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FOXI1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1753154

Description: Rabbit IgG polyclonal antibody for FOXI1 detection. Tested with WB, IHC-P, ICC/IF, FCM, Direct ELISA in Human;Rat.Background: Forkhead box I1 is a protein that in humans is encoded by the FOXI1 gene. It is mapped to 5q35.1. This gene belongs to… More details

$210 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FOXI1, Polyclonal Antibody
Full Product Name
Anti-FOXI1 Antibody
Product Gene Name
anti-FOXI1 antibody
Product Synonym Names
Forkhead box protein I1; Forkhead-related protein FKHL10; Forkhead-related transcription factor 6; FREAC-6; Hepatocyte nuclear factor 3 forkhead homolog 3; HFH-3; HNF-3/fork-head homolog 3; FOXI1; FKHL10; FREAC6
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rat
Form/Format
Lyophilized
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Purity/Purification
Immunogen affinity purified.
Specificity
No cross reactivity with other proteins.
Preparation and Storage
Store at -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen store at -20 degree C for a longer time. Avoid repeated freezing and thawing.
OMIM
601093
3D Structure
ModBase 3D Structure for Q12951
Immunogen
E Coli-derived human FOXI1 recombinant protein (Position: M1-V378).
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-FOXI1 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS), Direct ELISA (EIA)
Application Notes for anti-FOXI1 antibody
WB: 0.25-0.5ug/ml (Human, Rat)
IHC-P (Embedded Section): 0.5-1ug/ml (Human)
ICC: 2ug/ml (Human)
IF: 2ug/ml (Human)
FC/FACS: 1-3ug/1x106 cells (Human)
Direct ELISA: 0.1-0.5ug/ml (Human)
Tested Species: In-house tested species with positive results.

Flow Cytometry (FC/FACS) of anti-FOXI1 antibody

Rabbit Anti-FOXI1 Polyclonal Antibody – Cat# MBS1753154

Immunofluorescence (IF) of anti-FOXI1 antibody

Rabbit Anti-FOXI1 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS1753154

Western Blot (WB) of anti-FOXI1 antibody

Figure 1. Western blot analysis of FOXI1 using anti-FOXI1 antibody.
Rabbit Anti-FOXI1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS1753154

Product References and Citations for anti-FOXI1 antibody

1. Blomqvist, S. R., Vidarsson, H., Fitzgerald, S., Johansson, B. R., Ollerstam, A., Brown, R., Persson, A. E. G., Bergstrom, G., Enerback, S. Distal renal tubular acidosis in mice that lack the forkhead transcription factor Foxi1. J. Clin. Invest. 113: 1560-1570, 2004.
2. Blomqvist, S. R., Vidarsson, H., Soder, O., Enerback, S. Epididymal expression of the forkhead transcription factor Foxi1 is required for male fertility. EMBO J. 25: 4131-4141, 2006.
3. Hulander, M., Kiernan, A. E., Blomqvist, S. R., Carlsson, P., Samuelsson, E. J., Johansson, B. R., Steel, K. P., Enerback, S. Lack of pendrin expression leads to deafness and expansion of the endolymphatic compartment in inner ears of Foxi1 null mutant mice. Development 130: 2013-2025, 2003.

Other Notes

Small volumes of anti-FOXI1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FOXI1 purchase

MBS1753154 is an antibody targeting FOXI1. Reactive in Human, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FOXI1. It may not necessarily be applicable to this product.

NCBI GI #
21618327
NCBI GeneID
2299
NCBI Accession #
NP_036320.2
UniProt Primary Accession #
Q12951
UniProt Related Accession #
Q12951
GenBank Nucleotide #
NP_036320.2
NCBI Official Full Name
forkhead box protein I1 isoform a
NCBI Official Synonym Full Names
forkhead box I1
NCBI Official Symbol
FOXI1
NCBI Official Synonym Symbols
HFH3; FKH10; HFH-3; FKHL10; FREAC6; FREAC-6
UniProt Protein Name
Forkhead box protein I1
UniProt Synonym Protein Names
Forkhead-related protein FKHL10; Forkhead-related transcription factor 6; FREAC-6; Hepatocyte nuclear factor 3 forkhead homolog 3; HFH-3; HNF-3/fork-head homolog 3
Protein Family
Forkhead box protein
UniProt Gene Name
FOXI1
UniProt Synonym Gene Names
FKHL10; FREAC6; FREAC-6; HFH-3; HNF-3/fork-head homolog 3
UniProt Entry Name
FOXI1_HUMAN
NCBI Protein Information
forkhead box protein I1

NCBI Summary for FOXI1

This gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene may play an important role in the development of the cochlea and vestibulum, as well as in embryogenesis. The encoded protein has been found to be required for the transcription of four subunits of a proton pump found in the inner ear, the kidney, and the epididymis. Mutations in this gene have been associated with deafness, autosomal recessive 4. [provided by RefSeq, Jan 2017]
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Research Articles on FOXI1

1. These data suggest that individuals with an SLC26A4 single-allele mutation, combined with FOXI1 or KCNJ10 gene mutations, do not suffer hearing loss during infancy

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FOXI1 antibody

 Reference Product  PubMed Publications
 SLC26A4 antibody  >19 publications with FOXI1 and SLC26A4
 KCNJ10 antibody  >13 publications with FOXI1 and KCNJ10
 GJB2 antibody  >2 publications with FOXI1 and GJB2
 EDA antibody  >1 publications with FOXI1 and EDA

Diseases associated with anti-FOXI1 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >15 publications with FOXI1 and Nervous System Diseases
 DEAFNESS, AUTOSOMAL RECESSIVE 4, WITH ENLARGED VESTIBULAR AQUEDUCT Antibodies  >10 publications with FOXI1 and DEAFNESS, AUTOSOMAL RECESSIVE 4, WITH ENLARGED VESTIBULAR AQUEDUCT
 Liver Neoplasms Antibodies  >2 publications with FOXI1 and Liver Neoplasms
 Craniofacial Abnormalities Antibodies  >2 publications with FOXI1 and Craniofacial Abnormalities
 Heart Diseases Antibodies  >1 publications with FOXI1 and Heart Diseases
 Liver Neoplasms, Experimental Antibodies  >1 publications with FOXI1 and Liver Neoplasms, Experimental
 Adenocarcinoma Antibodies  >1 publications with FOXI1 and Adenocarcinoma
 Fetal Death Antibodies  >1 publications with FOXI1 and Fetal Death
 Infertility, Female Antibodies  >1 publications with FOXI1 and Infertility, Female
 Infertility, Male Antibodies  >1 publications with FOXI1 and Infertility, Male

Organs/Tissues associated with anti-FOXI1 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >12 publications with FOXI1 and Kidney
 Lung Antibodies  >7 publications with FOXI1 and Lung
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