct ELISA (EIA)

Application Notes for anti-IFT88 antibody

WB: 0.25-0.5ug/ml (Mouse, Rat)
IHC-P (Embedded Section): 0.5-1ug/ml (Human, Mouse, Rat)
ICC: 2ug/ml (Human)
IF: 2ug/ml (Human)
FC/FACS: 1-3ug/1x106 cells (Human)
Direct ELISA: 0.1-0.5ug/ml (Human)
Tested Species: In-house tested species with positive results.

Product References and Citations for anti-IFT88 antibody

1. Cano, D. A., Murcia, N. S., Pazour, G. J., Hebrok, M. orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization. Development 131: 3457-3467, 2004.
2. Delaval, B., Bright, A., Lawson, N. D., Doxsey, S. The cilia protein IFT88 is required for spindle orientation in mitosis. Nature Cell Biol. 13: 461-468, 2011.
3. Huangfu, D., Liu, A., Rakeman, A. S., Murcia, N. S., Niswander, L., Anderson, K. V. Hedgehog signalling in the mouse requires intraflagellar transport proteins. Nature 426: 83-87, 2003.

Other Notes

Small volumes of anti-IFT88 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IFT88 purchase

MBS1753143 is an antibody targeting IFT88. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IFT88. It may not necessarily be applicable to this product.

NCBI GI #

972776298

NCBI GeneID

8100

NCBI Accession #

NP_001305420.1

UniProt Primary Accession #

Q13099

UniProt Related Accession #

Q13099

GenBank Nucleotide #

NP_001305420.1

NCBI Official Full Name

intraflagellar transport protein 88 homolog isoform 3

NCBI Official Synonym Full Names

intraflagellar transport 88

NCBI Official Symbol

IFT88

NCBI Official Synonym Symbols

DAF19; TG737; TTC10; hTg737; D13S1056E

UniProt Protein Name

Intraflagellar transport protein 88 homolog

UniProt Synonym Protein Names

Recessive polycystic kidney disease protein Tg737 homolog; Tetratricopeptide repeat protein 10; TPR repeat protein 10

Protein Family

Intraflagellar transport protein

UniProt Gene Name

IFT88

UniProt Synonym Gene Names

TG737; TTC10; TPR repeat protein 10

NCBI Protein Information

intraflagellar transport protein 88 homolog

NCBI Summary for IFT88

This gene encodes a member of the tetratrico peptide repeat (TPR) family. The encoded protein is involved in cilium biogenesis. Mutations of a similar gene in mouse can cause polycystic kidney disease. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2017]

UniProt Comments for IFT88

Involved in primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.

Research Articles on IFT88

1. The Intraflagellar Transport Protein IFT88 Is Disrupted in Cystic Fibrosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.